The DOI matches its Crossref record; 222 of the 222 references it cites were found in a registry or an index.
Avian Influenza Virus (H5N1): a Threat to Human Health
Open accessAbstract
SUMMARY: Pandemic influenza virus has its origins in avian influenza viruses. The highly pathogenic avian influenza virus subtype H5N1 is already panzootic in poultry, with attendant economic consequences. It continues to cross species barriers to infect humans and other mammals, often with fatal outcomes. Therefore, H5N1 virus has rightly received attention as a potential pandemic threat. However, it is noted that the pandemics of 1957 and 1968 did not arise from highly pathogenic influenza viruses, and the next pandemic may well arise from a low-pathogenicity virus. The rationale for particular concern about an H5N1 pandemic is not its inevitability but its potential severity. An H5N1 pandemic is an event of low probability but one of high human health impact and poses a predicament for public health. Here, we review the ecology and evolution of highly pathogenic avian influenza H5N1 viruses, assess the pandemic risk, and address aspects of human H5N1 disease in relation to its epidemiology, clinical presentation, pathogenesis, diagnosis, and management.
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Cites
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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia.
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Cited by
Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus
Gao, R., Cao, B., Hu, Y., Feng, Z., Wang, D., Hu, W., Chen, J., Jie, Z., Qiu, H., Xu, K., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1304459 · Cited by 2,310
Approved Antiviral Drugs over the Past 50 Years
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Update on Avian Influenza A (H5N1) Virus Infection in Humans
(2008) · New England Journal of Medicine · doi:10.1056/nejmra0707279 · Cited by 860
Complications of Viral Influenza
Rothberg, M. B., Haessler, S. D., & Brown, R. B. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2007.10.040 · Cited by 456
“26, 27 Cough, which may be productive, is common and hemoptysis has been described.”
BackgroundInfluentialThe Evolutionary Genetics and Emergence of Avian Influenza Viruses in Wild Birds
Dugan, V. G., Chen, R., Spiro, D. J., Sengamalay, N., Zaborsky, J., Ghedin, E., Nolting, J., Swayne, D. E., Runstadler, J. A., Happ, G. M., et al. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000076 · Cited by 396
Metadata
- Authors
- Peiris, J. S. M., de Jong, M. D., & Guan, Y.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2007-04
- Volume
- 20
- Issue
- 2
- Pages
- 243-267
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2145825913
- Cited by
- 1,007
- References
- 222
- FWCI
- 44.60
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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