The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Tn916-induced mutations in the hemolysin determinant affecting virulence of Listeria monocytogenes
Open accessAbstract
A genetic determinant essential for hemolysin production by Listeria monocytogenes has been inactivated by insertion of transposon Tn916 into L. monocytogenes DNA. The transposon was transferred by means of conjugation of a streptomycin-resistant L. monocytogenes recipient strain with Streptococcus faecalis CG110 on membrane filters. Among the tetracycline-resistant transconjugants, mutants were detected which had lost hemolytic activity. When tested in a mouse model, these mutants appeared to have lost the virulence that characterizes the parental strain. An extracellular protein of 58,000 apparent molecular weight was eliminated in the nonhemolytic mutants. In some of the mutants, the decrease in the production of the 58,000-dalton protein was accompanied by the production of a new protein of 49,000 apparent molecular weight. Hemolytic revertants regained the hemolytic phenotype and virulence and produced the extracellular protein that characterizes the recipient strain. Hybridization studies with Tn916 DNA indicated that the transposon is present in EcoRI and HindIII fragments of the nonhemolytic mutants. Single copies of Tn916 were detected in the chromosomal DNA of two of the three nonhemolytic mutants that were studied in detail. In hemolytic, tetracycline-sensitive revertants Tn916 appeared to be completely excised from the chromosome.
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Cites
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,221
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Southern, E. M. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80083-0 · Cited by 32,249
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
CELLULAR RESISTANCE TO INFECTION
Mackaness, G. B. (1962) · The Journal of Experimental Medicine · doi:10.1084/jem.116.3.381 · Cited by 1,361
Genetic engineering in Vivo using translocatable drug-resistance elements
Kleckner, N. E., Roth, J. R., & Botstein, D. (1977) · Journal of Molecular Biology · doi:10.1016/0022-2836(77)90123-1 · Cited by 600
Franke, A. E., & Clewell, D. B. (1981) · Journal of Bacteriology · doi:10.1128/jb.145.1.494-502.1981 · Cited by 551
Gaillard, J. L., Berche, P., & Sansonetti, P. (1986) · Infection and Immunity · doi:10.1128/iai.52.1.50-55.1986 · Cited by 438
Gawron-Burke, C., & Clewell, D. B. (1984) · Journal of Bacteriology · doi:10.1128/jb.159.1.214-221.1984 · Cited by 261
Cited by
Role of hemolysin for the intracellular growth of Listeria monocytogenes.
Portnoy, D. A., Jacks, P. S., & Hinrichs, D. J. (1988) · The Journal of experimental medicine · doi:10.1084/jem.167.4.1459 · Cited by 871
Gaillard, J.-L., Berche, P., Frehel, C., Gouln, E., & Cossart, P. (1991) · Cell · doi:10.1016/0092-8674(91)90009-n · Cited by 835
Listeria monocytogenes — from saprophyte to intracellular pathogen
Freitag, N. E., Port, G. C., & Miner, M. D. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2171 · Cited by 577
Molecular determinants of Listeria monocytogenes pathogenesis
Portnoy, D. A., Chakraborty, T., Goebel, W., & Cossart, P. (1992) · Infection and Immunity · doi:10.1128/iai.60.4.1263-1267.1992 · Cited by 554
Self-citationCossart, P., Vicente, M. F., Mengaud, J., Baquero, F., Perez-Diaz, J. C., & Berche, P. (1989) · Infection and Immunity · doi:10.1128/iai.57.11.3629-3636.1989 · Cited by 434
Metadata
- Authors
- Kathariou, S., Metz, P., Hof, H., & Goebel, W.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1987-03
- Volume
- 169
- Issue
- 3
- Pages
- 1291-1297
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2143735644
- Cited by
- 340
- References
- 17
- FWCI
- 26.73
- Type
- journal article
- Language
- en
- Open access
- green
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- Kathariou, S., Metz, P., Hof, H., & Goebel, W. (1987). Tn916-induced mutations in the hemolysin determinant affecting virulence of Listeria monocytogenes. Journal of Bacteriology. https://doi.org/10.1128/jb.169.3.1291-1297.1987
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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