Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density
Open accessAbstract
Objective To examine variables associated with bone mineral density (BMD) in patients with rheumatoid arthritis (RA).Methods We investigated 373 patients with low to moderately active RA. Patients with low disease activity were recruited from a cohort of patients in clinical remission. Patients with moderately active disease were included in a trial comparing the effects of long term high intensity exercise programme and conventional physical therapy. Demographic and clinical data were collected. Bone mineral density (BMD) was measured by means of dual x ray absorptiometry (DXA). Associations between demographic and clinical measurements on the one hand and BMD on the other were investigated in regression analyses.Results The patient group consisted of middle aged, mainly female, patients. The median (interquartile range) disease duration was 7 (4 to 13) years, the mean disease activity score (standard deviation) was 3.2 (1.4). Of the group, 66% was rheumatoid factor positive, and 83% (n = 304) had never used corticosteroids. The median Larsen score of hands and feet was 27 (5 to 61). Greater age and low body mass index were related to low BMD at the hip and spine. High Larsen score for hands and feet was significantly associated with low BMD at the hip. The use of corticosteroids was not independently associated with BMD. The results of the multiple regression analyses also applied to the subgroup of corticosteroid naive patients.Conclusion BMD data of patients with low to moderately active RA demonstrated an association between high radiological RA damage and low BMD at the hip, which suggests an association between the severity of RA and the risk of generalised bone loss, which also occurred in corticosteroid naive patients.
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Systemic bone loss and increased fracture risk are important components of RA.
“In addition to focal bone erosions and periarticular bone loss, systemic bone loss and increased fracture risk are important components of RA (224, 239, 420 -422).”
From Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease (2008) · cites this paper as [421]
Cites
Arnett, F. C., Edworthy, S. M., Bloch, D. A., McShane, D. J., Fries, J. F., Cooper, N. S., Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., et al. (1988) · Arthritis & Rheumatism · doi:10.1002/art.1780310302 · Cited by 19,753 · see citing works
Revised Criteria for the Classification of Rheumatoid Arthritis
Arnett, F. C. (1990) · Orthopaedic Nursing · doi:10.1097/00006416-199003000-00011 · Cited by 7,742 · see citing works
Measurement of patient outcome in arthritis
Fries, J. F., Spitz, P. W., Kraines, R. G., & Holman, H. R. (1980) · Arthritis & Rheumatism · doi:10.1002/art.1780230202 · Cited by 4,373 · see citing works
Professor Kanis, J. A., Melton, L. J., Christiansen, C., Johnston, C. C., & Khaltaev, N. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090802 · Cited by 3,849 · see citing works
Hochberg, M. C., Chang, R. W., Dwosh, I. L., Lindsey, S. M., Pincus, T., & Wolfe, F. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780350502 · Cited by 879 · see citing works
Development of a disease activity score based on judgment in clinical practice by rheumatologists.
van der Heijde, D. M. F. M., Hof, M. V. '., van Riel, P. L., & van de Putte, L. B. (1993) · PubMed · Cited by 787 · see citing works
Interim Report and Recommendations of the World Health Organization Task-Force for Osteoporosis
Genant, H. K., Cooper, C. C., Poór, G., Reid, I. R., Ehrlich, G. E., Kanis, J. A., Nordin, B. E. C., Barrett-Connor, E. L., Black, D. M., Bonjour, J., et al. (1999) · Osteoporosis International · doi:10.1007/s001980050224 · Cited by 785 · see citing works
Generalised bone loss in patients with early rheumatoid arthritis.
GOUGH, A. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91049-9 · Cited by 630 · see citing works
Rheumatoid arthritis, corticosteroid therapy and hip fracture.
