The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1
Open accessAbstract
We isolated and molecularly cloned a human immunodeficiency virus type 1 (HIV-1) strain (89.6) which is unusual because it is both macrophage-tropic and extremely cytopathic in lymphocytes. Moreover, this is the first well-characterized infectious molecularly cloned macrophage-tropic HIV-1 strain derived from peripheral blood. HIV-1 89.6 differs markedly from other macrophage-tropic isolates within the envelope V3 region, which is important in determining cell tropism and cytopathicity. HIV-1 89.6 may thus represent a transitional isolate between noncytopathic macrophage-tropic viruses and cytopathic lymphocyte-tropic viruses.
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Cites
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Metadata
- Authors
- Collman, R., Balliet, J. W., Gregory, S. A., Friedman, H., Kolson, D. L., Nathanson, N., & Srinivasan, A.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1992-12
- Volume
- 66
- Issue
- 12
- Pages
- 7517-7521
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1946734657
- Cited by
- 358
- References
- 24
- FWCI
- 2.77
- Type
- journal article
- Language
- en
- Open access
- green
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- Collman, R., Balliet, J. W., Gregory, S. A., Friedman, H., Kolson, D. L., Nathanson, N., & Srinivasan, A. (1992). An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. Journal of Virology. https://doi.org/10.1128/jvi.66.12.7517-7521.1992
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