Congenital Syphilis: a Review of Global Epidemiology

Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis

Gomez, G. B., Kamb, M. L., Newman, L. M., Mark, J., Broutet, N., & Hawkes, S. J. (2013) · Bulletin of the World Health Organization · doi:10.2471/blt.12.107623 · Cited by 634 · see citing works

Global burden of maternal and congenital syphilis and associated adverse birth outcomes—Estimates for 2016 and progress since 2012

Korenromp, E. L., Rowley, J., Alonso, M., Mello, M. B., Wijesooriya, N. S., Mahiané, S. G., Ishikawa, N., Le, L.-V., Newman-Owiredu, M., Nagelkerke, N., et al. (2019) · PLOS ONE · doi:10.1371/journal.pone.0211720 · Cited by 478 · see citing works

An Update on the Global Epidemiology of Syphilis

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Efficacy of Treatment for Syphilis in Pregnancy

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Efficacy of Treatment for Syphilis in Pregnancy

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Syphilis transmission: a review of the current evidence

Stoltey, J. E., & Cohen, S. E. (2015) · Sexual Health · doi:10.1071/sh14174 · Cited by 135 · see citing works

Prevalence of Syphilis among Pregnant Women in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

Hussen, S., & Tadesse, B. T. (2019) · BioMed Research International · doi:10.1155/2019/4562385 · Cited by 63 · see citing works

Outcomes of infants born to pregnant women with syphilis: a nationwide study in Korea

Lim, J., Yoon, S. J., Shin, J. E., Han, J. H., Lee, S. M., Eun, H. S., Park, M. S., & Park, K. I. (2021) · BMC Pediatrics · doi:10.1186/s12887-021-02502-9 · Cited by 43 · see citing works

Use of Interrupted Time Series Analysis in Understanding the Course of the Congenital Syphilis Epidemic in Brazil

Pinto, R. D. M., Valentim, R. A. D. M., da Silva, L. F., de Souza, G. F., Lima, T. S., de Oliveira, C. A. P., dos Santos, M. M., Miranda, A. E., da Cunha-Oliveira, A. C. G. D. P., Kumar, V., et al. (2021) · The Lancet Regional Health - Americas · doi:10.1016/j.lana.2021.100163 · Cited by 43 · see citing works

Evaluating coverage of maternal syphilis screening and treatment within antenatal care to guide service improvements for prevention of congenital syphilis in Countdown 2030 Countries

Trivedi, S., Taylor, M. M., Kamb, M. L., & Chou, D. (2020) · Journal of Global Health · doi:10.7189/jogh.10.010504 · Cited by 38 · see citing works

Prevalence, associated factors and clinical features of congenital syphilis among newborns in Mbarara hospital, Uganda

Oloya, S., Lyczkowski, D. A., Orikiriza, P., Irama, M., Boum, Y., Migisha, R., Kiwanuka, J. P., & Mwanga‐Amumpaire, J. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-03047-y · Cited by 27 · see citing works

Re-emergence of syphilis in women of reproductive age and its association with the increase in congenital syphilis in Mexico during 2010–2019: an ecological study

García-Cisneros, S., Herrera‐Ortíz, A., Olamendi-Portugal, M., & Sánchez-Alemán, M. Á. (2021) · BMC Infectious Diseases · doi:10.1186/s12879-021-06680-w · Cited by 22 · see citing works

Brazilian Protocol for Sexually Transmitted Infections 2020: epidemiological surveillance

Domingues, C. S. B., de Lannoy, L. H., Saraceni, V., Caruso, A., & Pereira, G. F. M. (2021) · Revista da Sociedade Brasileira de Medicina Tropical · doi:10.1590/0037-8682-549-2020 · Cited by 21 · see citing works

WHO method for estimating congenital syphilis to inform surveillance and service provision, Paraguay

Heath, K., Alonso, M., Aguilar, G., Samudio, T., Korenromp, E. L., Rowley, J. T., Suleiman, A., Shwe, Y. Y., Htin, K. C. W., Ishikawa, N., et al. (2022) · Bulletin of the World Health Organization · doi:10.2471/blt.20.271569 · Cited by 21 · see citing works

Screening and Treatment of Syphilis for Pregnant Women — China, 2011−2018

Qiao, Y., ¹ National Center for Women and Children's Health, C. C., Wang, X., Wang, Q., Li, Z., Jin, X., & Wang, A. (2020) · China CDC Weekly · doi:10.46234/ccdcw2020.123 · Cited by 20 · see citing works

Dermatovenereology of Russian Federation in 2020: Working Under a Pandemic

Kubanov, A. A., & Bogdanova, E. V. (2021) · Vestnik dermatologii i venerologii · doi:10.25208/vdv1261 · Cited by 20 · see citing works

High Incidence of Congenital Syphilis in New Zealand: A New Zealand Pediatric Surveillance Unit Study

Gilmour, L. S., Best, E. J., Duncanson, M. J., Wheeler, B. J., Sherwood, J., Thirkell, C. E., & Walls, T. (2022) · Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000003233 · Cited by 16 · see citing works

