Cellular Transformation and Malignancy Induced by ras Require c-jun

Johnson, Randall, Spiegelman, Bruce, Hanahan, Douglas, Wisdom, Ron·1996·Molecular and Cellular Biology

Cited by (281)

Items 201–281 of 281

  1. c-JUN prevents methylation of p16INK4a (and Cdk6): the villain turned bodyguard
    Karoline Kollmann, Gerwin Heller, Veronika Sexl · 2011 · Oncotarget
  2. Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes
    Binbin Li, Zheng Wan, Guoliang Huang, Zunnan Huang, Xiangning Zhang, Dan Kui Liao, Shengqun Luo, Zhiwei He · 2015 · BMC Cancer
  3. A JNK-Independent Signaling Pathway Regulates TNFα-Stimulated, c-Jun-Driven FRA-1 Protooncogene Transcription in Pulmonary Epithelial Cells
    Pavan P. Adiseshaiah, Dhananjaya V. Kalvakolanu, Sekhar P. Reddy · 2006 · The Journal of Immunology
  4. Cellular processes of v-Src transformation revealed by gene profiling of primary cells - Implications for human cancer
    Bart M. Maślikowski, Benjamin Néel, Ying Wu, Lizhen Wang, Natalie Rodrigues, Germain Gillet, Pierre‐André Bédard · 2010 · BMC Cancer
  5. Heregulin-β promotes matrix metalloproteinase-7 expression via HER2-mediated AP-1 activation in MCF-7 cells
    Guogang Yuan, Qian Lü, Lun Song, Ming Shi, Dan Li, Ming Yu, Meiru Hu, Beifen Shen, Ning Guo · 2008 · Molecular and Cellular Biochemistry
  6. c-Jun controls the efficiency of MAP kinase signaling by transcriptional repression of MAP kinase phosphatases
    Amy E. Sprowles, Dan R. Robinson, Yi-Mi Wu, Hsing-Jien Kung, Ron Wisdom · 2005 · Experimental Cell Research
  7. The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors
    Janice M. Kraniak, Daochun Sun, Raymond R. Mattingly, John J. Reiners, Michael A. Tainsky · 2010 · Molecular and Cellular Biochemistry
  8. Repeated H2O2 exposure drives cell cycle progression in an in vitro model of ulcerative colitis
    Angela Poehlmann, Kathrin Reißig, Peter Schönfeld, Diana Walluscheck, Antje Schinlauer, Roland Hartig, Wiebke Lessel, Thomas Guenther, Andrew R. Silver, Albert Roessner · 2013 · Journal of Cellular and Molecular Medicine
  9. TAF4b and Jun/Activating Protein-1 Collaborate to Regulate the Expression of Integrin α6 and Cancer Cell Migration Properties
    Μαργαρίτα Καλογεροπούλου, Angeliki Voulgari, Vassiliki Kostourou, Raphael Sandaltzopoulos, Rivka Dikstein, Irwin Davidson, Làszlò Tora, Alexander Pintzas · 2010 · Molecular Cancer Research
  10. A selective small‐molecule inhibitor of c‐Jun N‐terminal kinase 1
    Ke Yao, Yong‐Yeon Cho, Ann M. Bode, Anuradha Vummenthala, Jewn Giew Park, Kangdong Liu, Yuan‐Ping Pang, Zigang Dong · 2009 · FEBS Letters
  11. One-step discrimination of BCR/ABLp210 transcript isoforms directly from RNA extraction with fusion-triggered rolling circle amplification
    Nini Luo, Qianfeng Xia, Lutan Zhang, Yuhong Zhang, Lizhen Huang, Yangli Zhang, Jie Zhao, Shijia Ding, Wei Cheng · 2019 · Analytica Chimica Acta
  12. Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9
    Simon · 2010 · International Journal of Oncology
  13. Fra-1 Expression in Malignant and Benign Thyroid Tumor
