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Cited by 826

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The Changing Epidemiology of Clostridium difficile Infections

Open access
Freeman, J., Bauer, M. P., Baines, S. D., Corver, J., Fawley, W. N., Goorhuis, B., Kuijper, E. J., Wilcox, M. H.·2010·Clinical Microbiology Reviews

Abstract

SUMMARY: The epidemiology of Clostridium difficile infection (CDI) has changed dramatically during this millennium. Infection rates have increased markedly in most countries with detailed surveillance data. There have been clear changes in the clinical presentation, response to treatment, and outcome of CDI. These changes have been driven to a major degree by the emergence and epidemic spread of a novel strain, known as PCR ribotype 027 (sometimes referred to as BI/NAP1/027). We review the evidence for the changing epidemiology, clinical virulence and outcome of treatment of CDI, and the similarities and differences between data from various countries and continents. Community-acquired CDI has also emerged, although the evidence for this as a distinct new entity is less clear. There are new data on the etiology of and potential risk factors for CDI; controversial issues include specific antimicrobial agents, gastric acid suppressants, potential animal and food sources of C. difficile , and the effect of the use of alcohol-based hand hygiene agents.

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Registry

Crossref · 10.1128/cmr.00082-09

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Metadata

Authors
Freeman, J., Bauer, M. P., Baines, S. D., Corver, J., Fawley, W. N., Goorhuis, B., Kuijper, E. J., & Wilcox, M. H.
Venue
Clinical Microbiology Reviews
Published
2010-07
Volume
23
Issue
3
Pages
529-549
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2123366827
Cited by
826
References
3
FWCI
39.58
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Changing Epidemiology of Clostridium difficile Infections. https://app.cochat.ai/papers/10.1128/cmr.00082-09
The paper
Freeman, J., Bauer, M. P., Baines, S. D., Corver, J., Fawley, W. N., Goorhuis, B., Kuijper, E. J., & Wilcox, M. H. (2010). The Changing Epidemiology of Clostridium difficile Infections. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00082-09

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.