The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Unique Transcriptome Signature of Mycobacterium tuberculosis in Pulmonary Tuberculosis
Open accessAbstract
Although tuberculosis remains a substantial global threat, the mechanisms that enable mycobacterial persistence and replication within the human host are ill defined. This study represents the first genome-wide expression analysis of Mycobacterium tuberculosis from clinical lung samples, which has enabled the identification of M. tuberculosis genes actively expressed during pulmonary tuberculosis. To obtain optimal information from our DNA array analyses, we analyzed the differentially expressed genes within the context of computationally inferred protein networks. Protein networks were constructed using functional linkages established by the Rosetta stone, phylogenetic profile, conserved gene neighbor, and operon computational methods. This combined approach revealed that during pulmonary tuberculosis, M. tuberculosis actively transcribes a number of genes involved in active fortification and evasion from host defense systems. These genes may provide targets for novel intervention strategies.
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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., et al. (1998) · Nature · doi:10.1038/31159 · Cited by 7,847
Detecting Protein Function and Protein-Protein Interactions from Genome Sequences
Marcotte, E. M., Pellegrini, M., Ng, H.-L., Rice, D. W., Yeates, T. O., & Eisenberg, D. (1999) · Science · doi:10.1126/science.285.5428.751 · Cited by 1,670
Self-citationTranscriptional Adaptation of Mycobacterium tuberculosis within Macrophages
Schnappinger, D., Ehrt, S., Voskuil, M. I., Liu, Y., Mangan, J. A., Monahan, I. M., Dolganov, G., Efron, B., Butcher, P. D., Nathan, C., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030846 · Cited by 1,420
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Self-citationCell‐Wall Alterations as an Attribute of Mycobacterium tuberculosis in Latent Infection
Seiler, P., Ulrichs, T., Bandermann, S., Pradl, L., Jörg, S., Krenn, V., Morawietz, L., Kaufmann, S. H. E., & Aichele, P. (2003) · The Journal of Infectious Diseases · doi:10.1086/378563 · Cited by 157
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Cited by
Genome plasticity of BCG and impact on vaccine efficacy
Brosch, R., Gordon, S. V., Garnier, T., Eiglmeier, K., Frigui, W., Valenti, P., Dos Santos, S., Duthoy, S., Lacroix, C., Garcia-Pelayo, C., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700869104 · Cited by 574
Deb, C., Lee, C.-M., Dubey, V. S., Daniel, J., Abomoelak, B., Sirakova, T. D., Pawar, S., Rogers, L., & Kolattukudy, P. E. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006077 · Cited by 440
Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum
Garton, N. J., Waddell, S. J., Sherratt, A. L., Lee, S.-M., Smith, R. J., Senner, C., Hinds, J., Rajakumar, K., Adegbola, R. A., Besra, G. S., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050075 · Cited by 435
Basic Concepts of Microarrays and Potential Applications in Clinical Microbiology
Miller, M. B., & Tang, Y.-W. (2009) · Clinical Microbiology Reviews · doi:10.1128/cmr.00019-09 · Cited by 419
Rohde, K. H., Abramovitch, R. B., & Russell, D. G. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.09.006 · Cited by 405
Metadata
- Authors
- Rachman, H., Strong, M., Ulrichs, T., Grode, L., Schuchhardt, J., Mollenkopf, H., Kosmiadi, G. A., Eisenberg, D., & Kaufmann, S. H. E.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 2006-02
- Volume
- 74
- Issue
- 2
- Pages
- 1233-1242
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W1963515263
- Cited by
- 243
- References
- 5
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- green
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- Rachman, H., Strong, M., Ulrichs, T., Grode, L., Schuchhardt, J., Mollenkopf, H., Kosmiadi, G. A., Eisenberg, D., & Kaufmann, S. H. E. (2006). Unique Transcriptome Signature of Mycobacterium tuberculosis in Pulmonary Tuberculosis. Infection and Immunity. https://doi.org/10.1128/iai.74.2.1233-1242.2006
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
