The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Targeted Disruption of Mouse Yin Yang 1 Transcription Factor Results in Peri-Implantation Lethality
Open accessAbstract
Yin Yang 1 (YY1) is a zinc finger-containing transcription factor and a target of viral oncoproteins. To determine the biological role of YY1 in mammalian development, we generated mice deficient for YY1 by gene targeting. Homozygosity for the mutated YY1 allele results in embryonic lethality in the mouse. YY1 mutants undergo implantation and induce uterine decidualization but rapidly degenerate around the time of implantation. A subset of YY1 heterozygote embryos are developmentally retarded and exhibit neurulation defects, suggesting that YY1 may have additional roles during later stages of mouse embryogenesis. Our studies demonstrate an essential function for YY1 in the development of the mouse embryo.
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Cites
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Cited by
Chromatin modification and epigenetic reprogramming in mammalian development
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Self-citationTranscriptional paradigms in mammalian mitochondrial biogenesis and function
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Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
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YY1 Is a Structural Regulator of Enhancer-Promoter Loops
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The Polycomb-Group Gene Ezh2 Is Required for Early Mouse Development
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Metadata
- Authors
- Donohoe, M. E., Zhang, X., McGinnis, L., Biggers, J., Li, E., & Shi, Y.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1999-10-01
- Volume
- 19
- Issue
- 10
- Pages
- 7237-7244
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W2104744253
- Cited by
- 375
- References
- 31
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- green
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- Donohoe, M. E., Zhang, X., McGinnis, L., Biggers, J., Li, E., & Shi, Y. (1999). Targeted Disruption of Mouse Yin Yang 1 Transcription Factor Results in Peri-Implantation Lethality. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.19.10.7237
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
