Cited by 261Iron Metabolism and DisordersBacterial Genetics and BiotechnologyEscherichia coli research studies

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Sequestration and Scavenging of Iron in Infection

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Parrow, Nermi L., Fleming, Robert E., Minnick, Michael F.·2013·Infection and Immunity

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Abstract

The proliferative capability of many invasive pathogens is limited by the bioavailability of iron. Pathogens have thus developed strategies to obtain iron from their host organisms. In turn, host defense strategies have evolved to sequester iron from invasive pathogens. This review explores the mechanisms employed by bacterial pathogens to gain access to host iron sources, the role of iron in bacterial virulence, and iron-related genes required for the establishment or maintenance of infection. Host defenses to limit iron availability for bacterial growth during the acute-phase response and the consequences of iron overload conditions on susceptibility to bacterial infection are also examined. The evidence summarized herein demonstrates the importance of iron bioavailability in influencing the risk of infection and the ability of the host to clear the pathogen.

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Acute-Phase Proteins and Other Systemic Responses to Inflammation
Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., & Kaplan, J. (2004) · Science · doi:10.1126/science.1104742 · Cited by 4,803
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166
Bacterial iron homeostasis
Andrews, S. C., Robinson, A. K., & Rodríguez-Quiñones, F. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00055-x · Cited by 2,702
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B. K., & Ganz, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420945 · Cited by 2,650 · cited 11×
“The APR markedly alters host iron metabolism in ways that serve to minimize iron bioavailability to pathogens (Fig.”
BackgroundInfluential
The catalytic decomposition of hydrogen peroxide by iron salts
Haber, F., & Weiss, J. (1934) · Proceedings of the Royal Society of London. Series A - Mathematical and Physical Sciences · doi:10.1098/rspa.1934.0221 · Cited by 2,571
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
Park, C. H., Valore, E. V., Waring, A. J., & Ganz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008922200 · Cited by 2,168
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
Nemeth, E., Valore, E. V., Territo, M., Schiller, G., Lichtenstein, A., & Ganz, T. (2003) · Blood · doi:10.1182/blood-2002-10-3235 · Cited by 1,417
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
Krause, A., Neitz, S., Mägert, H.-J., Schulz, A., Forssmann, W.-G., Schulz-Knappe, P., & Adermann, K. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01920-7 · Cited by 1,324
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
Nicolas, G., Chauvet, C., Viatte, L., Danan, J. L., Bigard, X., Devaux, I., Beaumont, C., Kahn, A., & Vaulont, S. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215686 · Cited by 1,214

Show all 179 references

Research works printed but not linked: 1

ChaberekSMartellAE. 1959. Organic sequestering agents. John Wiley & Sons, Inc, New York, NY.

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Authors: Parrow, N. L., Fleming, R. E., & Minnick, M. F.
Affiliations: National Institutes of Health (US)
Saint Louis University (US)
University of Montana (US)
ORCID: Parrow, Nermi L.
Fleming, Robert E.
Minnick, Michael F.
Venue: Infection and Immunity
Publisher: American Society for Microbiology
Published: 2013-10
Volume: 81
Issue: 10
Pages: 3503-3514
ISSN: 0019-9567 (ISSN-L)
1098-5522
DOI: 10.1128/iai.00602-13
PMC: PMC3811770
OpenAlex: W2126286427
Cited by: 261
References: 179
Citations by year: 2026: 14 · 2025: 26 · 2024: 25 · 2023: 24 · 2022: 25 · 2021: 26 · 2020: 31 · 2019: 26 · 2018: 16 · 2017: 16 · 2016: 11 · 2015: 11 · 2014: 8 · 2013: 1
FWCI: 7.42
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Infection and Immunity (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
The Mathematics Enthusiast (submittedVersion)
Funders: National Institutes of Health
Topics: Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
Keywords: iron sequestration, iron scavenging, iron bioavailability, bacterial virulence, host-pathogen interaction, acute phase response, iron overload, bacterial iron acquisition, host defense against infection
MeSH terms: Animals, Bacteria, Homeostasis, Humans, Iron

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Sequestration and Scavenging of Iron in Infection

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