    Yong Hyun Kim, Jeong Heon Oh, Nan Hee Kim, Kyung Mook Choi, Sang Jin Kim, Sei Hyun Baik, Dong Seop Choi, Eung Seok Lee · 2001 · The Korean Journal of Internal Medicine
  14. The Role of sLZIP in Transcriptional Regulation of c-Jun and Involvement in Migration and Invasion of Cervical Cancer Cells
    Eunsoo Park, Hyereen Kang, Jeonghan Kim, Jesang Ko · 2014 · Cellular Physiology and Biochemistry
  15. Cloning Oncogenic Ras-Regulated Genes by Differential Display
    Hakryul Jo, Hong Zhang, Rong Zhang, Peng Liang · 1998 · Methods
  16. 5′‐Nitro‐indirubinoxime inhibits epidermal growth factor‐ and phorbol ester‐induced AP‐1 activity and cell transformation through inhibition of phosphorylation of Pin1
    Prem Khanal, Hoo‐Kyun Choi, Gwang Mo Namgoong, Sang‐Gun Ahn, Jimin Yoon, Honglae Sohn, Hong Seok Choi · 2011 · Molecular Carcinogenesis
  17. Oncogenes as Novel Targets for Cancer Therapy (Part III)
    Zhuo Zhang, M. Li, Elizabeth R. Rayburn, Donald L. Hill, Ruiwen Zhang, Hui Wang · 2005 · American Journal of PharmacoGenomics
  18. cDNA array analyses of K-ras-induced gene transcription
    Gaston G. M. Habets, Marc Knepper, Jaina Sumortin, Yun-Jung Choi, Takehiko Sasazuki, Senji Shirasawa, Gideon E. Bollag · 2001 · Methods in enzymology on CD-ROM/Methods in enzymology
  19. Ets2 is not required for Ras or Neu/ErbB-2 mediated cellular transformation in vitro
    Anikó Hevér, Robert G. Oshima, Craig A. Hauser · 2003 · Experimental Cell Research
  20. Clinical activity of tipifarnib in hematologic malignancies
    Elias Joseph Jabbour, Hagop M. Kantarjian, Jörge E. Cortes · 2007 · Expert Opinion on Investigational Drugs
  21. The development of protein farnesyltransferase and other ras-directed therapeutics for malignant diseases
    Eric Keith Rowinsky, Amita Patnaik · 2000 · Emerging Drugs
  22. Oncogenic N-Ras Stimulates SRF-Mediated Transactivation via H3 Acetylation at Lysine 9
    Sun-Ju Yi, Seong Yun Hwang, Myung-Ju Oh, Yang‐Hoon Kim, Hojin Ryu, Sung‐Keun Rhee, Byung Hak Jhun, Kyunghwan Kim · 2018 · BioMed Research International
  23. Multi-omics analysis revealed crucial genes and pathways associated with black carp antiviral innate immunity
    Ji Liu, Yujie Yan, Jun Yan, Junting Wang, Jing Wei, Jun Xiao, Yong Zeng, Hao Feng · 2020 · Fish & Shellfish Immunology
  24. Stimulation of T cells up-regulates expression of Ifi202, an interferon-inducible lupus susceptibility gene, through activation of JNK/c-Jun pathway
    Jianming Chen, Ravichandran Panchanathan, Divaker Choubey · 2008 · Immunology Letters
  25. JunD-Menin Interaction Regulates c-Jun-mediated AP-1 Transactivation
    YASUTO IKEO, Wataru Yumita, Akihiro Sakurai, Kiyoshi Hashizume · 2004 · Endocrine Journal
  26. Ras Protects Rb Family Null Fibroblasts from Cell Death
    Arthur P. Young, Gregory D. Longmore · 2004 · Journal of Biological Chemistry
  27. c-jun Cooperates with SV40 T-Antigen to Sustain MMP-2 Expression in Immortalized Cells
    Keith R. Laderoute, Joy M. Calaoagan, A.Merrill Knapp, Holly L. Mendonca, Randall S. Johnson · 2001 · Biochemical and Biophysical Research Communications
  28. Life and death in the JUNgle
    Jonathan B Weitzman · 2001 · Trends in Molecular Medicine
