The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli
Open accessAbstract
The outer membrane is a major determinant of the intrinsic antibiotic resistance of Gram-negative bacteria. It is composed of both lipopolysaccharide (LPS) and phospholipid, and the synthesis of these lipid species must be balanced for the membrane to maintain its barrier function in blocking drug entry. In this study, we identified an essential protein of unknown function as a key new factor in modulating LPS synthesis in the model bacterium Escherichia coli . Our results provide novel insight into how this organism and most likely other Gram-negative bacteria maintain membrane homeostasis and their intrinsic resistance to antibiotics.
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Cites
Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes
Baym, M., Kryazhimskiy, S., Lieberman, T. D., Chung, H., Desai, M. M., & Kishony, R. (2015) · PLOS ONE · doi:10.1371/journal.pone.0128036 · Cited by 685
Cited by
Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane
Sabnis, A., Hagart, K. L., Klöckner, A., Becce, M., Evans, L. E., Furniss, R. C. D., Mavridou, D. A., Murphy, R., Stevens, M. M., Davies, J. C., et al. (2021) · eLife · doi:10.7554/elife.65836 · Cited by 389
SARS-CoV-2 exposure in wild white-tailed deer ( Odocoileus virginianus )
Chandler, J. C., Bevins, S. N., Ellis, J. W., Linder, T. J., Tell, R. M., Jenkins-Moore, M., Root, J. J., Lenoch, J. B., Robbe-Austerman, S., DeLiberto, T. J., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2114828118 · Cited by 283
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
Kishi, K. E., Kim, Y. S., Fukuda, M., Inoue, M., Kusakizako, T., Wang, P. Y., Ramakrishnan, C., Byrne, E. F. X., Thadhani, E., Paggi, J. M., et al. (2022) · Cell · doi:10.1016/j.cell.2022.01.007 · Cited by 149
The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage
O’Hara, B. J., Alam, M., & Ng, W.-L. (2022) · PLOS Genetics · doi:10.1371/journal.pgen.1010250 · Cited by 45
Jackson-Litteken, C. D., Di Venanzio, G., Le, N.-H., Scott, N. E., Djahanschiri, B., Distel, J. S., Pardue, E. J., Ebersberger, I., & Feldman, M. F. (2022) · mBio · doi:10.1128/mbio.00258-22 · Cited by 38
Metadata
- Authors
- Fivenson, E. M., & Bernhardt, T. G.
- Venue
- mBio
- Publisher
- American Society for Microbiology
- Published
- 2020-06-30
- Volume
- 11
- Issue
- 3
- ISSN
- 2150-7511 (ISSN-L)
- 2161-2129
- OpenAlex
- W3028082238
- Cited by
- 321
- References
- 1
- FWCI
- 24.99
- Type
- journal article
- Language
- en
- Open access
- gold
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- Fivenson, E. M., & Bernhardt, T. G. (2020). An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli. mBio. https://doi.org/10.1128/mbio.00939-20
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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