The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Ventilator-Associated Pneumonia in Neonatal and Pediatric Intensive Care Unit Patients
Open accessAbstract
SUMMARY: Ventilator-associated pneumonia (VAP) is the second most common hospital-acquired infection among pediatric intensive care unit (ICU) patients. Empiric therapy for VAP accounts for approximately 50% of antibiotic use in pediatric ICUs. VAP is associated with an excess of 3 days of mechanical ventilation among pediatric cardiothoracic surgery patients. The attributable mortality and excess length of ICU stay for patients with VAP have not been defined in matched case control studies. VAP is associated with an estimated $30,000 in attributable cost. Surveillance for VAP is complex and usually performed using clinical definitions established by the CDC. Invasive testing via bronchoalveolar lavage increases the sensitivity and specificity of the diagnosis. The pathogenesis in children is poorly understood, but several prospective cohort studies suggest that aspiration and immunodeficiency are risk factors. Educational interventions and efforts to improve adherence to hand hygiene for children have been associated with decreased VAP rates. Studies of antibiotic cycling in pediatric patients have not consistently shown this measure to prevent colonization with multidrug-resistant gram-negative rods. More consistent and precise approaches to the diagnosis of pediatric VAP are needed to better define the attributable morbidity and mortality, pathophysiology, and appropriate interventions to prevent this disease.
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Cites
(2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200405-644st · Cited by 5,877
CDC definitions for nosocomial infections, 1988
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CDC definitions for nosocomial infections
Yangco, B. G. (1989) · American Journal of Infection Control · doi:10.1016/s0196-6553(89)80013-6 · Cited by 3,770
System, A. R. F. T. N. (2003) · American Journal of Infection Control · doi:10.1016/j.ajic.2003.09.002 · Cited by 2,915
System, A. R. F. T. N. (2004) · American Journal of Infection Control · doi:10.1016/j.ajic.2004.10.001 · Cited by 2,342
Inadequate Antimicrobial Treatment of Infections
Kollef, M. H., Sherman, G., Ward, S., & Fraser, V. J. (1999) · Chest · doi:10.1378/chest.115.2.462 · Cited by 1,805
Chastre, J., Wolff, M., Fagon, J.-Y., Chevret, S., Thomas, F., Wermert, D., Clementi, E., Gonzalez, J., Jusserand, D., Asfar, P., et al. (2003) · JAMA · doi:10.1001/jama.290.19.2588 · Cited by 1,376
Ely, E. W., Baker, A. M., Dunagan, D. P., Burke, H. L., Smith, A. C., Kelly, P. T., Johnson, M. M., Browder, R. W., Bowton, D. L., & Haponik, E. F. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352502 · Cited by 1,346
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Cited by
Jones, R. N. (2010) · Clinical Infectious Diseases · doi:10.1086/653053 · Cited by 716
Lee, P.-L., Lee, W.-T., & Chen, H.-L. (2017) · Pediatrics & Neonatology · doi:10.1016/j.pedneo.2015.10.014 · Cited by 43
Sahiledengle, B., Seyoum, F., Abebe, D., Geleta, E. N., Negash, G., Kalu, A., Woldeyohannes, D., Tekalegn, Y., Zenbaba, D., & Edward Quisido, B. J. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037997 · Cited by 37
Metadata
- Authors
- Foglia, E., Meier, M. D., & Elward, A.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2007-07
- Volume
- 20
- Issue
- 3
- Pages
- 409-425
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2169357305
- Cited by
- 316
- References
- 83
- FWCI
- 9.61
- Type
- journal article
- Language
- en
- Open access
- green
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- Foglia, E., Meier, M. D., & Elward, A. (2007). Ventilator-Associated Pneumonia in Neonatal and Pediatric Intensive Care Unit Patients. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00041-06
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
