Comparison of the Xpert MTB/RIF Test with an IS 6110 -TaqMan Real-Time PCR Assay for Direct Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens

Armand, Sylvie; Vanhuls, Pascale; Delcroix, Guy; Courcol, René; Lemaître, Nadine

doi:10.1128/jcm.02157-10

Comparison of the Xpert MTB/RIF Test with an IS 6110 -TaqMan Real-Time PCR Assay for Direct Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens

The sensitivities of the Xpert MTB/RIF test and an in-house IS 6110 -based real-time PCR using TaqMan probes (IS 6110 -TaqMan assay) for the detection of Mycobacterium tuberculosis complex (MTBC) DNA were compared by use of 117 clinical specimens (97 culture positive and 20 culture negative for M…