Cited by 80Clinical Nutrition and GastroenterologyGut microbiota and healthGastrointestinal motility and disorders

Dietary management of D-lactic acidosis in short bowel syndrome.

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Mayne, A J, Handy, D J, Preece, M A, George, R H, Booth, I W·1990·Archives of Disease in Childhood

Abstract

Manipulation of carbohydrate intake was used to treat severe, recurrent D-lactic acidosis in a patient with short bowel syndrome. Dietary carbohydrate composition was determined after assessment of D-lactic acid production from various carbohydrate substrates by faecal flora in vitro. This approach may be preferable to repeated courses of antibiotics.

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Registry

Crossref · 10.1136/adc.65.2.229

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  • In a single case report, restriction of monosaccharides and sucrose decreased D-lactate production in a patient with short bowel syndrome, preventing neurotoxicity.

    “In a single case report, restriction of monosaccharides and sucrose was shown to decrease D-lactate production in a patient with short bowel syndrome, preventing neurotoxicity.150”

    From The Gut Microbiome and the Brain (2014) · cites this paper as [150]

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Research works printed but not linked: 1

  1. Carr DB, Shih VE, Richter JM, Martin JB. D-lactic acidosis stimulating a hypothalmic syndrome after bowel by-pass. Ann Neurol 1982;11:195-7.

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Authors
Mayne, A. J., Handy, D. J., Preece, M. A., George, R. H., & Booth, I. W.
Affiliations
University of Birmingham (GB)
Venue
Archives of Disease in Childhood
Publisher
BMJ
Published
1990-02-01
Volume
65
Issue
2
Pages
229-231
ISSN
  • 0003-9888 (ISSN-L)
  • 1468-2044
OpenAlex
W2167200219
Cited by
80
References
6
Citations by year
2025: 1 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 3 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 4 · 2014: 2 · 2013: 4
FWCI
2.42
Type
journal article
Language
en
Open access
Locations
  • Archives of Disease in Childhood (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords
D-lactic acidosis, short bowel syndrome, dietary management, carbohydrate intake, carbohydrate composition, fecal microbiota, D-lactate production, antibiotics
MeSH terms
Acidosis, Lactic, Child, Colon, Dietary Carbohydrates, Female, Humans, Lactates, Lactobacillus, Malabsorption Syndromes, Short Bowel Syndrome, Lactic Acid, Carbohydrate Metabolism

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