The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.
Open accessAbstract
The retinoblastoma protein interacts with a number of cellular proteins to form complexes which are probably crucial for its normal physiological function. To identify these proteins, we isolated nine distinct clones by direct screening of cDNA expression libraries using purified RB protein as a probe. One of these clones, Ap12, is expressed predominantly at the G1-S boundary and in the S phase of the cell cycle. The nucleotide sequence of Ap12 has features characteristic of transcription factors. The C-terminal region binds to unphosphorylated RB in regions similar to those to which T antigen binds and contains a transactivation domain. A region containing a potential leucine zipper flanked by basic residues is able to bind an E2F recognition sequence specifically. Expression of Ap12 in mammalian cells significantly enhances E2F-dependent transcriptional activity. These results suggest that Ap12 encodes a protein with properties known to be characteristic of transcription factor E2F.
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Cites
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
Landschulz, W. H., Johnson, P. F., & McKnight, S. L. (1988) · Science · doi:10.1126/science.3289117 · Cited by 3,443
The human papilloma virus-16 E7-oncoprotein is able to bind to the retinoblastoma gene product
Dyson, N., Howley, P. M., Münger, K., & Harlow, E. (1989) · Science · doi:10.1126/science.2537532 · Cited by 3,017
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
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Self-citationDeCaprio, J. A., Ludlow, J. W., Lynch, D., Furukawa, Y., Griffin, J., Piwnica-Worms, H., Huang, C.-M., & Livingston, D. M. (1989) · Cell · doi:10.1016/0092-8674(89)90507-2 · Cited by 897
Cited by
The regulation of E2F by pRB-family proteins.
Dyson, N. (1998) · Genes & Development · doi:10.1101/gad.12.15.2245 · Cited by 2,317
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
Durfee, T., Becherer, K., Chen, P. L., Yeh, S. H., Yang, Y., Kilburn, A. E., Lee, W. H., & Elledge, S. J. (1993) · Genes & Development · doi:10.1101/gad.7.4.555 · Cited by 1,451
Self-citationSibling rivalry in the E2F family
Trimarchi, J. M., & Lees, J. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm714 · Cited by 1,158
Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1
Yamasaki, L., Jacks, T., Bronson, R., Goillot, E., Harlow, E., & Dyson, N. J. (1996) · Cell · doi:10.1016/s0092-8674(00)81254-4 · Cited by 698
The E2F family: specific functions and overlapping interests
Attwooll, C., Denchi, E. L., & Helin, K. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600481 · Cited by 573
Metadata
- Authors
- Shan, B., Zhu, X., Chen, P. L., Durfee, T., Yang, Y., Sharp, D., & Lee, W. H.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1992-12
- Volume
- 12
- Issue
- 12
- Pages
- 5620-5631
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1873059808
- Cited by
- 330
- References
- 6
- FWCI
- 18.27
- Type
- journal article
- Language
- en
- Open access
- green
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- Shan, B., Zhu, X., Chen, P. L., Durfee, T., Yang, Y., Sharp, D., & Lee, W. H. (1992). Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.12.12.5620
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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