Adult female syphilis prevalence, congenital syphilis case incidence and adverse birth outcomes, Mongolia 2000–2016: Estimates using the Spectrum STI tool

Enkhbat, E., Korenromp, E. L., Badrakh, J., Zayasaikhan, S., Baya, P., Orgiokhuu, E., Jadambaa, N., Munkhbaatar, S., Khishigjargal, D., Khad, N., et al. (2018) · Infectious Disease Modelling · doi:10.1016/j.idm.2018.03.003 · Cited by 13 · see citing works

Congenital Syphilis in Honiara, Solomon Islands

Lifigao, M., Nasi, T., Titiulu, C., Lumasa, S., & Duke, T. (2020) · Journal of Tropical Pediatrics · doi:10.1093/tropej/fmaa017 · Cited by 7 · see citing works

Congenital Syphilis Case Surveillance in South Africa 2017–19: Experience, Challenges and Opportunities

Morifi, M., Malevu, N., Odayan, S., McCarthy, K., & Kufa, T. (2021) · Journal of Tropical Pediatrics · doi:10.1093/tropej/fmab079 · Cited by 7 · see citing works

Antimicrobial treatment and resistance in sexually transmitted bacterial infections

Jensen, J. S., & Unemo, M. (2024) · Nature Reviews Microbiology · doi:10.1038/s41579-024-01023-3 · Cited by 137 · see citing works

Congenital Syphilis—An Illustrative Review

Sankaran, D., Partridge, E., & Lakshminrusimha, S. (2023) · Children · doi:10.3390/children10081310 · Cited by 104 · see citing works

Maternal and congenital syphilis attributable to ethnoracial inequalities: a national record-linkage longitudinal study of 15 million births in Brazil

Paixão, E. S., Ferreira, A. J. F., Pescarini, J. M., Wong, K. L., Góes, E. F., Fiaccone, R. L., de Oliveira, G. L., Rebouças, P., Cardoso, A. M., Smeeth, L. L., et al. (2023) · The Lancet Global Health · doi:10.1016/s2214-109x(23)00405-9 · Cited by 49 · see citing works

Congenital Syphilis: A Re-Emerging but Preventable Infection

Salomè, S., Cambriglia, M. D., Montesano, G., Capasso, L., & Raimondi, F. (2024) · Pathogens · doi:10.3390/pathogens13060481 · Cited by 44 · see citing works

Syphilis vaccine development: Aligning vaccine design with manufacturing requirements

Waugh, S., & Cameron, C. E. (2024) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2024.2399915 · Cited by 14 · see citing works

Syphilis in pregnancy: A practical guide for prenatal care providers

Desjardins, A. A., Amaral, E., Miranda, J., Pasupathy, D., Martins, M. L., Buga, E., Aronoff, D., Money, D., Boucoiran, I., & FIGO Committee on Infections During Pregnancy and FIGO Committee on Health Systems Strengthening (2025) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70511 · Cited by 12 · see citing works

Repercussions of the COVID- 19 pandemic on maternal and congenital syphilis in South Brazil: a time series analysis 2010-2022

Echegaray, F., Hernandez, C. J., Sundar, K. G., Yang, L. Z., Cambou, M. C., Segura, E. R., de Melo, M. G., Santos, B. R., Varella, I. R. D. S., & Nielsen‐Saines, K. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-10901-x · Cited by 11 · see citing works

Computational methods applied to syphilis: where are we, and where are we going?

Albuquerque, G., Fernandes, F. R. D. S., Barbalho, I. M. P., Barros, D. M. S., de Morais, P. S. G., de Morais, A. H. F., dos Santos, M. M., Galvão-Lima, L. J., Sales-Moioli, A. I. L., dos Santos, J. P. Q., et al. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1201725 · Cited by 11 · see citing works

The prevalence of gestational syphilis in Malawi between 2014 and 2022: spatiotemporal modeling of population-level factors

Chirombo, J., Majamanda, A., Gunsaru, V., Yosefe, S., Ozituosauka, W., Mchoma, C., Morroni, C., Chipeta, E. K., MacPherson, P., & Freyne, B. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1242870 · Cited by 10 · see citing works

Opportunities to Optimize Outcomes of Diagnosis and Treatment of HIV and Syphilis in Pregnancy: the Quest to Eliminate Maternal and Vertical Transmission

Davey, D. J., de Voux, A., Shaetonhodi, N. G., Marks, M., Frigati, L. J., & Kufa, T. (2025) · Current HIV/AIDS Reports · doi:10.1007/s11904-025-00739-y · Cited by 8 · see citing works

Congenital Syphilis in the US: A Narrative Review

Azqul, M., Griner, S. B., & Pinto, C. N. (2024) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000002094 · Cited by 7 · see citing works

Congenital syphilis: time trend analysis and projection of cases

de Lima, D. M., da Silva, R. A. R., Pinheiro, Y. T., de Menezes, H. F., dos Santos, W. N., Holanda, J. R. R., Corréia, R. B. F., & de Mendonça, A. E. O. (2025) · Acta Paulista de Enfermagem · doi:10.37689/acta-ape/2025ao003054 · Cited by 7 · see citing works

