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Peroxisome Proliferator-Activated Receptor γ and C/EBPα Synergistically Activate Key Metabolic Adipocyte Genes by Assisted Loading
Open accessAbstract
Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα) are key activators of adipogenesis. They mutually induce the expression of each other and have been reported to cooperate in activation of a few adipocyte genes. Recently, genome-wide profiling revealed a high degree of overlap between PPARγ and C/EBPα binding in adipocytes, suggesting that cooperativeness could be mediated through common binding sites. To directly investigate the interplay between PPARγ and C/EBPα at shared binding sites, we established a fibroblastic model system in which PPARγ and C/EBPα can be independently expressed. Using RNA sequencing, we demonstrate that coexpression of PPARγ and C/EBPα leads to synergistic activation of many key metabolic adipocyte genes. This is associated with extensive C/EBPα-mediated reprogramming of PPARγ binding and vice versa in the vicinity of these genes, as determined by chromatin immunoprecipitation combined with deep sequencing. Our results indicate that this is at least partly mediated by assisted loading involving chromatin remodeling directed by the leading factor. In conclusion, we report a novel mechanism by which the key adipogenic transcription factors, PPARγ and C/EBPα, cooperate in activation of the adipocyte gene program.
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“Assisted loading has been described in various systems30–37.”
From Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading (2017) · cites this paper as [33]
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Cites
BEDTools: a flexible suite of utilities for comparing genomic features
Quinlan, A. R., & Hall, I. M. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq033 · Cited by 27,437
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.
Langmead, B., Trapnell, C., Pop, M., & Salzberg, S. L. (2009) · Genome Biology · doi:10.1186/gb-2009-10-3-r25 · Cited by 21,849
Differential expression analysis for sequence count data
Anders, S., & Huber, W. (2010) · Genome Biology · doi:10.1186/gb-2010-11-10-r106 · Cited by 15,581
Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y. C., Laslo, P., Cheng, J. X., Murre, C., Singh, H., & Glass, C. K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.05.004 · Cited by 13,382
The Human Genome Browser at UCSC
Kent, W. J., Sugnet, C. W., Furey, T. S., Roskin, K. M., Pringle, T. H., Zahler, A. M., & Haussler, A. D. (2002) · Genome Research · doi:10.1101/gr.229102 · Cited by 10,400
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
Tontonoz, P., Hu, E., & Spiegelman, B. M. (1994) · Cell · doi:10.1016/0092-8674(94)90006-x · Cited by 3,564
Adipocyte differentiation from the inside out
Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607
PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro
Rosen, E. D., Sarraf, P., Troy, A. E., Bradwin, G., Moore, K. J., Milstone, D. S., Spiegelman, B. M., & Mortensen, R. M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80211-7 · Cited by 2,081
PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development
Barak, Y., Nelson, M. C., Ong, E. S., Jones, Y., Ruiz‐Lozano, P., Chien, K. R., Koder, A., & Evans, R. M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80209-9 · Cited by 1,983
Transcriptional control of adipocyte formation
Farmer, S. R. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.07.001 · Cited by 1,836
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Research works printed but not linked: 2
- Herrera R, 1989, Mol. Cell. Biol., 9, 5331
- Park EA, 1990, Mol. Cell. Biol., 10, 6264
Cited by
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Items 101–200 of 272
Oh, Y., Ahn, C., & Je, J. (2020) · Food Research International · doi:10.1016/j.foodres.2020.109603 · Cited by 22
