The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Lack of Gender-Specific Antibody Recognition of Products from Domains of a var Gene Implicated in Pregnancy-Associated Plasmodium falciparum Malaria
Open accessAbstract
Gender-specific and parity-dependent acquired antibody recognition is characteristic of variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent Plasmodium falciparum involved in pregnancy-associated malaria (PAM). However, antibody recognition of recombinant products of a specific VSA gene ( 2O2var1 ) implicated in PAM and transcribed by a CSA-adhering parasite line did not have these characteristics. Furthermore, we could not demonstrate preferential transcription of 2O2var1 in the CSA-adhering line versus the unselected, parental isolate. Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM.
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Sex-specific and parity-dependent plasma IgG recognition of IEs after Saimiri brain endothelial cell selection has not been reported.
“Furthermore, sex-specific and parity-dependent plasma IgG recognition of IEs after Saimiri brain endothelial cell selection has not been reported, but domains from VAR1CSA do not show the expected VSAPAM-type sex-specific and parity-dependent IgG recognition (30).”
From Evidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria (2004) · cites this paper as [30]
Domains from VAR1CSA do not show the expected VSAPAM-type sex-specific and parity-dependent IgG recognition.
“Furthermore, sex-specific and parity-dependent plasma IgG recognition of IEs after Saimiri brain endothelial cell selection has not been reported, but domains from VAR1CSA do not show the expected VSAPAM-type sex-specific and parity-dependent IgG recognition (30).”
From Evidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria (2004) · cites this paper as [30]
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Cites
Adherence of Plasmodium falciparum to Chondroitin Sulfate A in the Human Placenta
Fried, M., & Duffy, P. E. (1996) · Science · doi:10.1126/science.272.5267.1502 · Cited by 1,108
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Malaria in pregnancy: pathogenesis and immunity
Rogerson, S. J., Hviid, L., Duffy, P. E., Leke, R. F., & Taylor, D. W. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70022-1 · Cited by 628
Self-citationEvidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria
Salanti, A., Dahlbäck, M., Turner, L., Nielsen, M. A., Barfod, L., Magistrado, P., Jensen, A. T. R., Lavstsen, T., Ofori, M. F., Marsh, K., et al. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20041579 · Cited by 604
Self-citationFrancis, S. E., Malkov, V. A., Oleinikov, A. V., Rossnagle, E., Wendler, J. P., Mutabingwa, T. K., Fried, M., & Duffy, P. E. (2007) · Infection and Immunity · doi:10.1128/iai.00635-07 · Cited by 65
Metadata
- Authors
- Jensen, A. T. R., Zornig, H. D., Buhmann, C., Salanti, A., Koram, K. A., Riley, E. M., Theander, T. G., Hviid, L., & Staalsoe, T.
- Affiliations
- University of Copenhagen (DK)
- Centre for Medical Parasitology, Copenhagen University Hospital (Rigshospitalet) and Institute for Medical Microbiology and Immunology, University of Copenhagen, Copenhagen, Denmark
- University of Ghana (GH)
- London School of Hygiene & Tropical Medicine (GB)
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 2003-07
- Volume
- 71
- Issue
- 7
- Pages
- 4193-4196
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- PMC
- PMC162013
- OpenAlex
- W2131622860
- Cited by
- 19
- References
- 1
- Citations by year
- 2022: 1 · 2019: 2 · 2018: 1 · 2012: 1
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Infection and Immunity (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Hematology › Blood groups and transfusion
- Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
- Keywords
- Plasmodium falciparum, malaria in pregnancy, variant surface antigens, var genes, chondroitin sulfate A, gene transcription
- MeSH terms
- Animals, Antibodies, Protozoan, Chondroitin Sulfates, Female, Humans, Immunoglobulin G, Male, Parity, Plasmodium falciparum, Pregnancy, Sex Factors, Pregnancy Complications, Parasitic, Protozoan Proteins, Malaria, Falciparum
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