Congenital syphilis: adverse pregnancy outcomes and neonatal disorders

Duan, B., Zhou, Y., Wang, X., Wang, H., Li, Y., Zhou, X., Tang, Y., Zhu, C., Liu, P., & Peng, J. (2025) · Infection · doi:10.1007/s15010-025-02591-z · Cited by 7 · see citing works

Neurosyphilis-Induced Psychosis in Europe: A Systematic Review of Case Reports

Jarocki, A., Klimczyk, K., Łysakowska, M., Bielec, F., & Pastuszak‐Lewandoska, D. (2024) · Pathogens · doi:10.3390/pathogens13110959 · Cited by 6 · see citing works

Syphilis Exposure During Pregnancy and Childhood Hospital Admissions in Brazil

Paixão, E. S., Carroll, O., Rodrigues, L. C., de Oliveira, G. L., Cardoso, A. M., Ribeiro‐Silva, R. D. C., Barreto, M. L., & Ichihara, M. Y. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.7471 · Cited by 6 · see citing works

Immunization with full-length TprC variants induces a broad response to surface-exposed epitopes of the Treponema pallidum repeat protein family and is partially protective in the rabbit model of syphilis

Giacani, L., Romeis, E., Haynes, A. M., Molini, B. J., Tantalo, L. C., Xu, L. H., Trejos, A. T., Keane, J., Mohamed, Z., Armstrong, T. D., et al. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.127406 · Cited by 6 · see citing works

Syphilis and pregnancy

Duarte, G. G., Melli, P. P. D. S., Miranda, A. E., Milanez, H. M. B. P. M., Menezes, M. L. B., Travassos, A. G., & Kreitchmann, R. (2024) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.61622/rbgo/2024fps09 · Cited by 6 · see citing works

Burden of syphilis among people living with HIV: a large cross-sectional study from Türkiye

Merdan, S., Merdan, Y. E., & Aydoğan, O. (2025) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-025-05199-1 · Cited by 5 · see citing works

Time-course transcriptomics reveals the impact of Treponema pallidum on microvascular endothelial cell function and phenotype

Waugh, S., Goodyear, M. C., Gomez, A., Ranasinghe, A., Lithgow, K., Falsafi, R., Hancock, R. E. W., Lee, A. H., & Cameron, C. E. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1649738 · Cited by 5 · see citing works

Prevention of congenital syphilis within antenatal PrEP services in South Africa: missed opportunities

Davey, D. J., de Voux, A., Hlatshwayo, L., Nelson, A., Frigati, L. J., Bheemraj, K., Wara, N. J., Mvududu, R., & Myer, L. (2024) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(24)00259-7 · Cited by 5 · see citing works

Estimation of the Incidence of Congenital Syphilis in Mexico Between 2019 and 2023

PÉREZ, E., Martin-Dorantes, M. A., & Méndez‐Domínguez, N. (2024) · Cureus · doi:10.7759/cureus.63913 · Cited by 4 · see citing works

The neglected role of partner treatment in congenital syphilis control in Brazil: nationwide evidence from 2007 to 2023

Fernandes, M. D. S., Menezes, R. C., Almeida, I. B. C., Fernandes, C. D., Ferreira, I. B. B., & Andrade, B. B. (2026) · The Lancet Regional Health - Americas · doi:10.1016/j.lana.2026.101434 · Cited by 4 · see citing works

Trends in Congenital Syphilis Incidence and Mortality in Brazil’s Southeast Region: A Time-Series Analysis (2008–2022)

Araújo, A. C. B., de Souza, O. F., Kersanach, B. B., Mozzer, J. S. C., Feitosa, V. L., Brandão, V. A., de Alencar, F. E. C., Oliveira, N. S., da Silva, A. V. B., & de Abreu, L. C. (2025) · Epidemiologia · doi:10.3390/epidemiologia6020022 · Cited by 3 · see citing works

Doxycycline post-exposure prophylaxis as prevention of STIs – the golden bullet?

Kohli, M., Elliott-Walker, T., Saunders, J., & Fifer, H. (2025) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2025.2510278 · Cited by 3 · see citing works

Syphilis screening in pregnancy: no time for complacency

Singh, A., Wong, T., & Robinson, J. L. (2025) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000001049 · Cited by 3 · see citing works

The contribution of PrEP programmes to triple elimination efforts: a cross-sectional study of status and opportunities

Martin, C. E., Ramatsoma, H., Koloane, N., Monametsi, M., Arries, S., Pleaner, M., & Mullick, S. (2025) · Frontiers in Reproductive Health · doi:10.3389/frph.2025.1637573 · Cited by 3 · see citing works

The utility of T. pallidum PCR testing in the diagnosis of congenital syphilis: a systematic review

Ryan, C., Houlihan, E., O’Reilly, D., McCallion, N., & Drew, R. J. (2025) · Scandinavian Journal of Infectious Diseases · doi:10.1080/23744235.2025.2588444 · Cited by 3 · see citing works

