The ABCs of Candida albicans Multidrug Transporter Cdr1

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Biofilm of Candida albicans : formation, regulation and resistance

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Biofilm formation in medically important Candida species

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Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungus Candida albicans

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ABC Transporter Genes Show Upregulated Expression in Drug-Resistant Clinical Isolates of Candida auris: A Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

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Multiple roles of ABC transporters in yeast

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Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

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Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling

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Multidrug transporters of Candida species in clinical azole resistance

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Yeast ABC transporters in lipid trafficking

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Evaluation of Jatrophane Esters from Euphorbia spp. as Modulators of Candida albicans Multidrug Transporters

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Host-Pathogen Interactions Mediated by MDR Transporters in Fungi: As Pleiotropic as it Gets!

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Emerging Mechanisms of Drug Resistance in Candida albicans

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All about CDR transporters: Past, present, and future

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Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance

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Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms

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Phosphatidylserine decarboxylase governs plasma membrane fluidity and impacts drug susceptibilities of Candida albicans cells

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Resistance to antifungal therapies

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PDR-like ABC systems in pathogenic fungi

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Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters

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Vacuolar Sequestration of Azoles, a Novel Strategy of Azole Antifungal Resistance Conserved across Pathogenic and Nonpathogenic Yeast

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ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis

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Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

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Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans

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In vitro NTPase activity of highly purified Pdr5, a major yeast ABC multidrug transporter

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Distinct roles of the 7-transmembrane receptor protein Rta3 in regulating the asymmetric distribution of phosphatidylcholine across the plasma membrane and biofilm formation inCandida albicans

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ABC protein CgABCF2 is required for asexual and sexual development, appressorial formation and plant infection in Colletotrichum gloeosporioides

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Differentially Regulated Transcription Factors and ABC Transporters in a Mitochondrial Dynamics Mutant Can Alter Azole Susceptibility of Aspergillus fumigatus

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Magnesium deprivation affects cellular circuitry involved in drug resistance and virulence in Candida albicans

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Small molecules restore azole activity against drug-tolerant and drug-resistant Candida isolates

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Structure, function, and inhibition of catalytically asymmetric ABC transporters: Lessons from the PDR subfamily

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Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps

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Positive regulation of the Candida albicans multidrug efflux pump Cdr1p function by phosphorylation of its N-terminal extension

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LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles

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W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans

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Clonal spread and azole-resistant mechanisms of non-susceptible Candida albicans isolates from vulvovaginal candidiasis patients in three Shanghai maternity hospitals

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Retrograde signaling disruption influences ABC superfamily transporter, ergosterol and chitin levels along with biofilm formation in Candida albicans

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Genomics insights of candidiasis: mechanisms of pathogenicity and drug resistance

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Genome‐wide transcriptional response of the causal soybean sudden death syndrome pathogen Fusarium virguliforme to a succinate dehydrogenase inhibitor fluopyram

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Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes

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Otilonium Bromide Exhibits Potent Antifungal Effects by Blocking Ergosterol Plasma Membrane Localization and Triggering Cytotoxic Autophagy in Candida Albicans

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How fungal multidrug transporters mediate hyper resistance through DNA amplification and mutation

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Split tasks of asymmetric nucleotide‐binding sites in the heterodimeric ABC exporter EfrCD

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Expression pattern of drug-resistance genes ERG11 and TAC1 in Candida albicans Clinical isolates

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Comparative evaluation of biologically and chemically synthesized zinc oxide nanoparticles for preventing Candida auris biofilm

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Control of metabolite efflux in microbial cell factories: current advances and future prospectsPreprint

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Phospholipid biosynthesis disruption renders the yeast cells sensitive to antifungals

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Small molecule II-6s synergises with fluconazole against Candida albicans

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Broad susceptibility of Candida auris strains to 8-hydroxyquinolines and mechanisms of resistance

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The putative ABC transporter encoded by the orf19.4531 plays a role in the sensitivity ofCandida albicanscells to azole antifungal drugs

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An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites

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Epithelial Cell Transforming 2 and Aurora Kinase B Modulate Formation of Stress Granule–Containing Transcripts from Diverse Cellular Pathways in Astrocytoma Cells

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Modulators of Candida albicans Membrane Drug Transporters: A Lucrative Portfolio for the Development of Effective Antifungals

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Flow Cytometric Measurement of Efflux in Candida Species

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Antifungal activity of Thymus kotschyanus extract: An in vitro study on the expression of CDR1 and CDR2 genes in clinical isolates of Candida albicans

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FungAMR: A comprehensive portrait of antimicrobial resistance mutations in fungiPreprint

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RNA-Seq Provides Insights into the Mechanisms Underlying Ilyonectria robusta Responding to Secondary Metabolites of Bacillus methylotrophicus NJ13

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Deciphering the multidrug resistance paradigm in Candida auris

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An actin depolymerizing agent 19,20-epoxycytochalasin Q of Xylaria sp. BCC 1067 enhanced antifungal action of azole drugs through ROS-mediated cell death in yeast

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Molecular dissection studies of TAC1, a transcription activator of Candida drug resistance genes of the human pathogenic fungus Candida albicans

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Make Azoles Active Again: Chalcones as Potent Reversal Agents of Transporters-Mediated Resistance in Candida Albicans

Nim, S., Baghel, P., Tran‐Nguyen, V., Pérès, B., Nguyen, K.-A., Pietro, A. D., Falson, P., Prasad, R., & Boumendjel, A. (2018) · Future Medicinal Chemistry · doi:10.4155/fmc-2018-0081 · Cited by 7

Study on the impact of biofilm formation by Candida albicans in recurrent vulvovaginal candidiasis on drug susceptibility

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Generation of antifungals to combat drug resistance using language models and diffusion models

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Unravelling Drug Resistance in Candida Species: Genetic, Biofilm, Transcriptional, and Epigenetic Perspectives

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Potential risk of cross-resistance to voriconazole in HIV/AIDS patients with Talaromyces marneffei infection and the mechanisms of the cross-resistance

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HyperdCas12a-based multiplexed genetic regulation in Candida albicans

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Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

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Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii

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Transcriptome Analysis of mfs2-Defective Penicillium digitatum Mutant to Reveal Importance of Pdmfs2 in Developing Fungal Prochloraz Resistance

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Genomic landscape of the DHA1 family in Candida auris and mapping substrate repertoire of CauMdr1

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Mechanisms of antifungal resistance

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