Cited by 60Bacterial Identification and Susceptibility TestingStreptococcal Infections and TreatmentsClinical Laboratory Practices and Quality Control

Automated Detection of Streptococcus pyogenes Pharyngitis by Use of Colorex Strep A CHROMagar and WASPLab Artificial Intelligence Chromogenic Detection Module Software

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Van, Tam T., Mata, Kenneth, Dien Bard, Jennifer·2019·Journal of Clinical Microbiology

Abstract

Colorex Strep A agar (CHROMagar, Paris, France) was evaluated with PhenoMATRIX chromogenic detection module (CDM) software (Copan Diagnostics Inc., Murrieta, CA) to detect group A Streptococcus (GAS) from throat specimens. The software results were compared to those of manual plate image reading. In addition, GAS PCR testing was performed on all specimens.

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  1. [1]Hing E, Cherry DK, Woodwell DA 2006 National Ambulatory Medical Care Survey: 2004 summary. Adv Data 374: 1– 33. 16841616
  2. [2]Bisno AL 2001 Acute pharyngitis. N Engl J Med 344: 205– 211. doi: 10.1056/NEJM200101183440308. 11172144 · DOI
  3. [3]Group E, Pelucchi C, Grigoryan L, Galeone C, Esposito S, Huovinen P, Little P, Verheij T 2012 Guideline for the management of acute sore throat. Clin Microbiol Infect 18(Suppl 1): 1– 28. doi: 10.1111/j.1469-0691.2012.03766.x. 22432746 · DOI
  4. [4]McIsaac WJ, Goel V, To T, Low DE 2000 The validity of a sore throat score in family practice. CMAJ 163: 811– 815. 11033707 PMC80502
  5. [5]Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, Martin JM, Van Beneden C 2012 Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 55: e86– e102. doi: 10.1093/cid/cis629. 22965026 PMC7108032 · DOI
  6. [6]Lieberman D, Shvartzman P, Korsonsky I, Lieberman D 2001 Aetiology of respiratory tract infections: clinical assessment versus serological tests. Br J Gen Pract 51: 998– 1000. 11766873 PMC1314193
  7. [7]Mirza A, Wludyka P, Chiu TT, Rathore MH 2007 Throat culture is necessary after negative rapid antigen detection tests. Clin Pediatr (Phila) 46: 241– 246. doi: 10.1177/0009922806290219. 17416880 · DOI
  8. [9]Faron ML, Buchan BW, Vismara C, Lacchini C, Bielli A, Gesu G, Liebregts T, van Bree A, Jansz A, Soucy G, Korver J, Ledeboer NA 2016 Automated scoring of chromogenic media for detection of methicillin-resistant Staphylococcus aureus by use of WASPLab image analysis software. J Clin Microbiol 54: 620– 624. doi: 10.1128/JCM.02778-15. 26719443 PMC4767952 · DOI · Paper page
  9. [10]Van TT, Mestas J, Dien Bard J 2018 Molecular testing for detection of groups A, C, and G β-hemolytic streptococci in pharyngeal samples from children. J Appl Lab Med 3: 429– 437. doi: 10.1373/jalm.2018.026104. 33636907 · DOI
  10. [11]Gaskin M, Korver J, Yamamura D 2019 Validation and implementation of Colorex™ CHROMagar™ Strep A agar on WASP™WASPLab™ for screening for Streptococcus pyogenes using the ESwab™, poster CPHM-872 In Proceedings of ASM Microbe 2019. American Society for Microbiology, Washington, DC.
  11. [12]Keyak CC 2019 Digital detection and the use of artificial intelligence to detect group A Streptococcus using a chromogenic agar, poster CPHM-879 In Proceedings of ASM Microbe 2019. American Society for Microbiology, Washington, DC.
  12. [13]Church DL, Baxter H, Lloyd T, Larios O, Gregson DB 2017 Evaluation of StrepBSelect chromogenic medium and the Fast-Track Diagnostics group B streptococcus (GBS) real-time PCR assay compared to routine culture for detection of GBS during antepartum screening. J Clin Microbiol 55: 2137– 2142. doi: 10.1128/JCM.00043-17. 28446575 PMC5483915 · DOI
  13. [14]Rindala S, Jean-Ralph Z, Carbonnelle E, Lescat M 2019 Aerobic bacteria as Escherichia coli can survive in ESwab medium after a 3 month-freezing at −80°C but not after multiple thawing. bioRxiv 537647. doi: 10.1101/537647. · DOI
  14. [15]Hubbard K, Pellar G, Emanuel P 2011 Suitability of commercial transport media for biological pathogens under nonideal conditions. Int J Microbiol 2011: 463096. doi: 10.1155/2011/463096. 22121364 PMC3206327 · DOI

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Authors
Van, T. T., Mata, K., & Dien Bard, J.
Affiliations
  • University of California, Los Angeles (US)
  • Children's Hospital Los Angeles (US)
  • Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, California, USA
Venue
Journal of Clinical Microbiology
Published
2019-11
Volume
57
Issue
11
ISSN
  • 0095-1137 (ISSN-L)
  • 1098-660X
OpenAlex
W2969881032
Cited by
60
References
1
Citations by year
2026: 8 · 2025: 6 · 2024: 13 · 2023: 14 · 2022: 6 · 2021: 4 · 2020: 9
FWCI
3.28
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Microbiology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Streptococcal Infections and Treatments
  • Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
Keywords
Streptococcus pyogenes, group A streptococcal pharyngitis, automated detection, chromogenic agar, beta-hemolysis, PCR testing, diagnostic accuracy
MeSH terms
Agar, Artificial Intelligence, Bacteriological Techniques, Child, Chromogenic Compounds, Humans, Pharyngitis, Pharynx, Sensitivity and Specificity, Software, Streptococcal Infections, Streptococcus pyogenes, Automation, Laboratory

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