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Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
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“A UK database identified an incidence of severe infection of 6.98/100 PYs in patients administered tocilizumab, which is significantly higher than the incidence found with etanercept”
From Targeting Interleukin-6 Signaling in Clinic (2019) · cites this paper as Rutherford et al., 2018
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Research works printed but not linked: 19
- Subesinghe, 2016, A large two-centre study in to rates of influenza and pneumococcal vaccination and infection burden in rheumatoid arthritis in the UK, BMC Musculoskelet Disord, 17, 322, 10.1186/s12891-016-1187-4 · DOI
- Lacaille, 2008, Use of nonbiologic disease-modifying antirheumatic drugs and risk of infection in patients with rheumatoid arthritis, Arthritis Rheum, 59, 1074, 10.1002/art.23913 · DOI
- Dixon, 2011, The association between systemic glucocorticoid therapy and the risk of infection in patients with rheumatoid arthritis: systematic review and meta-analyses, Arthritis Res Ther, 13, R139, 10.1186/ar3453 · DOI
- Curtis, 2007, Risk of serious bacterial infections among rheumatoid arthritis patients exposed to tumor necrosis factor alpha antagonists, Arthritis Rheum, 56, 1125, 10.1002/art.22504 · DOI
- Galloway, 2011, Rheumatology, 50, 124, 10.1093/rheumatology/keq242 · DOI
- Askling, 2007, Time-dependent increase in risk of hospitalisation with infection among Swedish RA patients treated with TNF antagonists, Ann Rheum Dis, 66, 1339, 10.1136/ard.2006.062760 · DOI
- Singh, 2011, Adverse effects of biologics: a network meta-analysis and Cochrane overview, Cochrane Database Syst Rev, 2
- Listing, 2005, Infections in patients with rheumatoid arthritis treated with biologic agents, Arthritis Rheum, 52, 3403, 10.1002/art.21386 · DOI
- Sakai, 2015, Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry, Arthritis Res Ther, 17, 74, 10.1186/s13075-015-0583-8 · DOI
- Watson, 2005, The British Society for rheumatology biologics register, Ann Rheum Dis, 64, iv42, 10.1136/ard.2005.042499 · DOI
- Vallejo, 2017, SAT0099 Polypharmacy is associated with an increased risk of adverse outcomes in patients with rheumatoid arthritis, Annals of the rheumatic diseases, 76, 806, 10.1136/annrheumdis-2017-eular.2262 · DOI
- Curtis, 2014, Risk of hospitalized bacterial infections associated with biologic treatment among US veterans with rheumatoid arthritis, Arthritis Care Res, 66, 990, 10.1002/acr.22281 · DOI
- Zink, 2014, Evaluation of the RABBIT Risk score for serious infections, Ann Rheum Dis, 73, 1673, 10.1136/annrheumdis-2013-203341 · DOI
- Gabay, 2013, Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial, Lancet, 381, 1541, 10.1016/S0140-6736(13)60250-0 · DOI · Paper page
- Smolen, 2016, Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study, Lancet, 388, 2763, 10.1016/S0140-6736(16)31651-8 · DOI
- Richter, 2016, Impact of treatment with biologic DMARDs on the risk of sepsis or mortality after serious infection in patients with rheumatoid arthritis, Ann Rheum Dis, 75, 1667, 10.1136/annrheumdis-2015-207838 · DOI
- Abraham, 1995, Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group, JAMA, 273, 934, 10.1001/jama.1995.03520360048038 · DOI
- Abraham, 1998, Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group, Lancet, 351, 929, 10.1016/S0140-6736(05)60602-2 · DOI
- Qiu, 2013, Antitumor necrosis factor therapy is associated with improved survival in clinical sepsis trials: a meta-analysis, Crit Care Med, 41, 2419, 10.1097/CCM.0b013e3182982add · DOI
Cited by
Sorted by citations
Targeting Interleukin-6 Signaling in Clinic
Kang, S., Tanaka, T., Narazaki, M., & Kishimoto, T. (2019) · Immunity · doi:10.1016/j.immuni.2019.03.026 · Cited by 904
COVID-19 infection and rheumatoid arthritis: Faraway, so close
Favalli, E. G., Ingegnoli, F., De Lucia, O., Cincinelli, G., Cimaz, R., & Caporali, R. (2020) · Autoimmunity Reviews · doi:10.1016/j.autrev.2020.102523 · Cited by 454
Galloway, J. B., Norton, S., Barker, R. D., Brookes, A., Carey, I., Clarke, B. D., Jina, R., Reid, C., Russell, M. D., Sneep, R., et al. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.05.064 · Cited by 206
Self-citation
Metadata
- Authors
- Rutherford, A. I., Subesinghe, S., Hyrich, K. L., & Galloway, J. B.
- Venue
- Annals of the Rheumatic Diseases
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 77
- Issue
- 6
- Pages
- 905-910
- ISSN
- 0003-4967
- Cited by
- 109
- References
- 0
- Language
- en
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- CoChat. (2026). Citation check: Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. https://app.cochat.ai/papers/10.1136/annrheumdis-2017-212825
- The paper
- Rutherford, A. I., Subesinghe, S., Hyrich, K. L., & Galloway, J. B. (2018). Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Annals of the Rheumatic Diseases. https://doi.org/10.1136/annrheumdis-2017-212825