Cooper, C. C., Coupland, C. A. C., & Mitchell, M. (1995) · Annals of the Rheumatic Diseases · doi:10.1136/ard.54.1.49 · Cited by 354 · see citing works
Dykman, T. R., Gluck, O. S., Murphy, W. A., Hahn, T. J., & Hahn, B. H. (1985) · Arthritis & Rheumatism · doi:10.1002/art.1780280402 · Cited by 281 · see citing works
BONE MASS MEASUREMENT AND BONE METABOLISM IN RHEUMATOID ARTHRITIS: A REVIEW
Deodhar, A. A., & Woolf, A. D. (1996) · Lara D. Veeken · doi:10.1093/rheumatology/35.4.309 · Cited by 234 · see citing works
Risk of vertebral fracture in women with rheumatoid arthritis.
Spector, T. D., Hall, G. M., McCloskey, E. V., & Kanis, J. (1993) · BMJ · doi:10.1136/bmj.306.6877.558 · Cited by 230 · see citing works
Determinants of axial bone loss in rheumatoid arthritis
Sambrook, P. N., Eisman, J. A., Champion, G. D., Yeates, M. G., POCOCK, N. A., & Eberl, S. (1987) · Arthritis & Rheumatism · doi:10.1002/art.1780300701 · Cited by 200 · see citing works
The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women
Hall, G. M., Spector, T. D., Griffin, A. J., Jawad, A. S. M., Hall, M., & Doyle, D. (1993) · Arthritis & Rheumatism · doi:10.1002/art.1780361105 · Cited by 190 · see citing works
Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis
ten Wolde, S., Breedveld, F. C., Dijkmans, B. A. C., Hermans, J., Vandenbroucke, J. P., van de Laar, M. A. F. J., Markusse, H. M., Janssen, M., & Brink, H. R. V. D. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90535-8 · Cited by 159 · see citing works
Self-citationLaan, R., Buijs, W. C. A. M., Verbeek, A. L. M., Draad, M. P., Corstens, F. H. M., van de Putte, L. B., & van Riel, P. L. (1993) · Annals of the Rheumatic Diseases · doi:10.1136/ard.52.1.21 · Cited by 159 · see citing works
Threefold increased risk of hip fractures with rheumatoid arthritis in Central Finland
Huusko, T., Korpela, M. M., Karppi, P., Avikainen, V., Kautiainen, H., & Sulkava, R. O. (2001) · Annals of the Rheumatic Diseases · doi:10.1136/ard.60.5.521 · Cited by 147 · see citing works
Kröger, H., Honkanen, R., Saarikoski, S., & ALHAVA, E. M. (1994) · Annals of the Rheumatic Diseases · doi:10.1136/ard.53.1.18 · Cited by 130 · see citing works
VERTEBRAL OSTEOPOROSIS IN RHEUMATOID ARTHRITIS PATIENTS: EFFECT OF LOW DOSE PREDNISONE THERAPY
Laan, R., van Riel, P. L. C. M., van Erning, L. J. T. O., Lemmens, J. A. M., Ruijs, S. H. J., & van de Putte, L. B. A. (1992) · Lara D. Veeken · doi:10.1093/rheumatology/31.2.91 · Cited by 118 · see citing works
Henderson, C. J., SPECKER, B. L., Sierra, R. I., Campaigne, B. N., & Lovell, D. J. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200003)43:3 · Cited by 103 · see citing works
Lodder, M. C., Haugeberg, G., Lems, W. F., Uhlig, T., Ørstavik, R., Kostense, P. J., Dijkmans, B. A. C., Kvien, T. K., & Woolf, A. D. (2003) · Arthritis Care & Research · doi:10.1002/art.10996 · Cited by 101 · see citing works
Self-citationOsteoporosis in rheumatoid arthritis
Sambrook, P. N., Spector, T. D., Seeman, E., Bellamy, N., Buchanan, R. R. C., Duffy, D. L., Martin, N. G., Prince, R. L., Owen, E., Silman, A. J., et al. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780380614 · Cited by 92 · see citing works
Martin, J. C., Munro, R., Campbell, M., & Reid, D. M. (1997) · Rheumatology · doi:10.1093/rheumatology/36.1.43 · Cited by 89 · see citing works
PROPOSED MODIFICATION TO LARSEN'S SCORING METHODS FOR HAND AND WRIST RADIOGRAPHS
Scott, D. L., Houssien, D. A., & Laasonen, L. (1995) · Lara D. Veeken · doi:10.1093/rheumatology/34.1.56 · Cited by 82 · see citing works
Molenaar, E. T. H., Voskuyl, A. E., & Dijkmans, B. A. C. (2002) · PubMed · Cited by 76 · see citing works
Self-citationShould we look for osteoporosis in patients with rheumatoid arthritis?