Autoconhecimento das gestantes sobre a sífilis congênita

Oliveira, L. R., da Câmara, M. M. G. C., do Valle, M. G., Alves, F. C., de Assis, F. C. M., Takatsu, E., Vezzani, M. F., Medeiros, J. S., de Araújo, B. C. N., Rodrigues, I. R., et al. (2024) · Brazilian Journal of Health Review · doi:10.34119/bjhrv7n2-087 · Cited by 3 · see citing works

Improved costs and turnaround time for Treponema pallidum detection utilising a real-time PCR assay developed for the Hologic Panther Fusion system

Nagappan, R., Smit, E., Nargesi, S. M., & McAuliffe, G. N. (2024) · Pathology · doi:10.1016/j.pathol.2024.09.011 · Cited by 2 · see citing works

Implementation Barriers in the Management of Maternal Syphilis by Midwives at Two Primary Healthcare Clinics in the Free State Province, South Africa

Tabane, N. E., Khaliq, O. P., Jassen, A., & Moodley, J. (2025) · Africa Journal of Nursing and Midwifery · doi:10.25159/2520-5293/18816 · Cited by 2 · see citing works

Prevalence and management of syphilis at primary healthcare level in the Free State, South Africa

Khaliq, O. P., Jassen, A., Tabane, N. E., & Moodley, J. (2025) · Southern African Journal of Infectious Diseases · doi:10.4102/sajid.v40i1.724 · Cited by 2 · see citing works

Potential use of saliva infrared spectra and machine learning for a minimally invasive screening test for congenital syphilis in infants

Dal'Ongaro, D. C., Cena, C., Marangoni, B. S., & Soares, D. D. A. (2025) · Scientific Reports · doi:10.1038/s41598-025-05144-4 · Cited by 2 · see citing works

The Outer Membrane Protein Tp92 of Treponema pallidum Induces BeWo Cells Apoptosis and Oxidative Stress via the Nrf2/keap1 Pathway

Huang, S., Zhao, Y., Xiong, S., Liu, Z., Ding, X., Yao, J., LIN, T. ‐., Yu, H., Zhang, X., & Zhao, F. (2025) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00346 · Cited by 2 · see citing works

Public and private antenatal care access and utilisation as determinants of triple antenatal test for HIV, syphilis, and HBV: Evidence from the Indonesian Health Survey

Wirawan, G. B. S., Kelly‐Hanku, A., Adawiyah, R. A., Wolter, A., Hegarty, B., Yuniar, Y., Ridwan, R., Januraga, P. P., Lestary, H., & Wulandari, L. P. L. (2025) · Women and Birth · doi:10.1016/j.wombi.2025.102153 · Cited by 2 · see citing works

Sífilis gestacional y atención prenatal: un estudio a la luz de las vulnerabilidades individuales, sociales y programáticas

Sarefino, A. D. O., Queiroz, A. B. A., Silva, K. G., Souza, N. V. D. D. O., Titara, N. M. L., Carvalho, A. R., Bezerra, J. D. F., Pinheiro, A. K. C., & da Rosa, A. F. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0270es · Cited by 2 · see citing works

Trends in Congenital Syphilis Cases by Maternal Country of Birth, Spain, 2016–2024

Hernando, V., Montaño, C., Fernandez, A., Molina, L., Perez, G., Viloria, L., Morales, R., Marcos, H., López-Corbeto, E., Silvestre, P., et al. (2026) · Emerging infectious diseases · doi:10.3201/eid3207.260146 · Cited by 2 · see citing works

A clinical case of early congenital syphilis

Khokhlova, A. P., Komarova, А. А., Sarkisyan, H. A., Zhuravleva, I. V., Mironova, V. A., Сергеевна, З. К., Zhirkova, Y. V., Makarova, L. M., Ovsyannikova, M. A., Belaya, A. L., et al. (2024) · CHILDREN INFECTIONS · doi:10.22627/2072-8107-2024-23-2-61-68 · Cited by 2 · see citing works

A Narrative Review of Syphilis Notification Systems in Korea: Change to Mandatory Surveillance System

Lee, S., & Choi, J. B. (2025) · Urogenital Tract Infection · doi:10.14777/uti.2550004002 · Cited by 2 · see citing works

Sífilis congénita, factores asociados, epidemiología y diagnóstico

Pincay, R. A. P., López, M. E. L., Marcillo, B. L. M., & Zamora, J. F. G. (2024) · Revista Científica de Salud BIOSANA · doi:10.62305/biosana.v4i4.243 · Cited by 2 · see citing works

Brief Report: Trends of Congenital Syphilis among Neonates in Canada 2012-2023

Nelson, C. R. M., Ferro, A., Naczk, K., Bitnun, A., Money, D., Narvey, M. R., Gravel, G., Merckx, J., den Hof, M. V., Scott, H., et al. (2025) · The Journal of Pediatrics Clinical Practice · doi:10.1016/j.jpedcp.2025.200146 · Cited by 2 · see citing works

First-year dynamics of the plasma virome and cytokine profile in infants born to mothers with syphilis

Dong, R., Lu, Y., Zheng, J., Zhuang, Y., Ma, Y., Cao, L., Li, Y., Kane, Y., Zhang, C., & Li, Y. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07827-6 · Cited by 1 · see citing works

