What does genetics tell us about imprinting and the placenta connection?

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Placental-specific IGF-II is a major modulator of placental and fetal growth

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The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

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Altered microtubule organization in small-calibre axons of mice lacking tau protein

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Role of paternal and maternal genomes in mouse development

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Differential activity of maternally and paternally derived chromosome regions in mice

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Genomic Imprinting in MammalsPreprint

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Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

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Genomic Imprinting Disrupted by a Maternal Effect Mutation in the Dnmt1 Gene

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A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints

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In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control Regions

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Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.Preprint

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Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

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PGC7/Stella protects against DNA demethylation in early embryogenesis

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Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest

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Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

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Contribution of Intragenic DNA Methylation in Mouse Gametic DNA Methylomes to Establish Oocyte-Specific Heritable Marks

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Parent-Specific Gene Expression and the Triploid Endosperm

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Regulation of Maternal Behavior and Offspring Growth by Paternally Expressed Peg3

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Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

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Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.Preprint

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Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans

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Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1

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Zac1 Regulates an Imprinted Gene Network Critically Involved in the Control of Embryonic Growth

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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

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Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality

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A Large Imprinted microRNA Gene Cluster at the Mouse Dlk1-Gtl2 Domain

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Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation

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Methylation Dynamics of Imprinted Genes in Mouse Germ Cells

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Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes

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Variable and tissue-specific hormone resistance in heterotrimeric G s protein α-subunit (G s α) knockout mice is due to tissue-specific imprinting of the G s α gene

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Functional analysis of secreted and transmembrane proteins critical to mouse development.

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Dynamic chromatin modifications characterise the first cell cycle in mouse embryos

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Genomic imprinting of Mash2, a mouse gene required for trophoblast development

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Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishmentPreprint

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Transcription is required for establishment of germline methylation marks at imprinted genesPreprint

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Type 3 deiodinase is critical for the maturation and function of the thyroid axis

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The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

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A mouse knockout library for secreted and transmembrane proteins

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Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta

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The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta

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The Dlk1 and Gtl2 genes are linked and reciprocally imprintedPreprint

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Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice

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A mouse model for Prader-Willi syndrome imprinting-centre mutations

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Transgenic RNAi Reveals Essential Function for CTCF in H19 Gene Imprinting

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Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

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Mirror Syndrome: A Systematic Review of Fetal Associated Conditions, Maternal Presentation and Perinatal Outcome

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Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies

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Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

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Phenotypic alterations in insulin-deficient mutant mice

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The imprinted signaling protein XLαs is required for postnatal adaptation to feeding

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Deficiency in the Organic Cation Transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in Mice Abolishes Renal Secretion of Organic Cations

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Oocyte growth‐dependent progression of maternal imprinting in mice

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Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci

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Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo

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Genomic Imprinting: A Mammalian Epigenetic Discovery Model

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Mutations Causing Familial Biparental Hydatidiform Mole Implicate C6orf221 as a Possible Regulator of Genomic Imprinting in the Human Oocyte

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Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2

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Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element.Preprint

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Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: Evidence for altered striatal function

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The imprinted gene Magel2 regulates normal circadian output

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Normal postimplantation development of mouse parthenogenetic embryos to the forelimb bud stage

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Hypomethylation at multiple maternally methylated imprinted regions including PLAGL1 and GNAS loci in Beckwith–Wiedemann syndrome

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Critical Evaluation of Imprinted Gene Expression by RNA–Seq: A New Perspective

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Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice

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Delta-like and Gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12

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The epigenetic imprinting defect of patients with Beckwith—Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region

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The transmembrane protein TMEM16A is required for normal development of the murine trachea

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Placental overgrowth in mice lacking the imprinted gene Ipl

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New insights into establishment and maintenance of DNA methylation imprints in mammals

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Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting

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Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3

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Disruption of the mouse necdin gene results in early post-natal lethality

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Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo

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Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster

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Site-Specific Silencing of Regulatory Elements as a Mechanism of X Inactivation

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Transcriptome-Wide Identification of Novel Imprinted Genes in Neonatal Mouse Brain

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Identification of a Methylation Imprint Mark within the Mouse Gnas Locus

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TASK Channels Determine pH Sensitivity in Select Respiratory Neurons But Do Not Contribute to Central Respiratory Chemosensitivity

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G9a Histone Methyltransferase Contributes to Imprinting in the Mouse Placenta

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The origin and evolution of genomic imprinting and viviparity in mammals

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Deletion of the MBII-85 snoRNA Gene Cluster in Mice Results in Postnatal Growth Retardation

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Identification of Novel Imprinted Genes in a Genome-Wide Screen for Maternal MethylationPreprint

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Global Survey of Genomic Imprinting by Transcriptome Sequencing

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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.