Lems, W. F., & Dijkmans, B. A. C. (1998) · Annals of the Rheumatic Diseases · doi:10.1136/ard.57.6.325 · Cited by 60 · see citing works
Self-citationSambrook, P. N., Raj, A., Hunter, D. J., Naganathan, V., Mason, R. S., & Robinson, B. M. (2001) · PubMed · Cited by 38 · see citing works
Neidhart (2000) · Pure Amsterdam UMC · doi:10.1002/1529-0131(200012)43:12 · Cited by 1 · see citing works
Pope (2001) · doi:10.1002/1529-0131(200106)44:6
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Kearns, A. E., Khosla, S., & Kostenuik, P. J. (2008) · Endocrine Reviews · doi:10.1210/er.2007-0014 · Cited by 824 · see citing works
Regulation of TNF-Induced Osteoclast Differentiation
Yao, Z., Getting, S. J., & Locke, I. C. (2021) · Cells · doi:10.3390/cells11010132 · Cited by 280 · see citing works
Duru, N., van der Goes, M. C., Jacobs, J. W. G., Andrews, T., Boers, M., Buttgereit, F., Caeyers, N., Cutolo, M., Halliday, S., da Silva, J. A. P., et al. (2013) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-203249 · Cited by 275 · see citing works
Osteoporosis in inflammatory joint diseases
Roux, C. (2010) · Osteoporosis International · doi:10.1007/s00198-010-1319-x · Cited by 180 · see citing works
Hauser, B., Riches, P. L., Wilson, J. F., Horne, A. E., & Ralston, S. H. (2014) · Rheumatology · doi:10.1093/rheumatology/keu162 · Cited by 163 · see citing works
Osteoimmunology and osteoporosis
Geusens, P., & Lems, W. F. (2011) · Arthritis Research & Therapy · doi:10.1186/ar3375 · Cited by 148 · see citing works
Self-citationInterleukin-1 is essential for systemic inflammatory bone loss
Polzer, K., Joosten, L. A. B., Gasser, J. A., Distler, J. H. W., Ruiz, G., Baum, W., Redlich, K., Bobacz, K., Smolen, J. S., van den Berg, W., et al. (2009) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2008.104786 · Cited by 143 · see citing works
Coulson, K. A., Reed, G. W., Gilliam, B. E., Kremer, J. M., & Pepmueller, P. H. (2009) · JCR Journal of Clinical Rheumatology · doi:10.1097/rhu.0b013e3181a5679d · Cited by 124 · see citing works
Bréban, S., Briot, K., Kolta, S., Paternotte, S., Ghazi, M., Fechtenbaum, J., & Roux, C. (2012) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2012.01.007 · Cited by 121 · see citing works
Bugatti, S., Bogliolo, L., Vitolo, B., Manzo, A., Montecucco, C., & Caporali, R. F. (2016) · Arthritis Research & Therapy · doi:10.1186/s13075-016-1116-9 · Cited by 113 · see citing works
Osteoprotegerin and RANKL in the pathogenesis of rheumatoid arthritis-induced osteoporosis
Xu, S., Wang, Y., Lu, J., & Xu, J. (2011) · Rheumatology International · doi:10.1007/s00296-011-2175-5 · Cited by 108 · see citing works
Epidemiology of Osteoporosis in Rheumatic Diseases
SINIGAGLIA, L., VARENNA, M., Girasole, G., & Bianchi, G. (2006) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2006.07.002 · Cited by 106 · see citing works
Arthritis Increases the Risk for Fractures — Results from the Women’s Health Initiative
Wright, N. C., Walitt, B. T., Eaton, C. B., CHEN, Z., & the Women’s Health Initiative Investigators (2011) · The Journal of Rheumatology · doi:10.3899/jrheum.101196 · Cited by 98 · see citing works
Ghazi, M., Kolta, S., Briot, K., Fechtenbaum, J., Paternotte, S., & Roux, C. (2011) · Osteoporosis International · doi:10.1007/s00198-011-1584-3 · Cited by 98 · see citing works
Raterman, H. G., & Lems, W. F. (2019) · Drugs & Aging · doi:10.1007/s40266-019-00714-4 · Cited by 93 · see citing works
