The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Microorganisms Resistant to Free-Living Amoebae
Open accessAbstract
SUMMARY: Free-living amoebae feed on bacteria, fungi, and algae. However, some microorganisms have evolved to become resistant to these protists. These amoeba-resistant microorganisms include established pathogens, such as Cryptococcus neoformans, Legionella spp.,Chlamydophila pneumoniae,Mycobacterium avium,Listeria monocytogenes,Pseudomonas aeruginosa, and Francisella tularensis, and emerging pathogens, such as Bosea spp.,Simkania negevensis, Parachlamydia acanthamoebae, and Legionella-like amoebal pathogens. Some of these amoeba-resistant bacteria (ARB) are lytic for their amoebal host, while others are considered endosymbionts, since a stable host-parasite ratio is maintained. Free-living amoebae represent an important reservoir of ARB and may, while encysted, protect the internalized bacteria from chlorine and other biocides. Free-living amoebae may act as a Trojan horse, bringing hidden ARB within the human “Troy,” and may produce vesicles filled with ARB, increasing their transmission potential. Free-living amoebae may also play a role in the selection of virulence traits and in adaptation to survival in macrophages. Thus, intra-amoebal growth was found to enhance virulence, and similar mechanisms seem to be implicated in the survival of ARB in response to both amoebae and macrophages. Moreover, free-living amoebae represent a useful tool for the culture of some intracellular bacteria and new bacterial species that might be potential emerging pathogens.
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Cites
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
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Lateral gene transfer and the nature of bacterial innovation
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“Models for testing virulence were developed by using Dictyostelium discoideum as a host (53, 105, 197, 221, 222).”
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Cited by
Khan, S. J., Deere, D., Leusch, F. D. L., Humpage, A., Jenkins, M., & Cunliffe, D. (2015) · Water Research · doi:10.1016/j.watres.2015.08.018 · Cited by 251
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Laencina, L., Dubois, V., Le Moigne, V., Viljoen, A., Majlessi, L., Pritchard, J., Bernut, A., Piel, L., Roux, A.-L., Gaillard, J.-L., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1713195115 · Cited by 147
Dictyostelium as host model for pathogenesis
Steinert, M., & Heuner, K. (2005) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00493.x · Cited by 144
Specific host genes required for the killing of Klebsiella bacteria by phagocytes
Benghezal, M., Fauvarque, M.-O., Tournebize, R., Froquet, R., Marchetti, A., Bergeret, E., Lardy, B., Klein, G., Sansonetti, P., Charette, S. J., et al. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00607.x · Cited by 136
Metadata
- Authors
- Greub, G., & Raoult, D.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2004-04
- Volume
- 17
- Issue
- 2
- Pages
- 413-433
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2131227464
- Cited by
- 1,066
- References
- 7
- FWCI
- 19.56
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