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Regulation of alternative polyadenylation by genomic imprintingPreprint

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p57Kip2 regulates the proper development of labyrinthine and spongiotrophoblasts

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Genomic imprinting — defusing the ovarian time bomb

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Genetic and Epigenetic Analysis of Recurrent Hydatidiform Mole

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Placental growth retardation due to loss of imprinting of Phlda2

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Deficiency in p57Kip2 expression induces preeclampsia-like symptoms in mice

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Temporal and spatial regulation of H19 imprinting in normal and uniparental mouse embryos

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Expression Analysis of the NLRP Gene Family Suggests a Role in Human Preimplantation Development

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Imprinted genes and the epigenetic regulation of placental phenotype

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The Cell Adhesion Molecule M-Cadherin Is Not Essential for Muscle Development and Regeneration

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DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial

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Two distinct mechanisms of silencing by the KvDMR1 imprinting control region

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The Imprinted Phlda2 Gene Regulates Extraembryonic Energy Stores

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A recurrent intragenic genomic duplication, other novel mutations in NLRP7 and imprinting defects in recurrent biparental hydatidiform moles

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Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice

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5-HT2Areceptors: location and functional analysis in intestines of wild-type and 5-HT2Aknockout mice

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Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse

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A Screen for Retrotransposed Imprinted Genes Reveals an Association between X Chromosome Homology and Maternal Germ-Line Methylation

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MeCP2-dependent repression of an imprinted miR-184 released by depolarization

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DNA Methylation Is Dispensable for the Growth and Survival of the Extraembryonic Lineages

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Sequence and Comparative Analysis of the Mouse 1-Megabase Region Orthologous to the Human 11p15 Imprinted DomainPreprint

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Epigenetic Properties and Identification of an Imprint Mark in the Nesp-Gnasxl Domain of the Mouse Gnas Imprinted Locus

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Imprinting of a RING zinc-finger encoding gene in the mouse chromosome region homologous to the Prader–Willi syndrome genetic region

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Increased Activity of Hypoxia-Inducible Factor 1 Is Associated with Early Embryonic Lethality in Commd1 Null Mice

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The SNRPN promoter is not required for genomic imprinting of the Prader-Willi/Angelman domain in mice

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Rasgrf1 Imprinting Is Regulated by a CTCF-Dependent Methylation-Sensitive Enhancer Blocker

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Imprinted gene in postnatal growth role

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IMPT1, an imprinted gene similar to polyspecific transporter and multi- drug resistance genes

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Screening for imprinted genes by allelic message display: Identification of a paternally expressed gene Impact on mouse chromosome 18

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Loss of the maternal imprint in Dnmt3L mice leads to a differentiation defect in the extraembryonic tissue

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A Survey for Novel Imprinted Genes in the Mouse Placenta by mRNA-seq

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The specification of imprints in mammals

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Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation

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Lack of Pwcr1/MBII-85 snoRNA is critical for neonatal lethality in Prader–Willi syndrome mouse models

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Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity

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Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2 / Tfpi2 , which requires EHMT2 and EED for allelic-silencingPreprint

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Imprinted genes in mouse placental development and the regulation of fetal energy stores

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Different mechanisms cause imprinting defects at the IGF2/H19 locus in Beckwith-Wiedemann syndrome and Wilms' tumour

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Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4Preprint

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Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies

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The Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses

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Identification of a New Imprinted Gene, Rian, on Mouse Chromosome 12 by Fluorescent Differential Display Screening

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Non-conflict theories for the evolution of genomic imprinting

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Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regionsPreprint

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PGC7 suppresses TET3 for protecting DNA methylation

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Inpp5f Is a Polyphosphoinositide Phosphatase That Regulates Cardiac Hypertrophic Responsiveness

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Methylation at mouse Cdkn1c is acquired during postimplantation development and functions to maintain imprinted expression

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Lineage-specific imprinting and evolution of the zinc-finger gene ZIM2

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Frat is dispensable for canonical Wnt signaling in mammalsPreprint

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Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

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Transcript- and tissue-specific imprinting of a tumour suppressor gene

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The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues

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Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model

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DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition

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Conditional deletions refine the embryonic requirement for Dlk1

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Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs

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Mit1/Lb9andCopg2, new members of mouse imprinted genes closely linked toPeg1/Mest

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Imprinting at the MouseIns2Locus: Evidence forcis- andtrans-Allelic Interactions

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The imprinted polycomb group gene Sfmbt2 is required for trophoblast maintenance and placenta development

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A distinct microvascular endothelial gene expression profile in severe IUGR placentas

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Lack of Reciprocal Genomic Imprinting of Sense and Antisense RNA of Mouse Insulin-like Growth Factor II Receptor in the Central Nervous System1

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Importance of the matriline for genomic imprinting, brain development and behaviour

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Imprinting and Evolution of Two Kruppel-type Zinc-Finger Genes, ZIM3 and ZNF264, Located in the PEG3/USP29 Imprinted Domain

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The Imprinted Oedematous-Small Mutation on Mouse Chromosome 2 Identifies New Roles for Gnas and Gnasxl in Development

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Chromatin regulators of genomic imprinting

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Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency

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Identification of Jade1, a Gene Encoding a PHD Zinc Finger Protein, in a Gene Trap Mutagenesis Screen for Genes Involved in Anteroposterior Axis Development

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Structural characterization of Rasgrf1 and a novel linked imprinted locus

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Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo

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Mapping and identification of candidate loci responsible for Peromyscus hybrid overgrowth

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Exclusive paternal expression and novel alternatively spliced variants of ε‐sarcoglycan mRNA in mouse brain

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Establishment of the primary imprint of the HYMAI/PLAGL1 imprint control region during oogenesis

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The Oocyte-Specific Methylated Region of the U2afbp-rs/U2af1-rs1 Gene Is Dispensable for Its Imprinted Methylation

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