Self-citationOsteoporosis and rheumatic diseases
Maruotti, N., Corrado, A., & Cantatore, F. P. (2014) · Reumatismo · doi:10.4081/reumatismo.2014.785 · Cited by 92 · see citing works
Raterman, H. G., Bultink, I. E. M., & Lems, W. F. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1787381 · Cited by 82 · see citing works
Self-citationStolina, M., Schett, G. A., Dwyer, D., Vonderfecht, S. L., Middleton, S. C., Duryea, D., Pacheco, E., Van, G. Y., Bolon, B. N., Feige, U., et al. (2009) · Arthritis Research & Therapy · doi:10.1186/ar2879 · Cited by 81 · see citing works
Osteoporosis and fractures in rheumatoid arthritis
Wysham, K. D., Baker, J. F., & Shoback, D. (2021) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000789 · Cited by 80 · see citing works
Osteoporosis in Ankylosing Spondylitis
Magrey, M., & Khan, M. A. (2010) · Current Rheumatology Reports · doi:10.1007/s11926-010-0122-1 · Cited by 73 · see citing works
Bone mineral density in patients with recently diagnosed, active rheumatoid arthritis
Güler-Yüksel, M., Bijsterbosch, J., Goekoop-Ruiterman, Y. P. M., Breedveld, F. C., Allaart, C. F., Vries-Bouwstra, J. K. D., Dijkmans, B. A. C., Lems, W. F., Ronday, H. K., Peeters, A. J., et al. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2007.070839 · Cited by 73 · see citing works
Self-citationCan bone loss in rheumatoid arthritis be prevented?
Vis, M., Güler-Yüksel, M., & Lems, W. F. (2013) · Osteoporosis International · doi:10.1007/s00198-013-2334-5 · Cited by 71 · see citing works
Self-citationSecondary osteoporosis: Pathophysiology & diagnosis
Emkey, G. R., & Epstein, S. (2014) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2014.07.002 · Cited by 68 · see citing works
Recognizing and treating secondary osteoporosis
Walker-Bone, K. E. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.93 · Cited by 68 · see citing works
Ferroptosis as an emerging target in rheumatoid arthritis
Zhao, H., Tang, C. W., Wang, M., Zhao, H., & Zhu, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1260839 · Cited by 64 · see citing works
Lee, S., Park, Y., Park, S., Kim, T., Choi, H., Lee, S., Kim, S., Lee, S., Kim, G., Lee, J., et al. (2012) · International Journal of Rheumatic Diseases · doi:10.1111/j.1756-185x.2012.01729.x · Cited by 60 · see citing works
Oelzner, P., Schwabe, A., Lehmann, G., Eidner, T., Franke, S., Wolf, G., & Hein, G. E. (2008) · Rheumatology International · doi:10.1007/s00296-008-0576-x · Cited by 58 · see citing works
Book, C., Karlsson, M. G., Åkesson, K., & Jacobsson, L. (2008) · Scandinavian Journal of Rheumatology · doi:10.1080/03009740801998747 · Cited by 58 · see citing works
Cardiovascular disease in rheumatoid arthritis: Single-center hospital-based cohort study in France
Assous, N., Touzé, E., Meune, C., Kahan, A., & Allanore, Y. (2006) · Joint Bone Spine · doi:10.1016/j.jbspin.2006.10.001 · Cited by 53 · see citing works
Chen, J., Hsu, C., Yu, S., Ko, C., Chiu, W.-C., Lai, H., Chen, Y., Su, Y., & Cheng, T. (2019) · Rheumatology · doi:10.1093/rheumatology/kez655 · Cited by 50 · see citing works
Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines
Drapkina, O. M., Васильевна, К. А., Калинина, А. М., Avdeev, S. N., Викторович, А. М., Алексеева, Л. И., Almazova, I. I., Andreenko, Е. Y., Antipushina, D. N., Balanova, Y. А., et al. (2024) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2024-3996 · Cited by 49 · see citing works
