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Lipid II-Mediated Pore Formation by the Peptide Antibiotic Nisin: a Black Lipid Membrane Study
Open accessAbstract
The antibiotic peptide nisin is the first known lantibiotic that uses a docking molecule within the bacterial cytoplasmic membrane for pore formation. Through specific interaction with the cell wall precursor lipid II, nisin forms defined pores which are stable for seconds and have pore diameters of 2 to 2.5 nm.
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Citations
Cited by
Insights into the mode of action of chitosan as an antibacterial compound.
Raafat, D., von Bargen, K., Haas, A., & Sahl, H.-G. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00453-08 · Cited by 888
Self-citationBiosynthesis and Mode of Action of Lantibiotics
Chatterjee, C., Paul, M., Xie, L., & van der Donk, W. A. (2005) · Chemical Reviews · doi:10.1021/cr030105v · Cited by 718
Lantibiotics: Peptides of Diverse Structure and Function
Willey, J. M., & van der Donk, W. A. (2007) · Annual Review of Microbiology · doi:10.1146/annurev.micro.61.080706.093501 · Cited by 621
Effects of Bacteriocins on Methicillin-Resistant Staphylococcus aureus Biofilm
Okuda, K.-I., Zendo, T., Sugimoto, S., Iwase, T., Tajima, A., Yamada, S., Sonomoto, K., & Mizunoe, Y. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00888-13 · Cited by 305
Assembly and Stability of Nisin−Lipid II Pores
Hasper, H. E., de Kruijff, B., & Breukink, E. (2004) · Biochemistry · doi:10.1021/bi049476b · Cited by 271
Metadata
- Authors
- Wiedemann, I., Benz, R., & Sahl, H.-G.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 2004-05-15
- Volume
- 186
- Issue
- 10
- Pages
- 3259-3261
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2037701752
- Cited by
- 182
- References
- 0
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Lipid II-Mediated Pore Formation by the Peptide Antibiotic Nisin: a Black Lipid Membrane Study. https://app.cochat.ai/papers/10.1128/jb.186.10.3259-3261.2004
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- Wiedemann, I., Benz, R., & Sahl, H.-G. (2004). Lipid II-Mediated Pore Formation by the Peptide Antibiotic Nisin: a Black Lipid Membrane Study. Journal of Bacteriology. https://doi.org/10.1128/jb.186.10.3259-3261.2004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.