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Cited by 117Animal Virus Infections StudiesZoonotic diseases and public healthViral gastroenteritis research and epidemiology

Identification of Multiple Novel Viruses, Including a Parvovirus and a Hepevirus, in Feces of Red Foxes

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Bodewes, Rogier, van der Giessen, Joke, Haagmans, Bart L., Osterhaus, Albert D. M. E., Smits, Saskia L.·2013·Journal of Virology
DOI 10.1128/jvi.00568-13PMC PMC3700315
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Abstract

Red foxes ( Vulpes vulpes ) are the most widespread members of the order of Carnivora . Since they often live in (peri)urban areas, they are a potential reservoir of viruses that transmit from wildlife to humans or domestic animals. Here we evaluated the fecal viral microbiome of 13 red foxes by random PCR in combination with next-generation sequencing. Various novel viruses, including a parvovirus, bocavirus, adeno-associated virus, hepevirus, astroviruses, and picobirnaviruses, were identified.

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  • Hepeviridae cause hepatitis E in mammals and have been isolated from various domestic and wild animals including foxes in the Netherlands.

    “We discovered viral transcripts with some sequence similarity to the Hepeviridae that cause hepatitis E in mammals, which has already been isolated from various domestic and wild animals including foxes in the Netherlands (Meng 2010; Bodewes et al. 2013).”

    From Red fox viromes in urban and rural landscapes (2020) · cites this paper as Bodewes et al. 2013

    The paper reports hepatitis E viruses in domestic animals and identifies hepevirus sequences in feces from red foxes collected in the Netherlands (Abstract and study description; page not supplied). It did not isolate a virus or establish that the foxes were infected: it says the sequences might have come from their prey. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

  • The hepevirus detected in this study was phylogenetically distinct from the fox hepatitis E virus previously detected.

    “In contrast, the hepevirus detected here was phylogenetically distinct from the fox hepatitis E virus previously detected (Bodewes et al. 2013) and instead was more closely related to hepeviruses detected in freshwater mussels and a house mouse.”

    From Red fox viromes in urban and rural landscapes (2020) · cites this paper as Bodewes et al. 2013

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Cited by

Sorted by citations

Authors
Bodewes, R., van der Giessen, J., Haagmans, B. L., Osterhaus, A. D. M. E., & Smits, S. L.
Affiliations
  • Erasmus MC (NL)
  • National Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control, Bilthoven, The Netherlands
ORCID
Venue
Journal of Virology
Publisher
American Society for Microbiology
Published
2013-07
Volume
87
Issue
13
Pages
7758-7764
ISSN
  • 0022-538X (ISSN-L)
  • 1098-5514
DOI
10.1128/jvi.00568-13
PMC
PMC3700315
OpenAlex
W2016522317
Cited by
117
References
56
Citations by year
2026: 3 · 2025: 5 · 2024: 3 · 2023: 7 · 2022: 6 · 2021: 8 · 2020: 12 · 2019: 7 · 2018: 12 · 2017: 9 · 2016: 5 · 2015: 13 · 2014: 21 · 2013: 5
FWCI
24.28
Type
journal article
Language
en
Open access
Licence
journals.asm.org/non-commercial-tdm-license (tdm)
Locations
  • Journal of Virology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
  • Utrecht University Repository (Utrecht University) (submittedVersion)
  • Rivm Repository (Netherlands National Institute for Public Health and the Environment) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
  • Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
Keywords
red fox, novel virus, parvovirus, bocavirus, adeno-associated virus, astrovirus, wildlife reservoirs, zoonotic transmission, viral metagenomics
MeSH terms
Amino Acid Sequence, Animals, Base Sequence, Disease Reservoirs, Feces, Foxes, Models, Genetic, Molecular Sequence Data, Phylogeny, Species Specificity, Likelihood Functions, Polymerase Chain Reaction, Sequence Analysis, DNA, Parvovirus, Picobirnavirus, Astroviridae, Hepevirus, Metagenome

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