Evaluating the prevalence and adequate treatment for congenital syphilis in a Brazilian reference maternity hospital

Duarte, A. O., Souza, M. S. D. J., da Silva, R. S. H., Vasconcelos, G. A., Martins, L. C., Alves, M. A. S., Machado, C. G., Cordeiro, S. M., dos Santos, C. C., Ferreira, J. R. D., et al. (2025) · Revista Paulista de Pediatria · doi:10.1590/1984-0462/2025/43/2024285 · Cited by 1 · see citing works

Subcutaneous Infusion of Benzathine Penicillin G Is Acceptable and Preferred Over Intramuscular Injections for Syphilis in Western Australian Sexual Health Clinic Attendees: A Mixed Methods Sub-study

Walley, S. L., Oliver, J. R., Enkel, S. L., Kupara, A., Swallow, S. K., Cotter, J., Hoyne, G. F., Hla, T. K., & Manning, L. A. (2025) · Patient · doi:10.1007/s40271-025-00764-4 · Cited by 1 · see citing works

Congenital Syphilis Presenting as Sepsis after the Neonatal Period: When Negative Maternal Serologies are Misleading

Vasconcelos, J., Neves, R. D. C., Berdianu, N., Silva, T. M., & Rocha, A. P. (2025) · Pediatric Infectious Disease · doi:10.5005/jp-journals-10081-1481 · Cited by 1 · see citing works

Loop-mediated isothermal amplification assays for the rapid discrimination of Treponema pallidum lineages and subspecies

Imai, K., Ohama, Y., Sato, A., Tanaka, M., Omachi, R., Takeuchi, K., Mizushina, H., Nakayama, S., Maeda, T., & Akeda, Y. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.01565-25 · Cited by 1 · see citing works

Towards the elimination of mother-to-child transmission of syphilis in the WHO European region: implications from a survey in the non-European Union and European economic area countries

Otani, M., Rowley, J. T., Kuchukhidze, G., Grankov, V., Bivol, S., WHO EURO non-EU/EEA STI Surveillance network, Vasili, A., Garcia, J. F., Hovhannisyan, H., Salimov, O., et al. (2025) · Discover Public Health · doi:10.1186/s12982-025-01157-6 · Cited by 1 · see citing works

Análise epidemiológica da sífilis em gestantes e da sífilis congênita em Porto Velho e Rondônia

Vieira, G. D. S. R., Amorim, G. D. A. S., Marques, E. A. C., de Paiva, I. S. F., das Mercês, S. V., Vieira, T. F. D. M., & Grillo, V. T. R. D. S. (2025) · Revista Brasileira de Medicina de Família e Comunidade · doi:10.5712/rbmfc20(47)4562 · Cited by 1 · see citing works

Long-term health effects of syphilis in cardiovascular diseases and neurological diseases: A systematic review and meta-analysis

Ying, Z., Li, X., Yin, N., & Gao, C. (2026) · Medicine · doi:10.1097/md.0000000000046480 · Cited by 1 · see citing works

“As long as you are married you cannot protect yourself against syphilis”: qualitative exploration of syphilis risk perception and antenatal care seeking among pregnant women in Uganda

Miller, A. P., Mugamba, S., Magada, B., Wynn, A., Saham, N., Ddaaki, W. G., Kyasanku, E., Bulamba, R., Olwa, V. O., Nkale, J. M., et al. (2026) · BMC Public Health · doi:10.1186/s12889-026-26263-1 · Cited by 1 · see citing works

Characteristics of Neonatal Congenital Syphilis at the University Teaching Hospital Children Division, Lusaka, Zambia: Retrospective Pilot Study

PhD, A. O. O., Kamusaki, M. K., Chembo, E. K., & Ogah, J.-A. O. (2026) · International journal of research and scientific innovation · doi:10.51244/ijrsi.2026.1304000052 · Cited by 1 · see citing works

Congenital Syphilis in an Infant at a Nigerian Hospital

Oyedeji, O. A., Oladibu, O. T., Oyelami, T. A., Adetoye, M. M., Osawu, G. O., Joel-Medewase, V. I., & Agelebe, E. (2026) · Annals of African Medicine · doi:10.4103/aam.aam_122_26 · Cited by 1 · see citing works

Congenital Syphilis Elimination in Latin America: A Systematic Analysis of Policy and Progress

Miranda, A. E., Dionne, J. A., Nuche‐Berenguer, B., Sereno, L. S., González, M. A., & Newman, L. (2026) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000002337 · Cited by 1 · see citing works

Lack of Serological Response by Delivery to Syphilis Treatment Does Not Impact Pregnancy Outcomes

Kaminiów, K., Kotlarz, A., Kiołbasa, M., & Pastuszczak, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144031 · Cited by 1 · see citing works

Sífilis congênita no Piauí: um retrato epidemiológico entre 2019 e 2023

Monteiro, N. P. D. S. D. R., Monteiro, N. P. D. S. D. R., Maia, L. L. S., & Mendes, C. M. D. M. (2024) · Revista Eletrônica Acervo Saúde · doi:10.25248/reas.e17990.2024 · Cited by 1 · see citing works