  29. Hyperphosphorylation of extracellular regulated kinase 2 (ERK2) and inhibition of JNK2 phosphorylation are associated with increased S‐phase during transformation of Syrian hamster embryo cells by Malachite Green
    Bipasha Bose, Rekha R. Gour, Leena Motiwale, Sanjay Gupta, K.V.K. Rao · 2004 · Cell Biology International
  30. Krüppel‐like factor 6 interferes with cellular transformation induced by the H‐ ras oncogene
    Lucas Daniel Trucco, Verónica Andreoli, Nicolás Gonzalo Núñez, Mariana Maccioni, José Luís Bocco · 2014 · The FASEB Journal
  31. JNK: A double-edged sword in tumorigenesis
    Francisco Javier Cubero, Gang Zhao, Christian Trautwein, Kris V. Kowdley, Geoffrey William McCaughan, Christian Trautwein · 2011 · Hepatology
  32. JNK inhibitor IX restrains pancreatic cancer through p53 and p21
    Jingwei Shi, Xing Yang, Qi Kang, Jian Lu, Maximilian Denzinger, Marko Kornmann, Benno Traub · 2022 · Frontiers in Oncology
  33. Ras-Mediated Deregulation of Gene Expression and Contribution to Oncogenesis
    Gretchen A. Murphy, Channing J. Der · 2003 · Humana Press eBooks
  34. Pleiotropic Action of AP-1 in v-Src-Transformed Cells
    Lizhen Wang, Natalie Rodrigues, Ying Wu, Bart M. Maślikowski, Nishi Nihar Singh, Samantha Lacroix, Pierre‐André Bédard · 2011 · Journal of Virology
  35. Stress-activated kinases as therapeutic targets in pancreatic cancer
    Benno Traub, Aileen Roth, Marko Kornmann, Uwe Knippschild, Joachim Bischof · 2021 · World Journal of Gastroenterology
  36. JunD/AP-1 Antagonizes the Induction ofDAPK1To Promote the Survival of v-Src-Transformed Cells
    Bart M. Maślikowski, Lizhen Wang, Ying Wu, Ben D. Fielding, Pierre‐André Bédard · 2016 · Journal of Virology
  37. The role of c-Jun for beating cardiomycyte formation in prepared embryonic body
    Lide Su, Guofu Zhang, Lili Jiang, Chao Chi, Bing Bai, Kai Kang · 2023 · Stem Cell Research & Therapy
  38. Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer
    Martina Tinzl, Binshen Chen, Shaoyong Chen, Julius Semenas, Per‐Anders Abrahamsson, Nishtman Dizeyi · 2013 · PLoS ONE
  39. The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts
    Mark Gagliardi, Scott Maynard, Bojana Bojović, Pierre‐André Bédard · 2001 · Oncogene
  40. The Interruption of PKC-ι Signaling and TRAIL Combination Therapy Against Glioblastoma Cells
    Andrea N. McCray, Shraddha Desai, Mildred E. Acevedo-Duncan · 2014 · Neurochemical Research
  41. Harvey-ras Gene Expression and Epidermal Cell Proliferation in Dibenzo[a,l]Pyrene-Treated Early Preneoplastic SENCAR Mouse Skin
    Gausal Azam Khan, Gautam Bhattacharya, Paula C. Mailander, Jane L. Meza, Laura A. Hansen, Dhrubajyoti Chakravarti · 2005 · Journal of Investigative Dermatology
  42. Mechanisms of Regulation of Taurine Transporter Activity
    Xiaobin Han, Russell W. Chesney · 2006 · Springer eBooks
  43. Differential Regulation of MAPK (JNK 3) Gene Expression in Human Head and Neck Squamous Cell Carcinomas
    Tibor Görögh, J. Berwig, Nina Scola, Beatrix Lippert · 2004 · Oncology Research and Treatment
  44. Differential display analysis of gene expression altered by ras oncogene
