The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Increased Activity of Hypoxia-Inducible Factor 1 Is Associated with Early Embryonic Lethality in Commd1 Null Mice
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A complete loss of components of the endosomal recycling machinery is lethal in mice.
“This combined with the notion that a complete loss of components of the endosomal recycling machinery is lethal in mice 12,13,37 indicated that impairment of this pathway is very harmful.”
From A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor (2020) · cites this paper as [37]
The Results report that complete loss of COMMD1 causes embryonic lethality in mice, with null embryos dying around 9.5–10.5 days of gestation. The paper does not identify COMMD1 as a component of the endosomal recycling machinery, so it supports the lethality example but not that characterization. (LLM, conf=0.84)
Experimental — accuracy not yet measuredWhen COMMD9 is knocked out, CCDC22 cannot bind COMMD5 or COMMD10 but retains its ability to bind COMMD6, COMMD4, and COMMD8.
“We previously reported41 that when COMMD9 is knocked out, CCDC22 cannot bind COMMD5 or COMMD10 but retains its ability to bind to COMMD6, COMMD4, COMMD8.”
From Structural organization of the retriever–CCC endosomal recycling complex (2024) · cites this paper as [41]
The Abstract and Results describe a Commd1 knockout and its effects on early mouse embryos, not a COMMD9 knockout. Searches for CCDC22 binding and the named COMMD proteins found no passage in our copy addressing the claimed binding pattern. (LLM, conf=0.76)
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Citations
Cites
Cellular and developmental control of O 2 homeostasis by hypoxia-inducible factor 1α
Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., Gassmann, M., Gearhart, J. D., Lawler, A. M., Yu, A. Y., et al. (1998) · Genes & Development · doi:10.1101/gad.12.2.149 · Cited by 2,476
Regulation of Mammalian O 2 Homeostasis by Hypoxia-Inducible Factor 1
Semenza, G. L. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.551 · Cited by 1,914 · cited 1×
“5-dpc Commd1 / embryos have previously been shown to be induced by the transcription factor HIF-1 (1, 16, 25, 35, 42) (Table 2).”
BackgroundHIF-1-mediated activation of transferrin receptor gene transcription by iron chelation
Bianchi, L., Tacchini, L., & Cairo, G. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.21.4223 · Cited by 189
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Cited by
Sorted by citations
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
Bartuzi, P., Billadeau, D. D., Favier, R., Rong, S., Dekker, D., Fedoseienko, A., Fieten, H., Wijers, M., Levels, J. H., Huijkman, N., et al. (2016) · Nature Communications · doi:10.1038/ncomms10961 · Cited by 205
Endosomal retrieval of cargo: Retromer is not alone
McNally, K. E., & Cullen, P. J. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.06.005 · Cited by 169
Fedoseienko, A., Wijers, M., Wolters, J. C., Dekker, D., Smit, M., Huijkman, N., Kloosterhuis, N., Klug, H., Schepers, A., Willems van Dijk, K., et al. (2018) · Circulation Research · doi:10.1161/circresaha.117.312004 · Cited by 126
Structural organization of the retriever–CCC endosomal recycling complex
Boesch, D. J., Singla, A., Han, Y., Kramer, D. A., Liu, Q., Suzuki, K., Juneja, P., Zhao, X., Long, X., Medlyn, M. J., et al. (2024) · Nature Structural & Molecular Biology · doi:10.1038/s41594-023-01184-4 · Cited by 52
Rimbert, A., Dalila, N., Wolters, J. C., Huijkman, N., Smit, M., Kloosterhuis, N., Riemsma, M., van der Veen, Y., Singla, A., van Dijk, F., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz727 · Cited by 24
What does genetics tell us about imprinting and the placenta connection?
Varmuza, S., & Miri, K. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1714-0 · Cited by 22
Metadata
- Authors
- van de Sluis, B., Muller, P., Duran, K., Chen, A., Groot, A. J., Klomp, L. W., Liu, P. P., & Wijmenga, C.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 2007-06-01
- Volume
- 27
- Issue
- 11
- Pages
- 4142-4156
- ISSN
- 1098-5549
- Cited by
- 105
- References
- 3
- Language
- en
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