B-Cell Epitope Mapping of the Treponema pallidum Tp0435 Immunodominant Lipoprotein for Peptide-Based Syphilis Diagnostics

Keane, J. L., Bose, M., Molini, B. J., Konda, K. A., Vargas, S. K., Reyes-Diaz, M., Cáceres, C. F., Klausner, J. D., Treger, R. S., & Giacani, L. (2025) · Diagnostics · doi:10.3390/diagnostics15111443 · Cited by 1 · see citing works

Reemergence of Congenital Syphilis in the United States: A Narrative Review

Aboudawoud, O., Chaudhry, S., Dubey, P., & Hardy, G. (2024) · Venereology · doi:10.3390/venereology3020007

NEWBORN WITH CONGENITAL SYPHILIS: CASE REPORT

Raguž, S. G., & Raguž, M. J. (2024) · Zdravstveni glasnik · doi:10.47960/2303-8616.2024.1.9.226

Pré-natal em casos de suspeita de sífilis congênita em hospital pediátrico em Santa Catarina, Brasil

Strapazzon, I. F., & Carvalho, E. D. R. (2024) · Revista de Saúde Pública do Paraná · doi:10.32811/25954482-2024v7n4.1006

Syphilis During Pregnancy

Pintye, J. C. (2025) · MCN The American Journal of Maternal/Child Nursing · doi:10.1097/nmc.0000000000001079

Congenital syphilis on the rise. Review of a five-year period in a referral hospital in Portugal

Catarino, S., Carvalho, L., Ramos, A., Rodrigues, M. J. E., & Reis‐Melo, A. (2025) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2025.503800

Sífilis congénita en aumento. Revisión de 5 años en un hospital de referencia en Portugal

Catarino, S., Carvalho, L., Ramos, A., Rodrigues, M. J. E., & Reis‐Melo, A. (2025) · Anales de Pediatría · doi:10.1016/j.anpedi.2025.503800

Illuminating a dark field: a case of congenital syphilis in the context of rising rates in Australia and implications for screening guidelines

Montgomery, J. M., Robinson, A., & Koirala, A. (2025) · Public Health Research & Practice · doi:10.1071/pu24005

Medidas Preventivas e Manejo da Sífilis Congênita

Rocha, D. H. F., Silva, P. A. B., Aranha, T. B., Oliveira, L. A., Xavier, L. G., Pereira, D. Z., Barreto, R. F. S., de Freitas, E. G., Vale, M. E. R., Silva, R. N. R. D. O. S., et al. (2025) · Brazilian Journal of One Health · doi:10.70164/bjoh.v2i2.131

Neonates Born with Congenital Syphilis in CWM Hospital Suva, Fiji from 2018-2023

Pillay, K. N., Diau, J., Murthi, N., Singh, A. K., & Devi, A. (2025) · doi:10.38124/ijisrt/25apr456

Pesquisas e Ações em Saúde Pública - Edição XXII

de Freitas, G. B. L., & Resende, A. F. P. (2025) · Editora Pasteur eBooks · doi:10.59290/978-65-6029-232-1

Sífilis gestacional e congênita no estado do Maranhão, 2014-2024

de Carvalho, A. L. C., Vila-Nova, M. C., da Conceição, H. N., Araújo, A. M., Sousa, A. J. Z. D., & de Carvalho, R. A. S. (2025) · Contribuciones a las Ciencias Sociales · doi:10.55905/revconv.18n.6-176

A case report of congenital pemphigus syphiliticus in a preterm neonate: Insights into diagnosis, treatment, and long-term follow-up in a resource-limited country (Cambodia)

Sim, B., Din, V., Im, S., & Bin, S. (2025) · SAGE Open Medical Case Reports · doi:10.1177/2050313x251358975

Early congenital syphilis in the context of modern medicine

Ulitina, I. V., Pavlova, E. V., Kargapoltseva, E. A., & Biro, Y. V. (2025) · Vestnik dermatologii i venerologii · doi:10.25208/vdv16900

Fundamentals of infectious diseases and global health threats

Yadav, S., & Tripathi, M. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27461-9.00015-9

Syphilitic Hepatitis in Infancy Presenting with Cholestatic Jaundice and Inguinal Hernia: A Case Report

Putra, A. I. Y. D., Mustika, P. P., & Agung, M. S. A. (2025) · Jurnal Gastrohepatologi Anak Indonesia/Archives of Pediatric Gastroenterology, Hepatology, and Nutrition · doi:10.58427/apghn.4.3.2025.141-150

Epidemiology of Rare Diseases

Eslick, G. D. (2025) · Springer eBooks · doi:10.1007/978-1-4614-6625-3_91-1

Rising Global Trend of Syphilis and Our Institutional Experience for the Last 12 Years: A Gentle Recite of Syphilis History from Emergence to Speculated Postcoronavirus Disease 2019 Resurgence

Sharma, R. K., Singh, R., Chokkra, V., Mehta, K. S., Chauhan, P. S., & Lath, A. (2025) · Clinical Dermatology Review · doi:10.4103/cdr.cdr_75_25

Sifilide congenita: è ancora un problema?

