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Cited by 855

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

KOVACS, JOSEPH A., HIEMENZ, JOHN W., MACHER, ABE M., STOVER, DIANE, MURRAY, HENRY W., SHELHAMER, JAMES, LANE, H. CLIFFORD, URMACHER, CARLOS, HONIG, CHRISTINE, LONGO, DAN L., PARKER, MARGARET M., NATANSON, CHARLES, PARRILLO, JOSEPH E., FAUCI, ANTHONY S., PIZZO, PHILIP A., MASUR, HENRY·1984·Annals of Internal Medicine

Abstract

Clinical features of 49 episodes of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome were compared with those of 39 episodes in patients with other immunosuppressive diseases. At presentation patients with the syndrome were found to have a longer median duration of symptoms (28 days versus 5 days, p = 0.0001), lower mean respiratory rate (23.4 versus 30, p = 0.005), and higher median room air arterial oxygen tension (69 mm Hg versus 52 mm Hg, p = 0.0002). The survival rate from 1979 to 1983 was similar for the two groups (57% and 50% respectively). Patients with the syndrome had a higher incidence of adverse reactions to trimethoprim-sulfamethoxazole (22 of 34 versus 2 of 17, p = 0.0007). Survivors with the syndrome at initial presentation had a significantly lower respiratory rate, and higher room air arterial oxygen tension, lymphocyte count, and serum albumin level compared to nonsurvivors. Pneumocystis carinii pneumonia presents as a more insidious disease process in patients with the syndrome, and drug therapy in these patients is complicated by frequent adverse reactions.

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Metadata

Authors
KOVACS, J. A., HIEMENZ, J. W., MACHER, A. M., STOVER, D., MURRAY, H. W., SHELHAMER, J., LANE, H. C., URMACHER, C., HONIG, C., LONGO, D. L., PARKER, M. M., NATANSON, C., PARRILLO, J. E., FAUCI, A. S., PIZZO, P. A., & MASUR, H.
Venue
Annals of Internal Medicine
Published
1984-05-01
Volume
100
Issue
5
Pages
663-671
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
OpenAlex
W2125803267
Cited by
855
References
10
FWCI
34.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies. https://app.cochat.ai/papers/10.7326/0003-4819-100-5-663
The paper
KOVACS, J. A., HIEMENZ, J. W., MACHER, A. M., STOVER, D., MURRAY, H. W., SHELHAMER, J., LANE, H. C., URMACHER, C., HONIG, C., LONGO, D. L., PARKER, M. M., NATANSON, C., PARRILLO, J. E., FAUCI, A. S., PIZZO, P. A., & MASUR, H. (1984). Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-100-5-663

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.