Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

BRCA1 and BRCA2: different roles in a common pathway of genome protection

Roy, R., Chun, J., & Powell, S. N. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3181 · Cited by 1,555

XRCC3 promotes homology-directed repair of DNA damage in mammalian cellsPreprint

Pierce, A. J., Johnson, R. D., Thompson, L. H., & Jasin, M. (1999) · Genes & Development · doi:10.1101/gad.13.20.2633 · Cited by 1,384

Regulation of Homologous Recombination in Eukaryotes

Heyer, W.-D., Ehmsen, K. T., & Liu, J. (2010) · Annual Review of Genetics · doi:10.1146/annurev-genet-051710-150955 · Cited by 1,066

Chromosome Instability and Defective Recombinational Repair in Knockout Mutants of the Five Rad51 Paralogs

Takata, M., Sasaki, M. S., Tachiiri, S., Fukushima, T., Sonoda, E., Schild, D., Thompson, L. H., & Takeda, S. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.8.2858-2866.2001 · Cited by 523

Rad51 Recombinase and Recombination Mediators

Sung, P., Krejčí, L., Komen, S. V., & Sehorn, M. G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300027200 · Cited by 446

Recombinational DNA repair and human disease

Thompson, L. H., & Schild, D. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(02)00224-5 · Cited by 417

Identification and purification of two distinct complexes containing the five RAD51 paralogsPreprint

Masson, J., Tarsounas, M., Stasiak, A. Z., Stasiak, A., Punatar, R. S., McIlwraith, M. J., Benson, F. E., & West, S. C. (2001) · Genes & Development · doi:10.1101/gad.947001 · Cited by 395

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

Feng, Z., Scott, S. P., Bussen, W., Sharma, G. G., Guo, G., Pandita, T. K., & Powell, S. N. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010959107 · Cited by 346

Chk2 Phosphorylation of BRCA1 Regulates DNA Double-Strand Break Repair

Zhang, J., Willers, H., Feng, Z., Ghosh, J. C., Kim, S., Weaver, D. T., Chung, J. H., Powell, S. N., & Xia, F. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.2.708-718.2004 · Cited by 323

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsPreprint

Hu, Y., Raynard, S. J., Sehorn, M. G., Lu, X., Bussen, W., Zheng, L., Stark, J. M., Barnes, E. L., Chi, P., Janščák, P., et al. (2007) · Genes & Development · doi:10.1101/gad.1609107 · Cited by 322

Rice RAD 51 paralogs play essential roles in somatic homologous recombination for DNA repair

Xu, Z., Zhang, J., Xu, M., Ji, W., Yu, M., Tao, Y., Gong, Z., Gu, M., & Yu, H. (2018) · The Plant Journal · doi:10.1111/tpj.13949 · Cited by 19

The RAD52 S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations

Adamson, A. W., Ding, Y. C., Mendez‐Dorantes, C., Bailis, A. M., Stark, J. M., & Neuhausen, S. L. (2020) · Molecular Oncology · doi:10.1002/1878-0261.12665 · Cited by 19

RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases

Guh, C.-L., Lei, K., Chen, Y., Jiang, Y., Chang, H.-Y., Liaw, H., Li, H., Yen, H., & Chi, P. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad856 · Cited by 18

DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells

Liu, S., Wang, Z., Shah, S. B., Chang, C., Ai, M., Nguyen, T., Xiang, R., & Wu, X. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102770 · Cited by 14

Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies

Balboni, B., Rinaldi, F., Previtali, V., Ciamarone, A., Girotto, S., & Cavalli, A. (2023) · Cancers · doi:10.3390/cancers15061817 · Cited by 20

RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines

Lee, P. S., Fang, J., Jessop, L., Myers, T. A., Raj, P., Hu, N., Wang, C., Taylor, P. R., Wang, J., Khan, J., et al. (2014) · Breast Cancer Basic and Clinical Research · doi:10.4137/bcbcr.s17766 · Cited by 17

DNA Double Strand Break Repair - Related Synthetic Lethality

Toma, M. M., Skórski, T., & Śliwiński, T. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180201114306 · Cited by 17

