The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Canine and Feline Parvoviruses Can Use Human or Feline Transferrin Receptors To Bind, Enter, and Infect Cells
Open accessAbstract
Canine parvovirus (CPV) enters and infects cells by a dynamin-dependent, clathrin-mediated endocytic pathway, and viral capsids colocalize with transferrin in perinuclear vesicles of cells shortly after entry (J. S. L. Parker and C. R. Parrish, J. Virol. 74:1919–1930, 2000). Here we report that CPV and feline panleukopenia virus (FPV), a closely related parvovirus, bind to the human and feline transferrin receptors (TfRs) and use these receptors to enter and infect cells. Capsids did not detectably bind or enter quail QT35 cells or a Chinese hamster ovary (CHO) cell-derived cell line that lacks any TfR (TRVb cells). However, capsids bound and were endocytosed into QT35 cells and CHO-derived TRVb-1 cells that expressed the human TfR. TRVb-1 cells or TRVb cells transiently expressing the feline TfR were susceptible to infection by CPV and FPV, but the parental TRVb cells were not. We screened a panel of feline-mouse hybrid cells for susceptibility to FPV infection and found that only those cells that possessed feline chromosome C2 were susceptible. The feline TfR gene (TRFC) also mapped to feline chromosome C2. These data indicate that cell susceptibility for these viruses is determined by the TfR.
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Cites
Crystal Structure of the Ectodomain of Human Transferrin Receptor
Lawrence, C. M., Ray, S., Babyonyshev, M., Galluser, R., Borhani, D. W., & Harrison, S. C. (1999) · Science · doi:10.1126/science.286.5440.779 · Cited by 315
Cited by
A Viral Phospholipase A2 Is Required for Parvovirus Infectivity
Zádori, Z., Szelei, J., Lacoste, M.-C., Li, Y., Gariépy, S., Raymond, P., Allaire, M., Nabi, I. R., & Tijssen, P. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00031-4 · Cited by 518
Viral infection and iron metabolism
Drakesmith, H., & Prentice, A. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1930 · Cited by 469
Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses
Radoshitzky, S. R., Abraham, J., Spiropoulou, C. F., Kuhn, J. H., Nguyen, D., Li, W., Nagel, J., Schmidt, P. J., Nunberg, J. H., Andrews, N. C., et al. (2007) · Nature · doi:10.1038/nature05539 · Cited by 438
Intracellular trafficking of adeno-associated viral vectors
Ding, W., Zhang, L., Yan, Z., & Engelhardt, J. F. (2005) · Gene Therapy · doi:10.1038/sj.gt.3302527 · Cited by 251
Dual host–virus arms races shape an essential housekeeping protein
Demogines, A., Abraham, J., Choe, H., Farzan, M., & Sawyer, S. L. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001571 · Cited by 133
Metadata
- Authors
- Parker, J. S. L., Murphy, W. J., Wang, D., O'Brien, S. J., & Parrish, C. R.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 2001-04-15
- Volume
- 75
- Issue
- 8
- Pages
- 3896-3902
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W2135581681
- Cited by
- 254
- References
- 1
- FWCI
- 3.12
- Type
- journal article
- Language
- en
- Open access
- green
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- Parker, J. S. L., Murphy, W. J., Wang, D., O'Brien, S. J., & Parrish, C. R. (2001). Canine and Feline Parvoviruses Can Use Human or Feline Transferrin Receptors To Bind, Enter, and Infect Cells. Journal of Virology. https://doi.org/10.1128/jvi.75.8.3896-3902.2001
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