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Cited by 630

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease

Open access
Hendrickson, Barbara A., Gokhale, Ranjana, Cho, Judy H.·2002·Clinical Microbiology Reviews

Abstract

SUMMARY: The chronic inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are recognized as important causes of gastrointestinal disease in children and adults. In this review we delineate the clinical manifestations and diagnostic features of IBD. In addition, we summarize important recent advances in our understanding of the immune mediators of intestinal inflammation. This information has led to new therapeutic approaches in IBD. Further, we discuss the considerable data that point to the significance of genetic factors in the development of IBD and the genetic loci which have been implicated through genomewide searches. The commensal bacterial flora also appears to be a critical element, particularly in regards to Crohn's disease, although the precise role of the bacteria in the disease manifestations remains unclear. Current investigations promise to yield fresh insights in these areas.

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Crossref · 10.1128/cmr.15.1.79-94.2002

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Metadata

Authors
Hendrickson, B. A., Gokhale, R., & Cho, J. H.
Venue
Clinical Microbiology Reviews
Published
2002-01
Volume
15
Issue
1
Pages
79-94
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2116085563
Cited by
630
References
2
FWCI
7.50
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.