Yasmin, T., Menon, S. N., Pandey, A., Siddiqua, S., Kuddus, S. A., Alam, M. A., Khan, F., Hoque, N., Alam, M. A., Subhan, N., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-08450-z · Cited by 21
Bathina, S., & Armamento‐Villareal, R. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1168687 · Cited by 27
Xu, H., Wang, F., Wang, J., Xu, J., Wang, Y., & Xue, C. (2015) · Food & Function · doi:10.1039/c5fo00273g · Cited by 22
Bitirim, C. V., Aksoy, Z. B., & Akçalı, K. C. (2021) · PeerJ · doi:10.7717/peerj.12071 · Cited by 21
Goldberg, D. T., Charni‐Natan, M., Buchshtab, N., Bar‐Shimon, M., & Goldstein, I. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac358 · Cited by 21
The emerging roles of PHOSPHO1 and its regulated phospholipid homeostasis in metabolic disorders
Liu, Y., Wu, Y., & Jiang, M. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.935195 · Cited by 20
Örd, T., Örd, D., & Örd, T. (2018) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2018.01.014 · Cited by 20
Andrade, M. L., Gilio, G. R., Perandini, L. A., Peixoto, Á. S., Moreno, M. F., Castro, É., Oliveira, T. E., Vieira, T. S., Ortiz‐Silva, M., Thomazelli, C. A., et al. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2021.158967 · Cited by 22
Notch1 haploinsufficiency in mice accelerates adipogenesis
Yamaguchi, K., Hayashi, M., Uchida, Y., Cheng, X. W., Nakayama, T., Matsushita, T., Murohara, T., & Takeshita, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-96017-z · Cited by 19
Lee, D., Kim, J. Y., Qi, Y., Park, S., Lee, H. L., Yamabe, N., Kim, H., Jang, D. S., & Kang, K. S. (2021) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2021.128326 · Cited by 19
Crobeddu, B., Jutras-Carignan, A., Kolasa, É., Mounier, C., Robaire, B., & Plante, I. (2022) · Toxicological Sciences · doi:10.1093/toxsci/kfac076 · Cited by 23
Hong, K. H., Um, M. Y., Ahn, J., & Ha, T. Y. (2023) · Nutrients · doi:10.3390/nu15153457 · Cited by 20
Wagh, K., Stavreva, D. A., Jensen, R. A., Paakinaho, V., Fettweis, G., Schiltz, R. L., Wüstner, D., Mandrup, S., Presman, D. M., Upadhyaya, A., et al. (2023) · UEF eRepo (University of Eastern Finland) · doi:10.5281/zenodo.7558777 · Cited by 19
Self-citationZhao, J., Qian, H., An, Y., Chu, L., Tan, D., Qin, C., Sun, Q., Wang, Y., & Qi, W. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107765 · Cited by 19
Zarkesh, M., Tabaei, K., Akbarzadeh, M., Daneshafrooz, A., & Zadeh–Vakili, A. (2022) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.1186/s40101-022-00286-0 · Cited by 21
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Zhang, G., Zhou, Y., Su, M., Yang, X., & Zeng, B. (2020) · BioFactors · doi:10.1002/biof.1670 · Cited by 17
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Chung, S., Kim, Y. J., Yang, S. J., Lee, Y., & Lee, M. (2016) · PPAR Research · doi:10.1155/2016/4794576 · Cited by 19
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Kim, J., Na, H., Kim, J., & Nam, J. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-0536-4 · Cited by 17
Bae, S. M., Fan, M., Choi, Y., Tang, Y., Jeong, G., Myung, K., Kim, B., & Kim, E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228537 · Cited by 17
Jiang, M., Li, L., Huang, W.-F., Su, J. J., Li, Y., Qu, X., & Fan, L. (2021) · Journal of Natural Medicines · doi:10.1007/s11418-021-01536-8 · Cited by 17
Hoi, J. K., Lieder, B., Liebisch, B., Czech, C., Hans, J., Ley, J. P., & Somoza, V. (2020) · ACS Omega · doi:10.1021/acsomega.0c05083 · Cited by 16
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Lee, J. H., Lee, S., Park, J. Y., Park, I.-H., Kang, K. S., & Shin, M. (2023) · Processes · doi:10.3390/pr11040977 · Cited by 16
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Cahyadi, D. D., Warita, T., Irie, N., Mizoguchi, K., Tashiro, J., Hosaka, Y. Z., & Warita, K. (2023) · Adipocyte · doi:10.1080/21623945.2023.2235081 · Cited by 16
Yoon, Y., Chung, K., Lee, S., Heo, S.-W., Kim, Y.-R., Lee, J. K., Kim, H.-J., Park, S., Shin, Y., & Lee, K. (2024) · Food & Function · doi:10.1039/d4fo00759j · Cited by 16
