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Cited by 429

The DOI matches its Crossref record; 239 of the 239 references it cites were found in a registry or an index.

Colonization by Pneumocystis jirovecii and Its Role in Disease

Open access
Morris, Alison, Norris, Karen A.·2012·Clinical Microbiology Reviews

Abstract

SUMMARY: Although the incidence of Pneumocystis pneumonia (PCP) has decreased since the introduction of combination antiretroviral therapy, it remains an important cause of disease in both HIV-infected and non-HIV-infected immunosuppressed populations. The epidemiology of PCP has shifted over the course of the HIV epidemic both from changes in HIV and PCP treatment and prevention and from changes in critical care medicine. Although less common in non-HIV-infected immunosuppressed patients, PCP is now more frequently seen due to the increasing numbers of organ transplants and development of novel immunotherapies. New diagnostic and treatment modalities are under investigation. The immune response is critical in preventing this disease but also results in lung damage, and future work may offer potential areas for vaccine development or immunomodulatory therapy. Colonization with Pneumocystis is an area of increasing clinical and research interest and may be important in development of lung diseases such as chronic obstructive pulmonary disease. In this review, we discuss current clinical and research topics in the study of Pneumocystis and highlight areas for future research.

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Metadata

Authors
Morris, A., & Norris, K. A.
Venue
Clinical Microbiology Reviews
Published
2012-04
Volume
25
Issue
2
Pages
297-317
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2155954788
Cited by
429
References
239
FWCI
17.88
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Colonization by Pneumocystis jirovecii and Its Role in Disease. https://app.cochat.ai/papers/10.1128/cmr.00013-12
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Morris, A., & Norris, K. A. (2012). Colonization by Pneumocystis jirovecii and Its Role in Disease. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00013-12

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