    Hakryul Jo, Yong–Jig Cho, Hong Zhang, Peng Liang · 2001 · Methods in enzymology on CD-ROM/Methods in enzymology
  45. Signal Transduction in Fibroblasts Stably Transformed by [Val12]Ras
    Sofia Ljungdahl, Stig Linder, Kerstin Sollerbrant, Catharina Svensson, Maria Caspar Shoshan · 1997 · European Journal of Biochemistry
  46. The Multi-Gene Family of Transcription Factor AP-1
    Peter E. Angel, Jochen Heß · 2010 · Elsevier eBooks
  47. The splice 1 variant of HTLV-1 bZIP factor stabilizes c-Jun
    Nicholas J. Polakowski, Martin Pearce, Oppah Kuguyo, Georgina Boateng, Kimson Hoang, Isabelle Lemasson · 2020 · Virology
  48. Activating transcription factor 2 targets c‐Fos, but not c‐Jun, in growth plate chondrocytes
    Xinying Li, Phyllis A. Luvalle · 2010 · Journal of Cellular Biochemistry
  49. Jun: the master regulator in healthy and cancer cells
    Petr Vaňhara, Jan Šmarda · 2006 · Journal of Applied Biomedicine
  50. c-Jun: A Complex Tale of a Simple Transcription Factor
    Ying Xia · 2007 · Springer eBooks
  51. Positive Mediators of Cell Proliferation in Neoplastic Transformation
    James N. Welch, Susan A. Chrysogelos · 2002 · Humana Press eBooks
  52. The Role of Histone Demethylases in Disease
    Paul A. Cloos · 2011 · Springer eBooks
  53. Short Communication b-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer
    Thomas Brabletz, Andreas Jung, Serpil DAĞ, Falk Hlubek, Thomas Kirchner · 1999
  54. The molecular mechanism underlying KRAS regulation on STK31 expression in pancreatic ductal adenocarcinoma
    Yuting Liu, Shing Chun Tang, Chi Han Li, Ka Fai To, Bo Li, Stephen Lam Chan, Chi Hin Wong, Yangchao Chen · 2024 · Cancer Science
  55. Novel MLLCBP fusion transcript in therapy‐related chronic myelomonocytic leukemia with a t(11;16) (q23;p13) chromosome translocation
    Noriko Satake, Yasushi Ishida, Yoshiko Otoh, Shin‐ichi Hinohara, Hirofumi Kobayashi, Akiko Sakashita, Nobuo Maseki, Yasuhiko Kaneko · 1997 · Genes Chromosomes and Cancer
  56. [Phosphoproteomic analysis of human umbilical venous endothelial cells with DENV-2 infection].
    Pan Hu, Y Cheng, Yuanyi Wang, Xiaoqin Gou, H Liu, Li Zuo, N Wu · 2023 · PubMed Central
  57. Activator protein-1 in liver pathology: from precancerous diseases to hepatocellular carcinoma
    Fernanda Villarruel-Melquiades, Isaac Aguirre-Maldonado, Ema Elvira Herrera-López, María Eugenia Mendoza‐Garrido, Julio Isael Pérez‐Carreón, Cecilia Bañuelos, Javier Camacho · 2024 · Hepatoma Research
  58. Hepatocyte Growth, Proliferation and Experimental Carcinogenesis
    Giovanna Maria Ledda‐Columbano, Amedeo Columbano · 2010 · Molecular pathology library
  59. Cytokine Receptors
    Alison McFarlane, Paul K. Fyfe, Ignacio Moraga · 2021 · Elsevier eBooks
  60. Ações antagônicas de FGF2 em células tumorais de camundongo: disparo de mitogênese e de morte celular
    Erico Tosoni Costa · 2005
  61. Multigene Family of Transcription Factor AP-1
    Peter E. Angel · 2003 · Elsevier eBooks
  62. JUN
    Robin Hesketh · 1997 · Elsevier eBooks
  63. Review Article Aberration in Signal Transduction Pathway in Human T-Cell Leukemia Virus Type I-Infected T Cells
    Naoki Mori, Masahiko Fujii, Naoki Yamamoto · 2000 · Institutional Repositories DataBase (IRDB)