Identification of small molecule inhibitors of RAD52 for breast cancer therapy: in silico approach

Kumar, M., Dubey, R., Shukla, P., Dayal, D., Chaubey, K. K., Tsai, L.-W., & Kumar, S. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2220822 · Cited by 16

Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells

Yang, Q., Li, Y., Sun, R., & Li, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.637825 · Cited by 16

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C

Hu, C., Nagaraj, A. B., Shimelis, H., Montalban, G., Lee, K. Y., Huang, H., Lumby, C. A., Na, J., Susswein, L. R., Roberts, M. E., et al. (2023) · Cancer Research · doi:10.1158/0008-5472.can-22-2319 · Cited by 15

Biochemical Mechanisms of Genetic Recombination and DNA Repair

Raina, V. B., Jessop, A. M., & Greene, E. C. (2025) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-083024-113931 · Cited by 14

C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair

Zhou, Z., Yang, H., Liang, X., Zhou, T., Zhang, T., Yang, Y., Wang, J., & Wang, W. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112907 · Cited by 14

Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells

Carley, A. C., Jalan, M., Subramanyam, S., Roy, R., Borgstahl, G. E. O., & Powell, S. N. (2021) · Molecular and Cellular Biology · doi:10.1128/mcb.00524-21 · Cited by 13

Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility GeneXRCC2

Hilbers, F., Luijsterburg, M. S., Wiegant, W. W., Meijers, C. M., Völker-Albert, M. C., Boonen, R. A. C. M., van Asperen, C. J., Devilee, P., & van Attikum, H. (2016) · Human Mutation · doi:10.1002/humu.23019 · Cited by 15

MiRNA-binding site functional polymorphisms in DNA repair genes RAD51, RAD52, and XRCC2 and breast cancer risk in Chinese population

Cao, J., Luo, C., Peng, R., Guo, Q., Wang, K., Wang, P., Ye, H., & Song, C. (2016) · Tumor Biology · doi:10.1007/s13277-016-5459-2 · Cited by 14

Novel protective and risk loci in hip dysplasia in German Shepherds

Mikkola, L., Holopainen, S., Lappalainen, A. K., Pessa‐Morikawa, T., Augustine, T. J. P., Arumilli, M., Hytönen, M. K., Hakosalo, O., Lohi, H., & Iivanainen, A. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008197 · Cited by 17

XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase

Sharma, A. B., Erasimus, H., Pinto, L., Caron, M., Gopaul, D., Peterlini, T., Neumann, K., Nazarov, P. V., Fritah, S., Klink, B., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab785 · Cited by 15

RADA-dependent branch migration has a predominant role in plant mitochondria and its defect leads to mtDNA instability and cell cycle arrest

Chevigny, N., Weber‐Lotfi, F., Blevenec, A. L., Nadiras, C., Fertet, A., Bichara, M., Erhardt, M., Dietrich, A., Raynaud, C., & Gualberto, J. M. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010202 · Cited by 13

Breast Cancer and Breast Reconstruction

Krupp, S. S. (1983) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-198307000-00029 · Cited by 13

The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population

Alenezi, W. M., Milano, L., Fierheller, C. T., Serruya, C., Revil, T., Oros, K. K., Behl, S., Arcand, S. L., Nayar, P., Spiegelman, D., et al. (2022) · Cancers · doi:10.3390/cancers14092251 · Cited by 12

XRCC2 (X-ray repair cross complementing 2)

Andreassen, P. R., & Hanenberg, H. (2019) · Atlas of Genetics and Cytogenetics in Oncology and Haematology · doi:10.4267/2042/69759 · Cited by 12

Homologous recombination defects and how they affect replication fork maintenance

Son, M. Y., & Hasty, P. (2018) · Global Medical Genetics · doi:10.3934/genet.2018.4.192 · Cited by 14

