The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants
Open accessAbstract
Pheromone-responsive conjugative plasmids are unique to the species Enterococcus faecalis. Many pheromone-responsive plasmids, including those frequently isolated from sites of infection, express a novel cytolysin that possesses both hemolytic and bacteriocin activities. Further, this cytolysin has been shown to be a toxin in several disease models. In the present study, nucleotide sequence determination, mutagenesis, and complementation analysis were used to determine the organization of the E. faecalis plasmid pAD1 cytolysin determinant. Four open reading frames are required for expression of the cytolysin precursor (cylLL, cylLS, cylM, and cylB). The inferred products of two of these open reading frames, CyILL and CyILS, constitute the cytolysin precursor and bear structural resemblance to posttranslationally modified bacteriocins termed lantibiotics. Similarities between the organization of the E. faecalis cytolysin determinant and expression units for lantibiotics exist, indicating that the E. faecalis cytolysin represents a new branch of this class and is the first known to possess toxin activity.
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The role and application of enterococci in food and health
Foulquié Moreno, M. R., Sarantinopoulos, P., Tsakalidou, E., & De Vuyst, L. (2006) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2005.06.026 · Cited by 1,080
Preservation and Fermentation: Past, Present and Future
Paul Ross, R., Morgan, S., & Hill, C. (2002) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00174-5 · Cited by 942
Enterococci as probiotics and their implications in food safety
Franz, C. M. A. P., Huch, M., Abriouel, H., Holzapfel, W., & Gálvez, A. (2011) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2011.08.014 · Cited by 788
Biosynthesis and Mode of Action of Lantibiotics
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CELL-CELL COMMUNICATION IN GRAM-POSITIVE BACTERIA
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Metadata
- Authors
- Gilmore, M. S., Segarra, R. A., Booth, M. C., Bogie, C. P., Hall, L. R., & Clewell, D. B.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1994-12
- Volume
- 176
- Issue
- 23
- Pages
- 7335-7344
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W1763808251
- Cited by
- 280
- References
- 40
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants. https://app.cochat.ai/papers/10.1128/jb.176.23.7335-7344.1994
- The paper
- Gilmore, M. S., Segarra, R. A., Booth, M. C., Bogie, C. P., Hall, L. R., & Clewell, D. B. (1994). Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants. Journal of Bacteriology. https://doi.org/10.1128/jb.176.23.7335-7344.1994
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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