Eekman, D. A., Vis, M., Bultink, I. E. M., Kuik, D. J., Voskuyl, A. E., Dijkmans, B. A. C., & Lems, W. F. (2010) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2009.127787 · Cited by 49 · see citing works
Self-citationOsteoporosis in adult patients with atopic dermatitis: A nationwide population-based study
Wu, C., Lu, Y., Lu, C., Su, Y., Tsai, T., & Wu, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0171667 · Cited by 49 · see citing works
Risk factors for osteoporosis and fractures in rheumatoid arthritis
Baker, R., Narla, R. R., Baker, J. F., & Wysham, K. D. (2022) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2022.101773 · Cited by 48 · see citing works
Low bone mineral density in adult patients with moderate to severe atopic dermatitis
Haeck, I. M., Hamdy, N. A. T., Mik, L. T.-D., Lentjes, E. G. W. M., Verhaar, H. J. J., Knol, M. J., de Bruin-Weller, M. S., & Bruijnzeel-Koomen, C. A. F. M. (2009) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2009.09327.x · Cited by 47 · see citing works
Jurczak, A., Delay, L., Barbier, J., Simon, N., Krock, E., Sándor, K., Agalave, N. M., Rudjito, R., Wigerblad, G., Rogóż, K., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002543 · Cited by 43 · see citing works
Mao, S. S., Li, D., Luo, Y., Syed, Y. S., & Budoff, M. J. (2015) · Clinical Imaging · doi:10.1016/j.clinimag.2015.09.016 · Cited by 42 · see citing works
Mori, Y., Kuwahara, Y., Chiba, S., Kogre, A., Baba, K., Kamimura, M., & Itoi, E. (2015) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-015-0716-9 · Cited by 41 · see citing works
Male patients with rheumatoid arthritis have an increased risk of osteoporosis
Kweon, S.-M., Sohn, D. H., Park, J.-H., Koh, J. H., Park, E., Lee, H., Keun-young Kim, A., Kim, Y., Kim, G.-T., & Lee, S. (2018) · Medicine · doi:10.1097/md.0000000000011122 · Cited by 41 · see citing works
Management of osteoporosis in a pre-menopausal woman
Bhalla, A. K. (2010) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2010.01.006 · Cited by 39 · see citing works
Bone Mineral Density Changes in Patients with Recent-Onset Rheumatoid Arthritis
Hafez, E. A., Mansour, H. E., Hamza, S. H., Moftah, S. G., Younes, T. B., & Ismail, M. A. (2011) · Clinical Medicine Insights Arthritis and Musculoskeletal Disorders · doi:10.4137/cmamd.s7773 · Cited by 38 · see citing works
Kushnir‐Sukhov, N. M., Brittain, E., Reynolds, J. C., Akin, C., & Metcalfe, D. D. (2006) · International Archives of Allergy and Immunology · doi:10.1159/000091172 · Cited by 38 · see citing works
Aeberli, D., Eser, P., Bonél, H., Widmer, J., Caliezi, G., Varisco, P.-A., Möller, B., & Villiger, P. M. (2010) · Arthritis Research & Therapy · doi:10.1186/ar3056 · Cited by 38 · see citing works
Vitamin D levels and bone mass in rheumatoid arthritis
Brance, M. L., Brun, L. R., Lioi, S., Sánchez, A., Abdala, M., & Oliveri, B. (2014) · Rheumatology International · doi:10.1007/s00296-014-3071-6 · Cited by 37 · see citing works
ZHU, T. Y., Griffith, J. F., Qin, L., Hung, V., Fong, T.-N., Kwok, A. W. L., Leung, P., Li, E. K., & Tam, L. (2012) · Calcified Tissue International · doi:10.1007/s00223-012-9644-z · Cited by 37 · see citing works
Oo, W. M., Naganathan, V., Bo, M. T., & Hunter, D. J. (2018) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims.2018.02.02 · Cited by 37 · see citing works
Prevalence and associated factors for falls in women with established inflammatory polyarthritis.