Rad51C-ATXN7 fusion gene expression in colorectal tumors

Kalvala, A., Gao, L., Aguila, B., Dotts, K., Rahman, M. A., Nana-Sinkam, S. P., Zhou, X., Wang, Q.-E., Amann, J. M., Otterson, G. A., et al. (2016) · Molecular Cancer · doi:10.1186/s12943-016-0527-1 · Cited by 12

Increased single-strand annealing rather than non-homologous end-joining predicts hereditary ovarian carcinoma

Deniz, M., Romashova, T., Kostezka, S., Faul, A., Gundelach, T., Moreno‐Villanueva, M., Janni, W., Friedl, T. W. P., & Wiesmüller, L. (2017) · Oncotarget · doi:10.18632/oncotarget.21720 · Cited by 11

A dominant RAD51C pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect

Dawson, L. M., Smith, K., Werdyani, S., Ndikumana, R., Penney, C., Wiede, L. L., Smith, K. L., Pater, J. A., MacMillan, A., Green, J., et al. (2019) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.1070 · Cited by 11

Impact of Chromatin Dynamics and DNA Repair on Genomic Stability and Treatment Resistance in Pediatric High-Grade Gliomas

Pinto, L., Baidarjad, H., Entz‐Werlé, N., & Dyck, E. V. (2021) · Cancers · doi:10.3390/cancers13225678 · Cited by 12

BCDX2–CX3 and DX2–CX3 complexes assemble and stabilize RAD51 filaments

Koo, C. W., Xiao, J., Coassolo, S., Liu, J., Yu, C., Azumaya, C. M., Gore, S. K., Cheung, T. K., Brillantes, B., Rose, C. M., et al. (2026) · Nature · doi:10.1038/s41586-026-10314-z · Cited by 12

Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA

Akita, M., Girvan, P., Špı́rek, M., Nováček, J., Rueda, D., Prokop, Z., & Krejčí, L. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae770 · Cited by 9

Inhibition ofDr‐dutgene causes DNA damage in planarian

Alam, M. S., Moriyama, H., & Matsumoto, M. (2018) · Molecular Reproduction and Development · doi:10.1002/mrd.22952 · Cited by 10

RAD51 paralogs promote genomic integrity and chemoresistance in cancer by facilitating homologous recombination

Harris, J. L., Rabellino, A., & Khanna, K. K. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.12.30 · Cited by 10

Remodeling and Control of Homologous Recombination by DNA Helicases and Translocases that Target Recombinases and Synapsis

Northall, S. J., Ivančić-Baće, I., Soultanas, P., & Bolt, E. L. (2016) · Genes · doi:10.3390/genes7080052 · Cited by 11

Loss of Rad51c accelerates tumourigenesis in sebaceous glands of Trp53‐mutant mice

Tumiati, M., Hemmes, A., Uusivirta, S., Koopal, S., Kankainen, M., Lehtonen, E., & Kuznetsov, S. G. (2014) · The Journal of Pathology · doi:10.1002/path.4455 · Cited by 9

A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair

Esposito, M. V., Minopoli, G., Esposito, L., D’Argenio, V., Maggio, F. D., Sasso, E., D’Aiuto, M., Zambrano, N., & Salvatore, F. (2019) · Cancers · doi:10.3390/cancers11101454 · Cited by 9

A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functions

França, M. M., Condezo, Y. B., Elzaïat, M., Felipe‐Medina, N., Sánchez-Sáez, F., Muñoz, S., Sainz-Urruela, R., Martín‐Hervás, M. D. R., García-Valiente, R., Sánchez‐Martín, M., et al. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01021-z · Cited by 10

Compound F779-0434 causes synthetic lethality in BRCA2-deficient cancer cells by disrupting RAD52–ssDNA association

Li, J., Yang, Q., Zhang, Y., Huang, K., Sun, R., & Zhao, Q. (2018) · RSC Advances · doi:10.1039/c8ra01919c · Cited by 9

TAZ maintains telomere length in TNBC cells by mediating Rad51C expression

Yang, L., Wang, B., Jiao, X., Zhou, C., Chen, S., Gao, X., Sun, W., Song, S., Li, J., Liu, J., et al. (2021) · Breast Cancer Research · doi:10.1186/s13058-021-01466-z · Cited by 9

