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Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1
Open accessAbstract
Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.
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Citations
Cited by
Carey-Ann, B. D., & Carroll, K. C. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00016-13 · Cited by 423
Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis
Karen C., C., & John G., B. (2011) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090110-102824 · Cited by 233
Clostridium difficile infection: an update on epidemiology, risk factors, and therapeutic options
Lo Vecchio, A., & Zacur, G. M. (2012) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e32834bc9a9 · Cited by 183
Metadata
- Authors
- Åkerlund, T., Persson, I., Unemo, M., Norén, T., Svenungsson, B., Wullt, M., & Burman, L. G.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2008-04
- Volume
- 46
- Issue
- 4
- Pages
- 1530-1533
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2141951202
- Cited by
- 223
- References
- 0
- FWCI
- 14.04
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1. https://app.cochat.ai/papers/10.1128/jcm.01964-07
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- Åkerlund, T., Persson, I., Unemo, M., Norén, T., Svenungsson, B., Wullt, M., & Burman, L. G. (2008). Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.01964-07
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