  64. Inflammation and host-microbe signaling in the development and progression of colorectal carcinoma
    Yinghui Li · 2013 · Figshare
  65. Mouse Models to Study Pro-and Antiangiogenic Potential: Novel Roles for PLGF and FLT1
    Lieve Moons, Aernout Luttun, Peter Carmeliet, Ed Conway · 2004 · Basic science for the cardiologist
  66. HYALURONAN STIMULATES KERATINOCYTE MIGRATION AND ACTIVATES THE TRANSCRIPTION FACTOR AP-1 IN KERATINOCYTES THROUGH THE JNK PATHWAY
    Kari Törrönen, Monica Yabal, Kirsi J. Rilla, Kai Kaarniranta, Raija Tammi, Mikko Juhani Lammi, Markku Tammi · 2002 · Elsevier eBooks
  67. Role and Function of c-Jun Protein Complex in Cancer Cell Behavior
    Antoine Mialon · 2009 · UTUPub (University of Turku)
  68. Three down and counting: the transformation of human mammary cells from normal to malignant in three steps
    Jonathan B Weitzman · 2001
  69. The role of JIP-1 in JNK signalling during stress and apoptosis
    Mahesh Vaishnav · 2002 · Figshare
  70. Induction of c-Jun Expression by Breast Cancer Anti-estrogen Resistance-3 (BCAR3) in Human Breast MCF-12A Cells
    Myung-Ju Oh, Jihyun Kim, Byung Hak Jhun · 2016 · Journal of Life Science
  71. The expression of cardiotrophin-1 is differentially regulated in murine and human obesity type II diabetes
    Kelesha Sarjeant · 2011
  72. Nuclear NFATc1/Smad3 complexes in Smad4-deficient pancreatic cancer
    Marie C. Hasselluhn · 2019
  73. c-Jun and its targets in fibrosarcoma and melanoma cells
    Mari Kielosto · 2020 · Työväentutkimus Vuosikirja
  74. WITHDRAWN: Knocking out c-Jun promotes cardiomyocyte differentiation from embryonic stem cells
    Lide Su, Guofu Zhang, Hui Zhong, Ling Luo, Yan Li, Chao Chi, Lili Jiang, Ping Huang, Guihuan Liu, Ping Zhu et al. · 2021 · International Journal of Cardiology · Retracted
  75. Faculty Opinions recommendation of Suppression of Ras-stimulated transformation by the JNK signal transduction pathway.
    Ron Prywes · 2003 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  76. Involvement of Mitogen-Activated Protein (MAP) Kinase Pathway in the Etiopathogenesis of Cancer and Its Role in Cancer Therapeutics
    Nusrat Nabi, Peerzadi Mehakshan Shafat, Shareen Bashir, Mosin Saleem Khan · 2025 · Springer eBooks
  77. Signal Regulated Gene Expression Mediated by Transcription Factors-Members of AP-1 and ETS/SRF Family Members: Pathways for Potential Therapeutic Intervention
    Alex Pintzas · 2003 · NATO science series. Series II, Mathematics, physics and chemistry
  78. Additional file 1 of The role of c-Jun for beating cardiomycyte formation in prepared embryonic body
    Su, Lide, Guofu Zhang, Jiang, Lili, Chao Chi, Bai, Bing, Kang, Kai · 2023 · Figshare
  79. Impact of LYL1 deficiency on adipocyte differentiation
    Abid Hussain · 2015 · theses.fr (ABES)
  80. c-Jun N-Terminal Kinase: A Spatiotemporal Regulator of Cell Fate and Function
    Seth Thesing, Mohammed Salahuddin, Emily Okonek, Ryan L. Hanson · 2026 · Biology
  81. Role of the cJun NH2-Terminal Kinase (JNK) in Cancer: A Dissertation
    Cristina Cellurale · 2010 · eScholarship@UMassChan