Whole-genome and transcriptome analysis of advanced adrenocortical cancer highlights multiple alterations affecting epigenome and DNA repair pathways.Preprint

Lavoie, J., Csizmók, V., Williamson, L., Culibrk, L., Wang, G., Marra, M. A., Laskin, J. J., Jones, S. J. M., Renouf, D. J., & Kollmannsberger, C. (2022) · PubMed Central · doi:10.1101/mcs.a006148 · Cited by 11

Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and beyond

Rein, H. L., & Bernstein, K. A. (2023) · DNA repair · doi:10.1016/j.dnarep.2023.103563 · Cited by 10

RNA Expression of DNA Damage Response Genes in Muscle-Invasive Bladder Cancer: Influence on Outcome and Response to Adjuvant Cisplatin-Based Chemotherapy

Herrmann, J., Schmidt, H., Nitschke, K., Weis, C., Nuhn, P., von Hardenberg, J., Michel, M. S., Erben, P., & Worst, T. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084188 · Cited by 8

Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer

Tacar, S. Y., Bozgeyi̇k, E., Seber, S., Yetişyiğit, T., Tozkır, H., Avcı, O., & Arslan, A. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118334 · Cited by 7

Homologous Recombination-Mediated DNA Repair and Implications for Clinical Treatment of Repair Defective Cancers

Reilly, N. M., Yard, B. D., & Pittman, D. L. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9500-4_1 · Cited by 9

A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content

Sharaf, R., Jin, D. X., Grady, J. P., Napier, C. E., Ebot, E. M., Frampton, G. M., Albacker, L. A., Thomas, D. M., & Montesion, M. (2023) · npj Genomic Medicine · doi:10.1038/s41525-023-00369-6 · Cited by 6

Association between XRCC3 p.Thr241Met polymorphism and risk of glioma: A systematic review and meta-analysis

Tan, S. C., Low, T. Y., Hussain, H. M. J., Sharzehan, M. A. K., Sito, H., Kord‐Varkaneh, H., & Islam, M. A. (2022) · PLoS ONE · doi:10.1371/journal.pone.0276313 · Cited by 6

DNA Recombination Strategies During Antigenic Variation in the African Trypanosome

McCulloch, R., Morrison, L. J., & Hall, J. P. J. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch19 · Cited by 6

XRCC2 gene polymorphisms and its protein are associated with colorectal cancer susceptibility in Chinese Han population

Li, X., Luo, H., Huang, J., Zhang, J.-D., Yang, Z., & Sun, X. (2014) · Medical Oncology · doi:10.1007/s12032-014-0245-8 · Cited by 6

Rad51c- and Trp53-double-mutant mouse model reveals common features of homologous recombination-deficient breast cancers

Tumiati, M., Munne, P., Edgren, H., Eldfors, S., Hemmes, A., & Kuznetsov, S. G. (2016) · Oncogene · doi:10.1038/onc.2015.528 · Cited by 5

Germline mutations in RAD51C and RAD51D and hereditary predisposition to ovarian cancer

Soukupová, J., Lhotová, K., Janatová, M., Kleiblová, P., Vočka, M., Foretová, L., Zikán, M., & Kleibl, Z. (2021) · Klinicka onkologie · doi:10.48095/ccko202126 · Cited by 5

RADA is a main branch migration factor in plant mitochondrial recombination and its defect leads to mtDNA instability and cell cycle arrestPreprint

Chevigny, N., Weber‐Lotfi, F., Nadiras, C., Fertet, A., Ret, M. L., Bichara, M., Erhardt, M., Dietrich, A., Raynaud, C., & Gualberto, J. M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/856716 · Cited by 5

The RAD51D c.82G>A (p.Val28Met) variant disrupts normal splicing and is associated with hereditary ovarian cancer

Yang, C., Arnold, A. G., Catchings, A., Rai, V., Stadler, Z. K., & Zhang, L. (2021) · Breast Cancer Research and Treatment · doi:10.1007/s10549-020-06066-7 · Cited by 4