Ploner, C., Rauchenwald, T., Connolly, C. E., Jöhrer, K., Rainer, J., Seifarth, C., Hermann, M., Nagl, M., Lobenwein, S., Wilflingseder, D., et al. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02336-3 · Cited by 17
D-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats
Lee, G., Peng, C. Y., Lee, H., Park, S., Hoang, T., Kim, J., Sa, S., Kim, G., Han, J.-S., & Chae, H. (2021) · Food & Nutrition Research · doi:10.29219/fnr.v65.7803 · Cited by 16
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Shukla, V., Cetnarowska, A., Hyldahl, M., & Mandrup, S. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.05.011 · Cited by 15
Self-citationTian, Y., Hu, S., Xu, H., Wang, J., Xue, C., & Wang, Y. (2016) · Food Science and Biotechnology · doi:10.1007/s10068-016-0267-4 · Cited by 16
Berrichi, M., Hichami, A., Addou-Klouche, L., Khan, A. S., & Khan, N. A. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061956 · Cited by 16
Kuddus, S. A., Bhuiyan, M. I., Subhan, N., Shohag, M. H., Rahman, A. S. M. Z., Hossain, M., Alam, M. A., & Khan, F. (2020) · Clinical Phytoscience · doi:10.1186/s40816-020-00213-9 · Cited by 15
Kornicka‐Garbowska, K., Bourebaba, L., Röcken, M., & Marycz, K. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-021-00772-5 · Cited by 15
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Gao, T., Lai, M., Zhu, X., Ren, S., Yin, Y., Wang, Z., Liu, Z., Zuo, Z., Hou, Y., Pi, J., et al. (2021) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115393 · Cited by 14
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Bianconi, E., Tassinari, R., Alessandrini, A., Ragazzini, G., Cavallini, C., Abruzzo, P. M., Petrocelli, G., Pampanella, L., Casadei, R., Maioli, M., et al. (2022) · Cells · doi:10.3390/cells11101629 · Cited by 14
Zhang, H., & Guan, W. (2019) · Animal Science Journal · doi:10.1111/asj.13170 · Cited by 13
Horváth, A., Dániel, B., Széles, L., Cuaranta‐Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simándi, Z., Póliska, S., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz118 · Cited by 13
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Gerstner, M., Heller, V., Fechner, J., Hermann, B., Wang, L., & Lausen, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-57310-9 · Cited by 12
Yılmaz, B., Erdogan, C. S., Sandal, S., Keleştimur, F., & Carpenter, D. O. (2024) · Neuroendocrinology · doi:10.1159/000542901 · Cited by 13
Huang, C.-J., Choo, K., & Chen, C. (2022) · Poultry Science · doi:10.1016/j.psj.2022.101950 · Cited by 13
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Pamplona, J. H., Zoehler, B., Shigunov, P., Barisón, M. J., Severo, V. R., Erich, N. M., Ribeiro, A. L., Horinouchi, C. D. D. S., Suzukawa, A. A., Robert, A. W., et al. (2022) · Life · doi:10.3390/life13010108 · Cited by 14
Hwang, J. M., Lee, M., Lee, J., & Lee, J. H. (2021) · Applied Sciences · doi:10.3390/app11167679 · Cited by 12
Sharifi‐Zahabi, E., Hajizadeh‐Sharafabad, F., Nachvak, S. M., Mirzaeian, S., Darbandi, S., & Shidfar, F. (2023) · Phytotherapy Research · doi:10.1002/ptr.7916 · Cited by 11
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Popa, A. D., Niță, O., Caba, L., Gherasim, A., Graur, M., Mihalache, L., & Arhire, L. I. (2023) · Metabolites · doi:10.3390/metabo14010004 · Cited by 15
Castilla‐Casadiego, D. A., Morton, L. D., Loh, D. H., Pineda‐Hernandez, A., Chavda, A. P., Garcia, F., & Rosales, A. M. (2024) · Macromolecular Bioscience · doi:10.1002/mabi.202400111 · Cited by 11
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Zhang, L., Zhu, Y.-N., Gao, Y., Liu, S., Zhai, B., Li, C., Liu, H., Chen, J., Yuan, B., Dai, L., et al. (2014) · Cellular Physiology and Biochemistry · doi:10.1159/000366333 · Cited by 11
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Egorov, A. D., Penkov, D., & Va, T. (2015) · Diabetes Mellitus · doi:10.14341/dm2015212-19 · Cited by 11
