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Cited by 311

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA

Open access
Blyn, L B, Towner, J S, Semler, B L, Ehrenfeld, E·1997·Journal of Virology

Abstract

Poly(rC) binding protein 2 (PCBP2) is one of several cellular proteins that interact specifically with a major stem-loop domain in the poliovirus internal ribosome entry site. HeLa cell extracts subjected to stem-loop IV RNA affinity chromatography were depleted of all detectable PCBP2. Such extracts were unable to efficiently translate poliovirus RNA, although extracts recovered from control columns of matrix unlinked to RNA retained full translation activity. Both translation and production of infectious progeny virus were restored in the PCBP2-depleted extracts by addition of recombinant PCBP2, but not by PCBP1, which is a closely related member of the protein family. The data show that PCBP2 is an essential factor, which is required for efficient translation of poliovirus RNA in HeLa cells.

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Crossref · 10.1128/jvi.71.8.6243-6246.1997

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Metadata

Authors
Blyn, L. B., Towner, J. S., Semler, B. L., & Ehrenfeld, E.
Venue
Journal of Virology
Published
1997-08
Volume
71
Issue
8
Pages
6243-6246
ISSN
  • 0022-538X (ISSN-L)
  • 1098-5514
OpenAlex
W2098270395
Cited by
311
References
1
FWCI
5.29
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. https://app.cochat.ai/papers/10.1128/jvi.71.8.6243-6246.1997
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Blyn, L. B., Towner, J. S., Semler, B. L., & Ehrenfeld, E. (1997). Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. Journal of Virology. https://doi.org/10.1128/jvi.71.8.6243-6246.1997

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