Homologous recombination deficiency in endometrial cancer: shedding light on recent clinical findings

Willman, G. H., Podder, V., Westin, S. N., Corr, B. R., Coleman, R. L., Pothuri, B., Moore, K. N., & Slomovitz, B. M. (2025) · International Journal of Gynecological Cancer · doi:10.1016/j.ijgc.2025.102859 · Cited by 3

SNV/indel hypermutator phenotype in biallelic RAD51C variant: Fanconi anemia

Zemet, R., Du, H., Gambin, T., Lupski, J. R., Liu, P., & Stankiewicz, P. (2023) · Human Genetics · doi:10.1007/s00439-023-02550-4 · Cited by 3

Association between rheumatoid arthritis and risk of radiotherapy toxicity: a systematic review

Liebenberg, N., McWilliam, A., Kerns, S. L., Marshall, D. C., & West, C. (2024) · BMJ Oncology · doi:10.1136/bmjonc-2024-000407 · Cited by 3

Retroperitoneal leiomyosarcoma in a female patient with a germline splicing variant RAD51D c.904-2A > T: a case report

Futagawa, M., Yamamoto, H., Kochi, M., Urakawa, Y., Sogawa, R., Kato, F., Okazawa‐Sakai, M., Ennishi, D., Shinozaki, K., Inoue, H., et al. (2021) · Hereditary Cancer in Clinical Practice · doi:10.1186/s13053-021-00205-x · Cited by 3

A cytological revisit on parthenogenetic Artemia and the deficiency of a meiosis-specific recombinase DMC1 in the possible transition from bisexuality to parthenogenesis

Lian-ying, X., Wu, W., Bi, N., Yan, Z.-J., Yang, F., Yang, W., & Yang, J. (2023) · Chromosoma · doi:10.1007/s00412-023-00790-x · Cited by 3

The effect of rhG-CSF on spleen transcriptome in mouse leukopenia model induced by cyclophosphamide

Guo, H., Sun, F., Huang, W., Liu, Z., Zhang, S., Zhou, Q., & Liang, C. (2014) · Immunopharmacology and Immunotoxicology · doi:10.3109/08923973.2013.869696 · Cited by 3

Effect of RAD51C expression on the chemosensitivity of Eμ-Myc p19Arf‑/‑ cells and its clinical significance in breast cancer

Liao, S., Liu, L., & Wang, Y. (2018) · Oncology Letters · doi:10.3892/ol.2018.8133 · Cited by 3

What About the Others? Clinical Management of Gynecologic Cancer Risk in Patients With Moderate-Risk Hereditary Cancer Genes (ATM, BRIP1, RAD51C, RAD51D, and PALB2)

Goldfeld, E., Kelly, B. E., & Ring, K. L. (2024) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000897 · Cited by 2

RAD52 and ERCC6L/PICH have a compensatory relationship for genome stability in mitosis

Osia, B., Merkell, A., Lopezcolorado, F. W., Ping, X., & Stark, J. M. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011479 · Cited by 2

GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1

Allam, H., Acklin, S., Sadhukhan, R., Patra, M., & Xia, F. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189956 · Cited by 3

Medulloblastoma and the DNA Damage Response

McSwain, L., Parwani, K. K., Shahab, S., Hambardzumyan, D., MacDonald, T. J., Spangle, J. M., & Kenney, A. M. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.903830 · Cited by 2

Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability

Simo‐Cheyou, E. R., Boni, J., Boulais, J., Carpio, E. P., Malina, A., Sherill-Rofe, D., Luo, V. M., Gonçalves, C., Bagci, H., Maters, A., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010495 · Cited by 2

Host repair polymorphisms and H. pylori genes in gastric disease outcomes: Who are the guardian and villains?

