Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Wang, Zhiping; Dillon, Tara J.; Pokala, Viji; Mishra, Snigdha; Labudda, Kirstin; Hunter, Brian; Stork, Philip J. S.

doi:10.1128/mcb.26.6.2130-2145.2006

Cited by 152

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Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Wang, Zhiping, Dillon, Tara J., Pokala, Viji, Mishra, Snigdha, Labudda, Kirstin, Hunter, Brian, Stork, Philip J. S.·2006·Molecular and Cellular Biology

DOI 10.1128/mcb.26.6.2130-2145.2006

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Trk Receptors: Roles in Neuronal Signal Transduction
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“In this manner, the recruitment of C3G/Crk to the PM enables receptor tyrosine kinases to activate Rap1 (29, 32, 66).”
Background
Ras signalling on the endoplasmic reticulum and the Golgi
Chiu, V. K., Bivona, T., Hach, A., Sajous, J. B., Silletti, J., Wiener, H., Johnson, R. L., Cox, A. D., & Philips, M. R. (2002) · Nature Cell Biology · doi:10.1038/ncb783 · Cited by 594 · cited 1×
“Activation of Ras on Golgi membranes can be achieved via the Ras-GEF, RasGRP1, and is distinct from PM-directed Ras activation via Grb2/SOS (7, 16 ).”
Background
Identification and Characterization of RA-GEF-2, a Rap Guanine Nucleotide Exchange Factor That Serves as a Downstream Target of M-Ras
Gao, X., Satoh, T., Liao, Y., Song, C., Hu, C.-D., Kariya, K.-I., & Kataoka, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105760200 · Cited by 106

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Authors: Wang, Z., Dillon, T. J., Pokala, V., Mishra, S., Labudda, K., Hunter, B., & Stork, P. J. S.
Venue: Molecular and Cellular Biology
Publisher: Informa UK Limited
Published: 2006-03-01
Volume: 26
Issue: 6
Pages: 2130-2145
ISSN: 1098-5549
DOI: 10.1128/mcb.26.6.2130-2145.2006
Cited by: 152
References: 3
Language: en
Licence: journals.asm.org/non-commercial-tdm-license (tdm)

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Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

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