Abbagnato, L., Niccolini, N., & Selicorni, A. (2025) · Medico e Bambino · doi:10.53126/meb44593

A forgotten foe: Congenital syphilis in the modern era

Vani, T., Rithika, G. V., Teja, G. S., & Kumar, T. S. P. (2025) · Indian Journal of Sexually Transmitted Diseases and AIDS · doi:10.4103/ijstd.ijstd_114_25

Congenital Syphilis: A Threat to Neonatal Health

Holland, M., Steger, A., & Jnah, A. J. (2025) · Neonatal Network The Journal of Neonatal Nursing · doi:10.1891/nn-2025-0020

Management of Infants Born to Pregnant Women with Reactive Syphilis Serology: Resource Saving from Using the Current Centers for Disease Control Guidelines

Lofiego, P. L. F., Tse‐Chang, A., Gratrix, J., Smyczek, P., Robinson, J. L., & Kumar, M. (2025) · American Journal of Perinatology · doi:10.1055/a-2768-2636

Uso de técnicas moleculares de última generación para la detección de Treponema pallidum en sífilis gestacional y congénita: una contribución para la salud materno-infantil

Olarte, N. M., Castro, A. M. B., Rozo, Z. L. C., Márquez, I. A. V., Abril, D., Fuentes, L., Cruz, R. L. L., Ramírez, S. H. O., Madera, J. A. M., Cabrera, P. J. R., et al. (2025) · Boletín Epidemiológico Distrital - Bed · doi:10.56085/bed.620

Characteristics and effectiveness of maternal health interventions to prevent mother-to-child transmission (PMTCT) of syphilis in a global setting: a scoping review using Intervention Mapping as a framework

Tang, J., Sajja, A., Markham, C. M., Hébert, E. T., Stafford, I., Dacso, S. T., & Peskin, M. F. (2026) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-025-08598-6

SÍFILIS CONGÊNITA EM UMA CAPITAL DA AMAZÔNIA OCIDENTAL: UM PROBLEMA PERSISTENTE DE SAÚDE PÚBLICA

dos Santos, I. P., de Oliveira, J. M. F., Gonçalves, M. D. S. A., da Rocha, S. R. P., Ampuero, P. M., Menezes, C. C. R., Garcia, C. G. D. M., & Ferreira, A. P. (2026) · Revista Contemporânea · doi:10.56083/rcv6n1-054

The Congenital Syphilis Surge

Pithia, N., Nielsen‐Saines, K., & Adachi, K. (2026) · Advances in Pediatrics · doi:10.1016/j.yapd.2025.12.005

Characteristics and geographical distribution of syphilis among people with human immunodeficiency virus and the National Population in Republic of Korea

Baek, Y. J., Kim, S., Lee, E., Park, B., Jeong, O., Jung, J., Choi, J. Y., & Kim, T. Y. (2026) · PLoS ONE · doi:10.1371/journal.pone.0340324

Parrot's pseudoparalysis: a case of congenital syphilis

Yalçın, B. A. (2026) · Journal of Multidisciplinary Orthopaedic Surgery · doi:10.64575/mz31g355

Emergency Department Screening of Syphilis During Pregnancy

Walden, K., Andrew, B., Brosnan, A., & Holmes, V. (2026) · SteadFAST Case Reports in PA Studies · doi:10.64918/20.500.12503/33509

A Clinical Review of Congenital and Perinatal Infections: From Womb to Follow-Up

Çeri, A., & Gültekin, N. D. (2026) · Pediatrics in Review · doi:10.1542/pir.2025-006983

Prevalence of syphilis and associated factors among pregnant people attending antenatal care at public hospitals in Eastern Tigray, Ethiopia, an institutional based cross-sectional study

Desta, A. G., Tsge, T. W., Mamay, G., Hailu, T., Gebremedhin, H., Hailesilase, G. G., Abraha, B. H., & Mengesha, M. B. (2026) · International Journal of STD & AIDS · doi:10.1177/09564624261449001

Global, regional, and national burdens of HIV and syphilis in children aged 0–14 years from 1990 to 2021: a systematic analysis from the global burden of disease study 2021

Tan, R., Ren, S., Feng, W., Tang, H., Ren, X., & Wang, H. (2026) · Critical Public Health · doi:10.1080/09581596.2026.2678631

Gestational syphilis and prenatal care: a study in light of individual, social, and programmatic vulnerabilities

Sarefino, A. D. O., Queiroz, A. B. A., Silva, K. G., Souza, N. V. D. D. O., Titara, N. M. L., Carvalho, A. R., Bezerra, J. D. F., Pinheiro, A. K. C., & da Rosa, A. F. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0270en

Sífilis gestacional e acompanhamento pré-natal: um estudo frente às vulnerabilidades individuais, sociais e programáticas

Sarefino, A. D. O., Queiroz, A. B. A., Silva, K. G., Souza, N. V. D. D. O., Titara, N. M. L., Carvalho, A. R., Bezerra, J. D. F., Pinheiro, A. K. C., & da Rosa, A. F. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0270pt

