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BacT/Alert: an automated colorimetric microbial detection system
Open accessAbstract
BacT/Alert (Organon Teknika Corp., Durham, N.C.) is an automated microbial detection system based on the colorimetric detection of CO2 produced by growing microorganisms. Results of an evaluation of the media, sensor, detection system, and detection algorithm indicate that the system reliably grows and detects a wide variety of bacteria and fungi. Results of a limited pilot clinical trial with a prototype research instrument indicate that the system is comparable to the radiometric BACTEC 460 system in its ability to grow and detect microorganisms in blood. On the basis of these initial findings, large-scale clinical trials comparing BacT/Alert with other commercial microbial detection systems appear warranted.
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Citations
Cited by
Update on detection of bacteremia and fungemia
Reimer, L. G., Wilson, M. L., & Weinstein, M. P. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.3.444 · Cited by 482
Self-citationVolume of blood required to detect common neonatal pathogens
Schelonka, R. L., Chai, M. K., Yoder, B. A., Hensley, D., Brockett, R. M., & Ascher, D. P. (1996) · The Journal of Pediatrics · doi:10.1016/s0022-3476(96)70254-8 · Cited by 447
Connell, T. G., Rele, M., Cowley, D., Buttery, J. P., & Curtis, N. (2007) · Pediatrics · doi:10.1542/peds.2006-0440 · Cited by 401
CO2 Acts as a Signalling Molecule in Populations of the Fungal Pathogen Candida albicans
Hall, R. A., De Sordi, L., MacCallum, D. M., Topal, H., Eaton, R., Bloor, J. W., Robinson, G. K., Levin, L. R., Buck, J., Wang, Y., et al. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001193 · Cited by 126
Parveen, S., Kaur, S., David, S. A. W., Kenney, J. L., McCormick, W. M., & Gupta, R. K. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.08.055 · Cited by 81
Metadata
- Authors
- Thorpe, T. C., Wilson, M. L., Turner, J. E., DiGuiseppi, J. L., Willert, M., Mirrett, S., & Reller, L. B.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1990-07
- Volume
- 28
- Issue
- 7
- Pages
- 1608-1612
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2010084163
- Cited by
- 265
- References
- 0
- FWCI
- 3.15
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: BacT/Alert: an automated colorimetric microbial detection system. https://app.cochat.ai/papers/10.1128/jcm.28.7.1608-1612.1990
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- Thorpe, T. C., Wilson, M. L., Turner, J. E., DiGuiseppi, J. L., Willert, M., Mirrett, S., & Reller, L. B. (1990). BacT/Alert: an automated colorimetric microbial detection system. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.28.7.1608-1612.1990
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