Kakhki, B. R., Moradi, E. V., Vossoughinia, S., Yazdanpanah, Z., Jalali, J., & Rahbardar, M. G. (2025) · Fitoterapia · doi:10.1016/j.fitote.2025.106795 · Cited by 10
Wang, Y., Chen, R., Li, J., Zeng, G., Yuan, J.-T., Su, J., Wu, C., Lu, Z., Zhang, F., & Ding, W. (2022) · Antioxidants · doi:10.3390/antiox11061093 · Cited by 10
Li, Y., Baumert, B. O., Costello, E. J., Chen, J. C., Rock, S., Stratakis, N., Goodrich, J. A., Zhao, Y., Eckel, S. P., Walker, D. I., et al. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117832 · Cited by 10
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Oh, K.-I., Lim, E., Uprety, L. P., Jeong, J., Jeong, H., Park, E., & Jeong, S. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116762 · Cited by 10
Kim, I.-K., Song, B., Lim, S., Kim, S. W., & Lee, S. (2023) · Biology · doi:10.3390/biology12040498 · Cited by 12
Dubois‐Chevalier, J., Staels, B., Lefèbvre, P., & Eeckhoute, J. (2015) · Nucleus · doi:10.1080/19491034.2015.1004258 · Cited by 10
Go, G., Sung, J., Jee, S.-C., Kim, M., Jang, W.-H., Kang, K., Kim, D.-Y., Lee, S., & Shin, H.-S. (2017) · Food Science and Biotechnology · doi:10.1007/s10068-017-0026-1 · Cited by 10
Boughanem, H., Cabrera-Mulero, A., Hernández‐Alonso, P., Bandera-Merchán, B., Tinahones, A., Tinahones, F. J., Morcillo, S., & Macías‐González, M. (2019) · Cancers · doi:10.3390/cancers11111629 · Cited by 10
Izumi, M., Yoshida, T., Nakamura, T., & Wakamori, M. (2020) · Nutrients · doi:10.3390/nu12020309 · Cited by 10
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice
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Diao, B., Fan, Z., Zhou, B., & Zhan, H. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.151012 · Cited by 9
Preciado-Ortiz, M. E., Gembe‐Olivarez, G., Martínez‐López, E., & Rivera-Valdes, J. J. (2025) · Molecules · doi:10.3390/molecules30142933 · Cited by 11
A Novel Dnmt3a1 Transcript Inhibits Adipogenesis
Abdalla, B. A., Li, Z., Ouyang, H., Jebessa, E., Sun, T., Yu, J., Cai, B., Chen, B., Nie, Q., & Zhang, X. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01270 · Cited by 9
Inokawa, A., Inuzuka, T., Takahara, T., Shibata, H., & Maki, M. (2015) · Bioscience Reports · doi:10.1042/bsr20150215 · Cited by 9
Zhou, Y., Kim, J. T., Qiu, S., Lee, S. B., Park, H. J., Soon, M. J., & Lee, H. J. (2022) · Food Science and Biotechnology · doi:10.1007/s10068-022-01130-y · Cited by 8
Abebe, B. K., Wang, H., Li, A., & Zan, L. (2023) · Journal of Animal Breeding and Genetics · doi:10.1111/jbg.12841 · Cited by 8
Dowker-Key, P. D., Kumar, J. P., Gill, N. B., Hubbard, K. N., Elshaarrawi, A., Alfatlawy, N. D., & Bettaieb, A. (2024) · Genes · doi:10.3390/genes15081017 · Cited by 13
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Jee, W., Cho, H.-S., Kim, S. W., Bae, H., Chung, W., Cho, J., Kim, H., Song, M., & Jang, H.-J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168572 · Cited by 9
Colom‐Pellicer, M., Rodríguez, R. M., Navarro‐Masip, È., Bravo, F. I., Mulero, M., Arola, L., & Aragonès, G. (2022) · International Journal of Obesity · doi:10.1038/s41366-022-01132-0 · Cited by 9
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Dhinekaran, A., Lakshmi, M. B. S., Graceline, H., Dey, A. K., Adhikari, S., Ramalingam, S., Ramachandran, I., Bişgin, A., Boğa, İ., Pathak, S., et al. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18800-8.00007-1 · Cited by 8
Yu, X., Liu, C., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y., et al. (2025) · Journal of Virology · doi:10.1128/jvi.01509-25 · Cited by 7
Kubota, Y., Nagano, H., Kosaka, K., Ogata, H., Nakayama, A., Yokoyama, M., Murata, K., Akita, S., Kuriyama, M., Furuyama, N., et al. (2021) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00387.2020 · Cited by 7
Park, S., Jeong, H. Y., Choi, P. G., Kim, M. J., Seo, H., Hahm, J., Ahn, J., & Jung, C. H. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.103028 · Cited by 7
Sekar, M., & Thirumurugan, K. (2024) · Molecular Biotechnology · doi:10.1007/s12033-023-01020-6 · Cited by 7