Oswald, A., Pye, S. R., O’Neill, T. W., Bunn, D. K., Gaffney, K., Marshall, T., Silman, A. J., & Symmons, D. P. M. (2006) · PubMed · Cited by 37 · see citing works
Mazzucchelli, R., Pérez‐Fernández, E., Crespí-Villarías, N., Quirós, J., García-Vadillo, A., Espinosa, M. A., Peña, M., Villa, C. C. M., Hita, J. L. M., Martínez-Prada, C., et al. (2018) · RMD Open · doi:10.1136/rmdopen-2018-000671 · Cited by 36 · see citing works
Rheumatoid arthritis and osteoporosis: a bi-directional Mendelian randomization study
Liu, Y., Liu, Y., Chen, Z., Li, H., & Xiao, T. (2021) · Aging · doi:10.18632/aging.203029 · Cited by 36 · see citing works
Xu, Y., & Wu, Q. F. (2018) · Osteoporosis International · doi:10.1007/s00198-018-4648-9 · Cited by 35 · see citing works
Lai, J. C., Shoback, D., Zipperstein, J., Lizaola‐Mayo, B., Tseng, S., & Terrault, N. A. (2015) · Digestive Diseases and Sciences · doi:10.1007/s10620-014-3507-6 · Cited by 35 · see citing works
Inflammatory signaling induced bone loss
Goldring, S. R. (2015) · Bone · doi:10.1016/j.bone.2015.05.024 · Cited by 34 · see citing works
Alemao, E., Joo, S., Kawabata, H., Al, M., Allison, P. D., Mölken, M. R., Frits, M. L., Iannaccone, C. K., Shadick, N. A., & Weinblatt, M. E. (2015) · Arthritis Care & Research · doi:10.1002/acr.22678 · Cited by 33 · see citing works
Iguratimod inhibits osteoclastogenesis by modulating the RANKL and TNF-α signaling pathways
Li, C., Ma, Z., Jian, L., Wang, X.-Y., Sun, L., Liu, X., Yao, Z., & Zhao, J. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107219 · Cited by 33 · see citing works
Rheumatoid arthritis and bone health
Ashai, S., & Harvey, N. C. (2020) · Clinical Medicine · doi:10.7861/clinmed.20.6.rabh · Cited by 31 · see citing works
Advances in biomonitoring technologies for women’s health
Moghimikandelousi, S., Najm, L., Lee, Y., Bayat, F., Prasad, A., Khan, S. A., Bhavan, A., Gao, W. F., Hosseinidoust, Z., & Didar, T. F. (2025) · Nature Communications · doi:10.1038/s41467-025-63501-3 · Cited by 30 · see citing works
A biomechanical sorting of clinical risk factors affecting osteoporotic hip fracture
Luo, Y. (2015) · Osteoporosis International · doi:10.1007/s00198-015-3316-6 · Cited by 29 · see citing works
Mamoto, K., Inui, K., Okano, T., Sugioka, Y., Tada, M., Koike, T., & Nakamura, H. (2016) · Modern Rheumatology · doi:10.1080/14397595.2016.1176625 · Cited by 29 · see citing works
Desai, S. P., Gravallese, E. M., Shadick, N. A., Glass, R. J., Cui, J., Frits, M. L., Chibnik, L. B., Maher, N., Weinblatt, M. E., & Solomon, D. H. (2009) · Rheumatology · doi:10.1093/rheumatology/kep385 · Cited by 27 · see citing works
