Sibling rivalry in the E2F family

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Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1

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The E2F1–3 transcription factors are essential for cellular proliferation

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A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

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Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis

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Deregulated Expression of E2F-1 Induces S-Phase Entry and Leads to Apoptosis

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Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice

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Regulation of cell proliferation by the E2F transcription factors

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Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein

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Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.Preprint

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The Retinoblastoma Protein Binds to a Family of E2F Transcription Factors

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Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.

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Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes

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Shared role of the pRB-related p130 and p107 proteins in limb development.Preprint

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E2F3 activity is regulated during the cell cycle and is required for the induction of S phasePreprint

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The retinoblastoma protein pathway and the restriction point

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Cell cycle regulation of the human cdc2 gene.

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PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2APreprint

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Mutation of E2f-1 Suppresses Apoptosis and Inappropriate S Phase Entry and Extends Survival of Rb-Deficient Mouse Embryos

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The Retinoblastoma Protein Acts as a Transcriptional Coactivator Required for Osteogenic Differentiation

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Mechanisms of transcriptional memory

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E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.

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An E2F‐binding site mediates cell‐cycle regulated repression of mouse B‐myb transcription.

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Targeted disruption of p107: functional overlap between p107 and Rb.Preprint

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E2f3 is critical for normal cellular proliferationPreprint

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The retinoblastoma gene family: cousins with overlapping interests

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A common E2F-1 and p73 pathway mediates cell death induced by TCR activation

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Molecular Cloning of Cellular Genes Encoding Retinoblastoma-Associated Proteins: Identification of a Gene with Properties of the Transcription Factor E2F

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E2F-4 Switches from p130 to p107 and pRB in Response to Cell Cycle Reentry

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CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.Preprint

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E2F Repression by C/EBPα Is Required for Adipogenesis and Granulopoiesis In Vivo

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Deregulated Expression of E2F Family Members Induces S-Phase Entry and Overcomes p16 INK4A -Mediated Growth Suppression

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E2F4 and E2F5 Play an Essential Role in Pocket Protein–Mediated G1 Control

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Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members.Preprint

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Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/−) mice

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction.Preprint

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A new component of the transcription factor DRTF1/E2F

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Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members

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Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance.

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The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

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Myc Requires Distinct E2F Activities to Induce S Phase and Apoptosis

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.Preprint

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BRG-1 is required for RB-mediated cell cycle arrest

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Functional synergy between DP‐1 and E2F‐1 in the cell cycle‐regulating transcription factor DRTF1/E2F.

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Oncogenic capacity of the E2F1 gene.

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In Vivo Association of E2F and DP Family Proteins

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A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.

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Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter.Preprint

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E2F-1 Potentiates Cell Death by Blocking Antiapoptotic Signaling Pathways

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Target gene specificity of E2F and pocket protein family members in living cells

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E2F-5, a New E2F Family Member That Interacts with p130 In Vivo

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E2F Activity Is Regulated by Cell Cycle-Dependent Changes in Subcellular Localization

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E2F-6, a member of the E2F family that can behave as a transcriptional repressor

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Transcriptional Repression by the Retinoblastoma Protein through the Recruitment of a Histone Methyltransferase

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Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

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E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.Preprint

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Overexpression of E2F‐1 in rat embryo fibroblasts leads to neoplastic transformation.

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Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6.

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E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in <i>Rb</i> mutant embryos

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What does ‘chromatin remodeling’ mean?

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Key Roles for E2F1 in Signaling p53-Dependent Apoptosis and in Cell Division within Developing Tumors

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