The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Selective and differential medium for isolation of Clostridium difficile
Open accessAbstract
Clostridium difficile is a recognized cause of pseudomembranous (antimicrobial agent-associated) colitis and may be one of the causes of antimicrobial agent-induced diarrhea. A selective and differential agar medium that contains cycloserine, cefoxitin, fructose, and egg yolk (CCFA) was developed to facilitate the isolation of C. difficile from fecal specimens. Quantitative cultures of 16 stock strains of C. difficile on this medium (and on a medium containing cycloserine, fructose, and egg yolk) yielded counts equivalent to those obtained on blood agar; other media selective for clostridia, including Clostrisel agar, reinforced clostridial agar plus 0.2% para-cresol, and egg yolk-neomycin agar (the latter was inoculated with cultures subjected to prior heat shocking), were also tested and found to be inhibitory to the growth of C. difficile. Of 28 fecal or colostomy effluent specimens cultured on the above media, 14 yielded C. difficile. CCFA was found to be the most sensitive and selective of these media for the recovery of C. difficile. Colonies of C. difficile growing on CCFA had distinctive morphological and fluorescent properties which were sufficient for presumptive identification. CCFA should provide a rapid method for the screening of fecal specimens from patients with antimicrobial agent-associated diarrhea or colitis for C. difficile.
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Cites
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia
Bartlett, J. G., Chang, T. W., Gurwith, M., Gorbach, S. L., & Onderdonk, A. B. (1978) · New England Journal of Medicine · doi:10.1056/nejm197803092981003 · Cited by 1,374
Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters
Bartlett, J. G., Onderdonk, A. B., Cisneros, R. L., & Kasper, D. L. (1977) · Journal of Infectious Diseases · doi:10.1093/infdis/136.5.701 · Cited by 472
Clindamycin-Associated Colitis
Cohen, L. E. (1973) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1973.03220120045012 · Cited by 280
ÆTIOLOGY OF ANTIMICROBIAL-AGENT-ASSOCIATED COLITIS
Lance George, W., Goldstein, E. C., Sutter, V., Ludwig, S., & Finegold, S. (1978) · The Lancet · doi:10.1016/s0140-6736(78)93001-5 · Cited by 209
Self-citationClostridium difficile: isolation and characteristics (Plate VIII)
HAFIZ, S., & Oakley, C. L. (1976) · Journal of Medical Microbiology · doi:10.1099/00222615-9-2-129 · Cited by 146
George, W. L., Sutter, V. L., & Finegold, S. M. (1978) · Current Microbiology · doi:10.1007/bf02601709 · Cited by 123
Self-citationCLOSTRIDIUM DIFFICILE IN THE UROGENITAL TRACT OF MALES AND FEMALES
Hafiz, S., Morton, R. S., McEntegart, M. G., & Waitkins, S. A. (1975) · The Lancet · doi:10.1016/s0140-6736(75)91489-0 · Cited by 79
Cited by
Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: A prospective study
Surawicz, C. M., Elmer, G. W., Speelman, P., McFarland, L. V., Chinn, J., & Van Belle, G. (1989) · Gastroenterology · doi:10.1016/0016-5085(89)91613-2 · Cited by 573
Carey-Ann, B. D., & Carroll, K. C. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00016-13 · Cited by 423
Johnson, S., Gerding, D. N., Olson, M. M., Weiler, M. D., Hughes, R. A., Clabots, C. R., & Peterson, L. R. (1990) · The American Journal of Medicine · doi:10.1016/0002-9343(90)90462-m · Cited by 317
Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis
Karen C., C., & John G., B. (2011) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090110-102824 · Cited by 233
Shilling, M., Matt, L., Rubin, E., Visitacion, M. P., Haller, N. A., Grey, S. F., & Woolverton, C. J. (2013) · Journal of Medicinal Food · doi:10.1089/jmf.2012.0303 · Cited by 143
Metadata
- Authors
- George, W. L., Sutter, V. L., Citron, D., & Finegold, S. M.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1979-02
- Volume
- 9
- Issue
- 2
- Pages
- 214-219
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2130596438
- Cited by
- 632
- References
- 7
- FWCI
- 48.81
- Type
- journal article
- Language
- en
- Open access
- green
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- George, W. L., Sutter, V. L., Citron, D., & Finegold, S. M. (1979). Selective and differential medium for isolation of Clostridium difficile. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.9.2.214-219.1979
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