Barboza, M. M. D. O., da Costa, R. F., Gomes, J. P., Burbano, R. M. R., Silva, P. G. D. B., & Rabenhorst, S. H. B. (2024) · Gene · doi:10.1016/j.gene.2024.148977 · Cited by 2

The Impact of Uncommon HRR Alterations as Predictors of Efficacy of PARP Inhibitors in Metastatic Castration-Resistant Prostate Cancer: A Meta-Analysis of Randomized Controlled Trials

Pinterpe, G., Migliaccio, F., Ciccarese, C., Pedone, R. R., Belletto, R., Russo, P., Totaro, A., Tagliaferri, L., Sighinolfi, M. C., Formisano, L., et al. (2025) · Targeted Oncology · doi:10.1007/s11523-025-01141-9 · Cited by 3

Polymorphic Variants in 5′-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study

Hamad, M. A., Kussaibi, H., Alkharsah, K. R., Alsayyah, A., Shawarby, M. E., Tamimi, D. A., Alomari, M., Bakshi, H. A., Tambuwala, M. M., & Zoubi, M. S. A. (2021) · Applied immunohistochemistry & molecular morphology · doi:10.1097/pai.0000000000000900 · Cited by 2

Hot on RAD51C: structure and functions of RAD51C‐XRCC3

Szakál, B., & Branzei, D. (2023) · Molecular Oncology · doi:10.1002/1878-0261.13518 · Cited by 2

The RAD51 paralogue HvXRCC2 affects meiosis and recombination in barley

Colas, I., MacAulay, M. A., Arrieta, M., Schreiber, M., Orr, J., Sandhu, A., Augustine, A., Targońska-Karasek, M., Armstrong, S. J., Waugh, R., et al. (2025) · Journal of Experimental Botany · doi:10.1093/jxb/eraf489 · Cited by 1

Particulate Hexavalent Chromium Inhibits RAD51 Paralogs Necessary for RAD51 Filament Formation and Stabilization During Homologous Recombination Repair

Williams, A., Meaza, I., Lu, H., Wise, J. T. F., Diven, S. S., Toyoda, J. H., Kouokam, J. C., & Wise, J. P. (2026) · Occupational Health · doi:10.3390/occuphealth1010013 · Cited by 1

Single-Molecule Tethered Particle Motion Studies on the DNA Recombinase Filament Assembly and Disassembly

Lu, C., Lan, W.-H., & Li, H. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1290-3_8 · Cited by 1

Molecular genetic markers of ovarian cancer tumor cells and their microenvironment, study methods, and clinical value: A review

Kalfa, M. A., Golovkin, I. O., Lazarev, A. E., Golubinskaya, E. P., Gritskevich, O. Y., & Zyablitskaya, E. Y. (2023) · Journal of Modern Oncology · doi:10.26442/18151434.2023.3.202422 · Cited by 1

Epidemiology and Genetic Susceptibility of Breast and Ovarian Cancer in Sardinian Population

Palomba, G., Palmieri, G., Cossu, A., Paliogiannis, P., & Sini, M. C. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.90517 · Cited by 2

Next generation sequencing of cervical high grade dysplasia and invasive squamous cell carcinoma: A case study

Vormittag-Nocito, E. R., Groth, J., & Mohapatra, G. (2020) · Pathology - Research and Practice · doi:10.1016/j.prp.2020.152863 · Cited by 1

C1orf112 is a novel regulator of interstrand crosslink that decreases FIGNL1-RAD51 interactionPreprint

Carpio, E. P., Dessapt, J., Villot, R., Sacre, L., Malina, A., Boulais, J., Lavoie, É. G., Luo, V. M., Lazaratos, A.-M., Côté, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.06.511186 · Cited by 2

The RAD51 paralogue HvXRCC2 regulates meiosis and recombination in barleyPreprint

Colas, I., MacAulay, M. A., Arrieta, M., Schreiber, M., Orr, J., Sandhu, A., Augustine, A., Targońska-Karasek, M., Armstrong, S. J., Waugh, R., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.05.561044 · Cited by 1

Inactivation of a protein hydroxylase complex impairs replication fork restart in cancer and neurodevelopmental disordersPreprint

Kennedy, T. J., Fletcher, S. C., Boora, U., Fraser-Williams, E., Kaur, A., Hughes, G. W., Hendrix, E., Morris, J. R., Smerdon, S. J., & Coleman, M. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.22.689938 · Cited by 1