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Chen, J., Pan, Y., Lu, Y., Xue, F., Ma, T., Chen, X., Wang, Y., Fang, X., Zhang, C., & Song, C. (2024) · Genes · doi:10.3390/genes15070875 · Cited by 7
Goldberg, D. T., Buchshtab, N., Charni‐Natan, M., & Goldstein, I. (2024) · Liver International · doi:10.1111/liv.16077 · Cited by 7
Moustafa, E. M., Rashed, E. R., & Rashed, R. R. (2021) · Natural Product Communications · doi:10.1177/1934578x211001267 · Cited by 8
Caveolin‐2 in association with nuclear lamina controls adipocyte hypertrophy
Choi, M., Kwon, H., & Pak, Y. (2023) · The FASEB Journal · doi:10.1096/fj.202201028rr · Cited by 7
Preciado-Ortiz, M. E., Martínez‐López, E., Rodriguez‐Echevarría, R., Pérez-Robles, M., Gembe‐Olivarez, G., & Rivera-Valdes, J. J. (2023) · Biomedical Reports · doi:10.3892/br.2023.1687 · Cited by 9
Gina, N. N. T., Kuo, J.-L., Wu, M., & Chuang, S. (2023) · Nutrition Research · doi:10.1016/j.nutres.2023.12.011 · Cited by 7
Optimization of adipogenic differentiation conditions for canine adipose-derived stem cells
Kim, J., Park, E., Kim, S. M., & Lee, H. (2021) · Journal of Veterinary Science · doi:10.4142/jvs.2021.22.e53 · Cited by 7
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Lin, T., Zhang, Y., Zhang, T., Steckler, R. A., & Yang, X. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101264 · Cited by 7
Modulating the Genomic Programming of AdipocytesPreprint
Loft, A., Schmidt, S. F., & Mandrup, S. (2015) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2015.80.027516 · Cited by 7
Self-citationLee, J., Kim, B.-R., Park, K.-H., Kim, E., Jeong, J.-W., Kim, J. J., Suh, S., & Seo, J. B. (2025) · Animal Cells and Systems · doi:10.1080/19768354.2025.2536022 · Cited by 6
Perry, B. W., McDonald, A. L., Trojahn, S., Saxton, M. W., Vincent, E. P., Lowry, C., Hutzenbiler, B. D. E., Cornejo, O. E., Robbins, C. T., Jansen, H. T., et al. (2023) · Physiological Genomics · doi:10.1152/physiolgenomics.00030.2023 · Cited by 6
Barbalho, S. M., Goulart, R. D. Á., Minniti, G., Bechara, M. D., de Castro, M. V. M., Dias, J. A., & Laurindo, L. F. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02834-6 · Cited by 6
Munkong, N., Jantarach, N., Yoysungnoen, B., Lonan, P., Makjaroen, J., Pearngam, P., Kumpunya, S., Ruxsanawet, K., Nanthawong, S., Somparn, P., et al. (2024) · Antioxidants · doi:10.3390/antiox13121485 · Cited by 6
Nagy, G., Dániel, B., Cuaranta‐Monroy, I., & Nagy, L. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00547-19 · Cited by 6
Kim, H., Ahn, Y. M., Lee, S. M., Seo, C., Park, S., Bang, O., & Jung, J. (2022) · Nutrients · doi:10.3390/nu14142929 · Cited by 6
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Metadata
- Authors
- Madsen, M. S., Siersbæk, R., Boergesen, M., Nielsen, R., & Mandrup, S.
- Affiliations
- University of Southern Denmark (DK)
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 2014-03-01
- Volume
- 34
- Issue
- 6
- Pages
- 939-954
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- PMC
- PMC3958030
- OpenAlex
- W2170714239
- Cited by
- 272
- References
- 69
- Citations by year
- 2026: 16 · 2025: 24 · 2024: 38 · 2023: 39 · 2022: 34 · 2021: 28 · 2020: 19 · 2019: 15 · 2018: 14 · 2017: 15 · 2016: 9 · 2015: 14 · 2014: 7
- FWCI
- 4.48
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Molecular and Cellular Biology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (publishedVersion)
- Funders
- Lundbeckfonden (R118-2012-11639)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Keywords
- PPARγ, C/EBPα, transcriptional cooperativity, chromatin remodeling, adipocyte gene expression, adipogenesis, transcription factor binding sites, fibroblasts, metabolic genes, transcriptional regulation
- MeSH terms
- Animals, Binding Sites, Cell Line, Chromatin, Fibroblasts, Protein Binding, 3T3 Cells, Adipocytes, CCAAT-Enhancer-Binding Proteins, PPAR gamma, Mice
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