The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Human cytomegalovirus IE1 and IE2 proteins block apoptosis
Open accessAbstract
Human cytomegalovirus-infected fibroblasts are resistant to the induction of apoptosis by superinfection with a mutant adenovirus unable to produce the viral E1B 19-kDa protein that normally causes an E1A protein-mediated apoptotic response. Two cytomegalovirus gene products that block apoptosis were identified. The IE1 and IE2 proteins each inhibit the induction of apoptosis by tumor necrosis factor alpha or by the E1B 19-kDa-protein-deficient adenovirus but not by irradiation with UV light. Our results suggest a new physiological role for the IE1 and IE2 proteins in the human cytomegalovirus replication cycle.
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Cites
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Gossen, M., & Bujard, H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5547 · Cited by 4,943 · cited 2×
“The adenovirus E1B 19-kDa-protein-expressing cell line, HE1B-19K, was generated by cotransfection of pUHG15-1neo (11) and pUHG19K into HeLa cells.”
Methodp53-Dependent apoptosis suppresses tumor growth and progression in vivo
Symonds, H., Krall, L., Remington, L., Saenz-Robles, M., Lowe, S., Jacks, T., & Van Dyke, T. (1994) · Cell · doi:10.1016/0092-8674(94)90534-7 · Cited by 880
Takayama, S., Sato, T., Krajewski, S., Kochel, K., Irie, S., Milian, J. A., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90410-7 · Cited by 857
Cited by
Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T., & Levine, A. J. (1998) · The EMBO Journal · doi:10.1093/emboj/17.2.554 · Cited by 610
Self-citationGoldmacher, V. S., Bartle, L. M., Skaletskaya, A., Dionne, C. A., Kedersha, N. L., Vater, C. A., Han, J.-W., Lutz, R. J., Watanabe, S., McFarland, E. D. C., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12536 · Cited by 423
The Story of Human Cytomegalovirus and Cancer: Increasing Evidence and Open Questions
Michaelis, M., Doerr, H. W., & Cinatl, J. (2009) · Neoplasia · doi:10.1593/neo.81178 · Cited by 293
Cristea, I. M., Moorman, N. J., Terhune, S. S., Cuevas, C. D., O'Keefe, E. S., Rout, M. P., Chait, B. T., & Shenk, T. (2010) · Journal of Virology · doi:10.1128/jvi.00139-10 · Cited by 155
Self-citationKoyuncu, E., Purdy, J. G., Rabinowitz, J. D., & Shenk, T. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003333 · Cited by 114
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Metadata
- Authors
- Zhu, H., Shen, Y., & Shenk, T.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1995-12
- Volume
- 69
- Issue
- 12
- Pages
- 7960-7970
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1623819487
- Cited by
- 468
- References
- 4
- FWCI
- 21.52
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhu, H., Shen, Y., & Shenk, T. (1995). Human cytomegalovirus IE1 and IE2 proteins block apoptosis. Journal of Virology. https://doi.org/10.1128/jvi.69.12.7960-7970.1995
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
