The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.
Metabolic Engineering of Saccharomyces cerevisiae
Open accessAbstract
SUMMARY: Comprehensive knowledge regarding Saccharomyces cerevisiae has accumulated over time, and today S. cerevisiae serves as a widley used biotechnological production organism as well as a eukaryotic model system. The high transformation efficiency, in addition to the availability of the complete yeast genome sequence, has facilitated genetic manipulation of this microorganism, and new approaches are constantly being taken to metabolicially engineer this organism in order to suit specific needs. In this paper, strategies and concepts for metabolic engineering are discussed and several examples based upon selected studies involving S. cerevisiae are reviewed. The many different studies of metabolic engineering using this organism illustrate all the categories of this multidisciplinary field: extension of substrate range, improvements of producitivity and yield, elimination of byproduct formation, improvement of process performance, improvements of cellular properties, and extension of product range including heterologous protein production.
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Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network
Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research · doi:10.1101/gr.234503 · Cited by 1,069
Self-citationConstraints to Commercialization of Algal Fuels
Chisti, Y. (2013) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2013.07.020 · Cited by 719
Metabolic engineering for improved fermentation of pentoses by yeasts
Jeffries, T. W., & Jin, Y.-S. (2004) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-003-1450-0 · Cited by 499
Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., Si, T., & Zhao, H. (2015) · ACS Synthetic Biology · doi:10.1021/sb500255k · Cited by 356
Factors affecting ethanol fermentation using Saccharomyces cerevisiae BY4742
Lin, Y., Zhang, W., Li, C., Sakakibara, K., Tanaka, S., & Kong, H. (2012) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2012.09.019 · Cited by 313
Metadata
- Authors
- Ostergaard, S., Olsson, L., & Nielsen, J.
- Venue
- Microbiology and Molecular Biology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2000-03
- Volume
- 64
- Issue
- 1
- Pages
- 34-50
- ISSN
- 1092-2172 (ISSN-L)
- 1098-5557
- OpenAlex
- W2140670503
- Cited by
- 462
- References
- 122
- FWCI
- 0.55
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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