The DOI matches its Crossref record; 324 of the 324 references it cites were found in a registry or an index.
Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
Open accessAbstract
SUMMARY: In global terms, respiratory viral infection is a major cause of morbidity and mortality. Infancy, in particular, is a time of increased disease susceptibility and severity. Early-life viral infection causes acute illness and can be associated with the development of wheezing and asthma in later life. The most commonly detected viruses are respiratory syncytial virus (RSV), rhinovirus (RV), and influenza virus. In this review we explore the complete picture from epidemiology and virology to clinical impact and immunology. Three striking aspects emerge. The first is the degree of similarity: although the infecting viruses are all different, the clinical outcome, viral evasion strategies, immune response, and long-term sequelae share many common features. The second is the interplay between the infant immune system and viral infection: the immaturity of the infant immune system alters the outcome of viral infection, but at the same time, viral infection shapes the development of the infant immune system and its future responses. Finally, both the virus and the immune response contribute to damage to the lungs and subsequent disease, and therefore, any prevention or treatment needs to address both of these factors.
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Cites
2 retracted
Ventre, K., & Randolph, A. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000181.pub3 · Cited by 312
RetractedSurfactant therapy for bronchiolitis in critically ill infants
Ventre, K. M., Haroon, M., & Davison, C. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005150.pub2 · Cited by 58
RetractedDifferential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K. J., et al. (2006) · Nature · doi:10.1038/nature04734 · Cited by 3,888
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444
Coronavirus as a possible cause of severe acute respiratory syndrome
Peiris, J., Lai, S., Poon, L., Guan, Y., Yam, L., Lim, W., Nicholls, J., Yee, W., Yan, W., Cheung, M., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13077-2 · Cited by 2,915
(1958) · Journal of the American Pharmaceutical Association (Scientific ed.) · doi:10.1002/jps.3030470133 · Cited by 2,489
The Burden of Respiratory Syncytial Virus Infection in Young Children
Hall, C. B., Weinberg, G. A., Iwane, M. K., Blumkin, A. K., Edwards, K. M., Staat, M. A., Auinger, P., Griffin, M. R., Poehling, K. A., Erdman, D., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804877 · Cited by 2,246
Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
Smith, G. J. D., Vijaykrishna, D., Bahl, J., Lycett, S. J., Worobey, M., Pybus, O. G., Ma, S. K., Cheung, C. L., Raghwani, J., Bhatt, S., et al. (2009) · Nature · doi:10.1038/nature08182 · Cited by 2,243
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5’-phosphates
Pichlmair, A., Schulz, O., Tan, C. P., Näslund, T. I., Liljeström, P., Weber, F., & Reis e Sousa, C. (2006) · Science · doi:10.1126/science.1132998 · Cited by 2,210
A newly discovered human pneumovirus isolated from young children with respiratory tract disease
van den Hoogen, B. G., de Jong, J. C., Groen, J., Kuiken, T., de Groot, R., Fouchier, R. A. M., & Osterhaus, A. D. M. E. (2001) · Nature Medicine · doi:10.1038/89098 · Cited by 2,186
Cited by
Desforges, M., Le Coupanec, A., Dubeau, P., Bourgouin, A., Lajoie, L., Dubé, M., & Talbot, P. J. (2019) · Viruses · doi:10.3390/v12010014 · Cited by 1,048
The airway epithelium: soldier in the fight against respiratory viruses
Vareille, M., Kieninger, E., Edwards, M. R., & Regamey, N. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-10 · Cited by 655
Neurologic alterations due to respiratory virus infections
Bohmwald, K., Gálvez, N. M. S., Ríos, M., & Kalergis, A. M. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00386 · Cited by 636
“Neurological Manifestations Associated With Respiratory Viruses Infection Respiratory diseases caused by viral agents are one of the most critical problems in public health, as every year they are responsible for high rates of morbidity and mortality, mainly of young children, the elderly and immunocompromised individ…”
BackgroundHasan, M. R., Rawat, A., Tang, P., Jithesh, P. V., Thomas, E., Tan, R., & Tilley, P. (2016) · Journal of Clinical Microbiology · doi:10.1128/jcm.03050-15 · Cited by 243
Respiratory disease following viral lung infection alters the murine gut microbiota
Groves, H. T., Cuthbertson, L., James, P., Moffatt, M. F., Cox, M. J., & Tregoning, J. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00182 · Cited by 258
Self-citation
Metadata
- Authors
- Tregoning, J. S., & Schwarze, J.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2010-01
- Volume
- 23
- Issue
- 1
- Pages
- 74-98
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2163738297
- Cited by
- 747
- References
- 324
- FWCI
- 28.72
- Type
- journal article
- Language
- en
- Open access
- green
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