Distinct complexes of RAD51 paralogs participate in different fork protection pathwaysPreprint

Bhattacharya, D., Dwivedi, H. K., Sahoo, S., Kadupatil, S., & Nagaraju, G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.29.721569 · Cited by 1

RAD51C IS A TUMOR SUPPRESSOR IN MAMMARY AND SEBACEOUS GLANDS

Tumiati, M. (2015) · Työväentutkimus Vuosikirja

Influência do gene PTEN na expressão de RAD51 e suas parálogas, RAD51C e RAD51B, em linhagens de glioblastoma multiforme tratadas com etoposídeo

Oliveira, A. C. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2016.tde-27072016-143803

RAD51 paralogs regulate double strand break repair pathway choice by limiting Ku complex retentionPreprint

Mejías-Navarro, F., Gómez-Cabello, D., & Huertas, P. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/282855

Identifizierung von Patientinnen und Patienten mit der hereditären Form des Mamma- und Ovarialkarzinoms mittels Next-Generation-Sequencing-(NGS)-Technologie

Smogavec, M. (2019) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7487

XAB2 prevents abortive recombinational repair of replication-associated DNA double-strand breaks and its loss is synthetic lethal with RAD52 inhibitionPreprint

Sharma, A. B., Erasimus, H., Pinto, L., Caron, M., Neumann, K., Nazarov, P. V., Klink, B., Fritah, S., Herold-Mende, C. C., Niclou, S. P., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.10.035410

RAD51C and RAD51D in the hereditary breast and ovarian cancer syndrome

Bermúdez, A. I. S., Meseguer, M. A. D. S., Guardiola, V. C., Espejo, F. R., & Velasco, J. A. N. (2020) · Revista de Medicina de Laboratorio · doi:10.20960/revmedlab.00024

Natural and Synthetic Strategies for DNA Maintenance and Recording

Gharaei, N. (2019) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

XRCC2 gene polymorphisms and its protein are associated with colorectal cancer susceptibility in Chinese Han population

LiHua, X.-B., & Huang, L. (2014)

Faculty Opinions recommendation of RAD51C/XRCC3 facilitates mitochondrial DNA replication and maintains integrity of the mitochondrial genome.

Prakash, A., & Sharma, N. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732142212.793540877

Faculty Opinions recommendation of Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication.

Kanaar, R. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.726379828.793550437

Jinekolojik Onkoloji Pratiğimizde Risk Azaltıcı Cerrahi Yönetimi Gerektiren Genetik Değişiklikler

Kazancı, F., & Şahin, F. İ. (2022) · Arşiv Kaynak Tarama Dergisi · doi:10.17827/aktd.1059207

Particulate hexavalent chromium inhibits homologous recombination repair by targeting RAD51 paralogs in human lung fibroblasts.

Williams, A. (2022) · doi:10.18297/etd/3873

Data from Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Pellegrino, B., Herencia-Ropero, A., Llop‐Guevara, A., Pedretti, F., Moles‐Fernández, A., Viaplana, C., Villacampa, G. J., Guzmán, M., Rodríguez, O., Grueso, J., et al. (2023) · doi:10.1158/0008-5472.c.6513876.v1

Data from Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C

Hu, C., Nagaraj, A. B., Shimelis, H., Montalban, G., Lee, K. Y., Huang, H., Lumby, C. A., Na, J., Susswein, L. R., Roberts, M. E., et al. (2023) · doi:10.1158/0008-5472.c.6769332

Data from Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes

Pikkusaari, S., Tumiati, M., Virtanen, A., Oikkonen, J., Li, Y., Pérez‐Villatoro, F., Muranen, T., Salko, M., Huhtinen, K., Kanerva, A., et al. (2023) · doi:10.1158/1078-0432.c.6533165.v2

Genetic behind breast cancer: Germline and somatic factors

Sharma, R., Sharma, R. K., Khodke, P., Tiwari, J. K., Garg, V. K., Okpala, C. O. R., Buttar, H. S., Thakur, S., Goel, N., & Kashyap, D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24838-2.00005-7

