The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Instability of simple sequence DNA in Saccharomyces cerevisiae.
Open accessAbstract
All eukaryotic genomes thus far examined contain simple sequence repeats. A particularly common simple sequence in many organisms (including humans) consists of tracts of alternating GT residues on one strand. Allelic poly(GT) tracts are often of different lengths in different individuals, indicating that they are likely to be unstable. We examined the instability of poly(GT) and poly(G) tracts in the yeast Saccharomyces cerevisiae. We found that these tracts were dramatically unstable, altering length at a minimal rate of 10(-4) events per division. Most of the changes involved one or two repeat unit additions or deletions, although one alteration involved an interaction with the yeast telomeres.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The distribution of the numbers of mutants in bacterial populations
Lea, D. E., & Coulson, C. A. (1949) · Journal of Genetics · doi:10.1007/bf02986080 · Cited by 1,450
Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1966.031.01.014 · Cited by 1,400 · cited 2×
“The alternative mechanism to explain tract instability is DNA polymerase slippage (43).”
BackgroundDNA sequences of telomeres maintained in yeast
Shampay, J., Szostak, J. W., & Blackburn, E. H. (1984) · Nature · doi:10.1038/310154a0 · Cited by 551
Cited by
Strand, M., Prolla, T. A., Liskay, R. M., & Petes, T. D. (1993) · Nature · doi:10.1038/365274a0 · Cited by 1,077
Self-citationShort-sequence DNA repeats in prokaryotic genomes
van Belkum, A., Scherer, S., van Alphen, L., & Verbrugh, H. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.275-293.1998 · Cited by 737
A genome-wide view of the spectrum of spontaneous mutations in yeast.
Lynch, M., Sung, W., Morris, K., Coffey, N., Landry, C. R., Dopman, E. B., Dickinson, W. J., Okamoto, K., Kulkarni, S., Hartl, D. L., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803466105 · Cited by 708
Microsatellite mutations in the germline:
Ellegren, H. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)02139-9 · Cited by 676
Kruglyak, S., Durrett, R. T., Schug, M. D., & Aquadro, C. F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10774 · Cited by 437
Metadata
- Authors
- Henderson, S. T., & Petes, T. D.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1992-06
- Volume
- 12
- Issue
- 6
- Pages
- 2749-2757
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W2179032951
- Cited by
- 237
- References
- 3
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Instability of simple sequence DNA in Saccharomyces cerevisiae. https://app.cochat.ai/papers/10.1128/mcb.12.6.2749
- The paper
- Henderson, S. T., & Petes, T. D. (1992). Instability of simple sequence DNA in Saccharomyces cerevisiae. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.12.6.2749
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
