The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Evidence of Uncultivated Bacteria in the Adult Female Bladder
Open accessAbstract
Clinical urine specimens are usually considered to be sterile when they do not yield uropathogens using standard clinical cultivation procedures. Our aim was to test if the adult female bladder might contain bacteria that are not identified by these routine procedures. An additional aim was to identify and recommend the appropriate urine collection method for the study of bacterial communities in the female bladder. Consenting participants who were free of known urinary tract infection provided urine samples by voided, transurethral, and/or suprapubic collection methods. The presence of bacteria in these samples was assessed by bacterial culture, light microscopy, and 16S rRNA gene sequencing. Bacteria that are not or cannot be routinely cultivated (hereinafter called uncultivated bacteria) were common in voided urine, urine collected by transurethral catheter (TUC), and urine collected by suprapubic aspirate (SPA), regardless of whether the subjects had urinary symptoms. Voided urine samples contained mixtures of urinary and genital tract bacteria. Communities identified in parallel urine samples collected by TUC and SPA were similar. Uncultivated bacteria are clearly present in the bladders of some women. It remains unclear if these bacteria are viable and/or if their presence is relevant to idiopathic urinary tract conditions.
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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Altschul, S. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.17.3389 · Cited by 73,302
Gupta, K., Hooton, T. M., Naber, K. G., Wullt, B., Colgan, R., Miller, L. G., Moran, G. J., Nicolle, L. E., Raz, R., Schaeffer, A. J., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq257 · Cited by 3,038
Molecular Identification of Bacteria Associated with Bacterial Vaginosis
Fredricks, D. N., Fiedler, T. L., & Marrazzo, J. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043802 · Cited by 1,303
Laboratory Diagnosis of Urinary Tract Infections in Adult Patients
Wilson, M. L., & Gaido, L. (2004) · Clinical Infectious Diseases · doi:10.1086/383029 · Cited by 680
Bailey, M. T., Dowd, S. E., Parry, N. M. A., Galley, J. D., Schauer, D. B., & Lyte, M. (2010) · Infection and Immunity · doi:10.1128/iai.00862-09 · Cited by 335
Barber, M. D., Spino, C., Janz, N. K., Brubaker, L., Nygaard, I., Nager, C. W., & Wheeler, T. L. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2009.02.007 · Cited by 155
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Cited by
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Urbaniak, C., Cummins, J., Brackstone, M., Macklaim, J. M., Gloor, G. B., Baban, C. K., Scott, L., O'Hanlon, D. M., Burton, J. P., Francis, K. P., et al. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.00242-14 · Cited by 552
Sequencing-based methods and resources to study antimicrobial resistance
Boolchandani, M., D’Souza, A. W., & Dantas, G. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0108-4 · Cited by 522
The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults
Lewis, D. A., Brown, R., Williams, J., White, P., Jacobson, S. K., Marchesi, J. R., & Drake, M. J. (2013) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2013.00041 · Cited by 382
Urinary tract infections: pathogenesis, host susceptibility and emerging therapeutics
Timm, M. R., Russell, S. K., & Hultgren, S. J. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-024-01092-4 · Cited by 190
The Etiology and Management of Recurrent Urinary Tract Infections in Postmenopausal Women
Jung, C., & Brubaker, L. (2019) · Climacteric · doi:10.1080/13697137.2018.1551871 · Cited by 169
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Metadata
- Authors
- Wolfe, A. J., Toh, E., Shibata, N., Rong, R., Kenton, K., FitzGerald, M., Mueller, E. R., Schreckenberger, P., Dong, Q., Nelson, D. E., & Brubaker, L.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2012-04
- Volume
- 50
- Issue
- 4
- Pages
- 1376-1383
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W1967961996
- Cited by
- 671
- References
- 6
- FWCI
- 14.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Wolfe, A. J., Toh, E., Shibata, N., Rong, R., Kenton, K., FitzGerald, M., Mueller, E. R., Schreckenberger, P., Dong, Q., Nelson, D. E., & Brubaker, L. (2012). Evidence of Uncultivated Bacteria in the Adult Female Bladder. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.05852-11
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