Isoform switching as a key mechanism in chemotherapy resistance in triple-negative breast cancerPreprint

Nowis, K., Sasiadek, M. M., Martynowski, D., Kujawa, D., Łaczmańska, I., Karpiński, P., Ekiert, M., Iwaneczko, E., Szynglarewicz, B., Kasprzak, P., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7041176/v1

Additional file 1 of TAZ maintains telomere length in TNBC cells by mediating Rad51C expression

Yang, L., Wang, B., Jiao, X., Zhou, C., Chen, S., Gao, X., Sun, W., Song, S., Li, J., Liu, J., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16575473

Dss1 facilitates Rad51 recruitment downstream of BRCA2/Brh2 in response to DNA damage

Juhl, L., Busch, L., Bagge, J., Xu, R., Kojić, M., Milisavljević, M., Oestergaard, V. H., Holloman, W. K., & Lisby, M. (2026) · DNA repair · doi:10.1016/j.dnarep.2026.103923

The power and limits of predicting inter-protein exon-exon interactions using protein 3D structures

Liebold, J., Moral‐Morales, A. D., Manalastas-Cantos, K., Tsoy, O. V., Kurtz, S., Baumbach, J., & Newaz, K. (2026) · Bioinformatics Advances · doi:10.1093/bioadv/vbag032

SFPQ Promotes Homologous Recombination via mRNA Stabilization of RAD51 and Its Paralogs

Gotthold, S., Hansen, K. R., Brown, A. N., Chowdhury, S. P., Joyce, C. M., Vinish, V., Rodriguez, S. I., Jain, S., Ghasemi, H. I., Yoon, A. C., et al. (2026) · Journal of Molecular Biology · doi:10.1016/j.jmb.2026.169677

Homologous recombination in Bacteriophages, less fidelity for more exchanges

Hutinet, G. (2014) · theses.fr (ABES) · doi:10.70675/3a79d928z8c92z465azbedbz536a1db400b9

RAD51 Protects Against RAD52-Dependent Non-Conservative Double-Strand Break Repair Processes, by Impeding the Annealing Step

So, A. (2018) · theses.fr (ABES) · doi:10.70675/2db5ae5fzd2c0z4df3zb852zec2a10a44314

Caractérisation des fonctions de TRCF et de RADA dans l'expression et la maintenance des génomes des organelles chez Arabidopsis thaliana

Chevigny, N. (2019) · theses.fr (ABES) · doi:10.70675/8b9a6afdz0f25z40fbz9e71z326e28292711

Etude et développement de petites molécules inhibitrices de la réparation de l’ADN par recombinaison homologue

Demeyer, A. (2020) · theses.fr (ABES) · doi:10.70675/c0fc55bfzb8ddz4c6bz97a4z3e2c94292bd9

RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2Preprint

Thrasher, J. G., Fagunloye, A. A., Justiniano, F. S., Bernstein, K. A., & Jensen, R. B. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.10.617680 · Cited by 5

BCDX2–CX3 and DX2–CX3 complexes assemble and stabilize RAD51 filaments

Koo, C. W., Xiao, J., Coassolo, S., Liu, J., Yu, C., Azumaya, C. M., Gore, S. K., Cheung, T. K., Brillantes, B., Rose, C. M., et al. (2026) · Nature · doi:10.1038/s41586-026-10314-z · Cited by 12

Structural insights into BCDX2 complex function in homologous recombination

Rawal, Y., Jia, L., Meir, A., Zhou, S., Kaur, H., Ruben, E. A., Kwon, Y., Bernstein, K. A., Jasin, M., Taylor, A. B., et al. (2023) · Nature · doi:10.1038/s41586-023-06219-w · Cited by 57

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

Liu, N. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.4.1009 · Cited by 129

Structure-function studies of the tumour suppressor complex RAD51B-RAD51C-RAD51D-XRCC2

Greenhough, L. (2023) · doi:10.25560/126500