SYPHILIS RESURGENCE IN THE 21ST CENTURY: GLOBAL EPIDEMIOLOGICAL SHIFTS, CONGENITAL BURDEN, AND IMPLICATIONS FOR PREVENTION

Kacperczyk, J., Bezak, J., Winkler, M., Arczewska, A., Stolarczyk, M., Jagura-Sukiennik, A., Michałowska, K., Kolanowski, O., Zaborowski, M., & Purgal-Zaborowska, K. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.1(49).2026.4869

High-throughput profiling of the IgG and IgA response to the Treponema pallidum subsp. pallidum proteome in syphilis patients

Giacani, L., Xu, L. H., Oberai, A., Pablo, J. V., Hung, C., Teng, A., Shandling, A. D., Konda, K. A., Vargas, S. K., Reyes-Diaz, M., et al. (2026) · mBio · doi:10.1128/mbio.00820-26

Universal syphilis screening for pregnant patients admitted to labor and delivery—a quality improvement initiative

West, S., Duffy, J., Kassem, Z., & Peterson, A. (2026) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2026.102026

Sífilis congénita: serie de casos en hospital de tercer nivel

Mera, J. R. R., Reyes, N. F. L., & Asinc, J. C. (2026) · Revista Latinoamericana de Infectología Pediátrica · doi:10.35366/123457

Experiência de mulheres jovens com sífilis gestacional sob a ótica conceitual da esperança

Wernet, M., Charepe, Z. B., Festas, C., Silveira, A. O., & Nakao, P. A. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0118pt

The experience of young women with gestational syphilis from the conceptual perspective of hope

Wernet, M., Charepe, Z. B., Festas, C., Silveira, A. O., & Nakao, P. A. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0118en

La experiencia de mujeres jóvenes con sífilis gestacional desde la perspectiva conceptual de la esperanza

Wernet, M., Charepe, Z. B., Festas, C., Silveira, A. O., & Nakao, P. A. (2026) · Revista da Escola de Enfermagem da USP · doi:10.1590/1980-220x-reeusp-2025-0118es

Case Report: Congenital syphilis presenting with respiratory symptoms in an infant

Feng, Y., & Lei, Y. (2026) · Frontiers in Pediatrics · doi:10.3389/fped.2026.1936401

The return of congenital syphilis: Disease spectrum and modifiable factors in a semi-rural regional hospital in KwaZulu-Natal Province, South Africa

Tiemersma, S., Setlatjile, P. A., Lobenstein, J. V., & Moran, N. (2026) · South African Medical Journal · doi:10.7196/samj.2026.v116i7.3064

Congenital syphilis and oral involvement: Treponema pallidum detection and oral development in exposed children

Veiga, L. C. G., Castro, R. C. C., Silva, N. C., TIAGO, L. B., Correa, M. R., da Silva, C. B., Sousa, C. R. D. C. E., Geraldo-Martins, V. R., Oliveira, M. A. H. D. M., & Nogueira, R. D. (2026) · Einstein (São Paulo) · doi:10.31744/einstein_journal/2026ao2472

Sífilis na gestação: desafios diagnósticos, terapêuticos e assistenciais no período perinatal e parto.

Ribeiro, I. C., Tasso, I. N., & Rodrigues, A. L. D. C. (2026) · Revista fisio&terapia. · doi:10.69849/d13erb80

Sífilis Gestacional e Congênita e Sua Relação com o Objetivo de Desenvolvimento Sustentável (ODS) 3: Desafios Para a Eliminação da Transmissão Vertical na Agenda 2030

Habermann, M. A. M., Habermann, G., Perrotti, G. E., & Somensi, L. B. (2026) · Journal of Lifestyle and SDGs Review · doi:10.47172/2965-730x.sdgsreview.v6.n07.pe08351

Congenital Syphilis: A Re-Emerging but Preventable Infection

Salomè, S., Cambriglia, M. D., Montesano, G., Capasso, L., & Raimondi, F. (2024) · Pathogens · doi:10.3390/pathogens13060481 · Cited by 44 · see citing works

Reaching beyond pregnant women to eliminate mother-to-child transmission of syphilis in Africa

Trope, L. A., Wijesooriya, N. S., Broutet, N. J. N., Temmerman, M., & Newman, L. M. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2014.919221 · Cited by 12 · see citing works

Resurgence of congenital syphilis: new strategies against an old foe

Moseley, P., Bamford, A., Eisen, S., Lyall, H., Kingston, M., Thorne, C., Piñera, C., Rabie, H., Prendergast, A. J., & Kadambari, S. (2024) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(23)00314-6 · Cited by 84 · see citing works

Elimination of Mother-To-Child Transmission of Syphilis in the Americas—A Goal That Must Not Slip Away

Stamm, L. V., & Noda, A. A. (2016) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000538 · Cited by 5 · see citing works

Assessing progress towards the elimination of mother-to-child transmission of syphilis in Peru: A national retrospective analysis

Qquellon, J., Cardenas‐Jara, A., Castro-Caparó, A., & Carrasco‐Escobar, G. (2026) · PLOS Global Public Health · doi:10.1371/journal.pgph.0006951 · Cited by 1 · see citing works