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Cited by 23Bacterial biofilms and quorum sensingBacterial Genetics and BiotechnologyPolyamine Metabolism and Applications

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The Histone H1-Like Protein AlgP Facilitates Even Spacing of Polyphosphate Granules in Pseudomonas aeruginosa

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Chawla, Ravi, Klupt, Steven, Patsalo, Vadim, Williamson, James R., Racki, Lisa R.·2022·mBio
DOI 10.1128/mbio.02463-21PMC PMC9239181

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Abstract

The mechanisms underpinning polyP’s pleiotropic effects on bacterial starvation physiology remain elusive. This simple polyanion’s lack of protein binding specificity has impeded validation of bona fide polyP-binding proteins.

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Metadata

Authors
Chawla, R., Klupt, S., Patsalo, V., Williamson, J. R., & Racki, L. R.
Affiliations
Scripps Research Institute (US)
Corresponding author
Racki, Lisa R.
ORCID
Venue
mBio
Publisher
American Society for Microbiology
Published
2022-06-28
Volume
13
Issue
3
Pages
e0246321-e0246321
ISSN
2150-7511 (ISSN-L)
DOI
10.1128/mbio.02463-21
PMC
PMC9239181
OpenAlex
W4226040427
Cited by
23
References
2
Citations by year
2026: 9 · 2025: 6 · 2024: 7 · 2022: 1
FWCI
1.14
Type
journal article
Language
en
Open access
Licence
Locations
  • mBio (publishedVersion, cc-by)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • Donald E. and Delia B. Baxter Foundation
  • HHS | NIH | National Institute of General Medical Sciences (R35-GM-136412)
  • Scripps Research (Startup)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
Keywords
polyphosphate granules, polyphosphate, Pseudomonas aeruginosa, bacterial starvation, alginate biosynthesis, cystic fibrosis, chronic infection, genome rearrangement, biofilm formation
MeSH terms
Alginates, Bacterial Proteins, DNA-Binding Proteins, Histones, Polyphosphates, Pseudomonas aeruginosa, Transcription Factors

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