Dirven, L., Güler-Yüksel, M., de Beus, W. M., Ronday, H. K., Speyer, I., Huizinga, T. W. J., Dijkmans, B. A. C., Allaart, C. F., & Lems, W. F. (2011) · Arthritis Care & Research · doi:10.1002/acr.20612 · Cited by 27 · see citing works
Self-citationUrano, W., Furuya, T., Inoue, E., Taniguchi, A., Urano, T., Kotake, S., Sekita, C., Inoue, S., Hara, M., Momohara, S., et al. (2009) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-009-0073-7 · Cited by 27 · see citing works
Furuya, T., Kotake, S., Inoue, E., Nanke, Y., Yago, T., Hara, M., Tomatsu, T., Kamatani, N., & Yamanaka, H. (2008) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-007-0836-y · Cited by 27 · see citing works
Rajendran, K., Pahal, S., Badnikar, K., Nayak, M. M., Subramanyam, D. N., Vemula, P. K., & Krishnan, U. M. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123184 · Cited by 26 · see citing works
Osteoporosis premenopáusica: ¿cómo tratarla?
Martínez‐Morillo, M., Grados, D., & Holgado, S. (2011) · Reumatología Clínica · doi:10.1016/j.reuma.2011.05.011 · Cited by 25 · see citing works
Sevilla, R. S., Cruz, F., Chiu, C., Xue, D., Bettano, K. A., Zhu, J. J., Chakravarthy, K., Faltus, R., Wang, S., Vanko, A., et al. (2014) · Bone · doi:10.1016/j.bone.2014.11.014 · Cited by 25 · see citing works
Prevalence and associated factors of osteoporosis in female patients with rheumatoid arthritis.
Mobini, M., Kashi, Z., & Ghobadifar, A. (2012) · Europe PMC (PubMed Central) · Cited by 24 · see citing works
Diagnosis, Differential Diagnosis and Treatment of Polymyalgia Rheumatica
Nothnagl, T., & Leeb, B. F. (2006) · Drugs & Aging · doi:10.2165/00002512-200623050-00003 · Cited by 24 · see citing works
Yi, X., Liu, X., Kenney, H. M., Duan, R., Lin, X., Schwarz, E. M., & Yao, Z. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4447 · Cited by 23 · see citing works
Flegar, D., Filipović, M., Šućur, A., Markotić, A., Lukač, N., Šisl, D., Matijašević, M. I., Jajić, Z., Kelava, T., Katavić, V., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.767231 · Cited by 23 · see citing works
Sun, J., Zhang, H., Zhang, Y., Wang, L., Sun, B., Gao, F., & Liu, G. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.03.012 · Cited by 23 · see citing works
Bone mineral density in Indian women with rheumatoid arthritis
Shankar, S., Handa, R., Aneja, R., Marwaha, V., Ammini, A. C., & Aprajita, V. (2008) · Rheumatology International · doi:10.1007/s00296-008-0706-5 · Cited by 23 · see citing works
Strategies for the Prevention and Treatment of Osteoporosis in Patients with Rheumatoid Arthritis
Phillips, K., Aliprantis, A. O., & Coblyn, J. S. (2006) · Drugs & Aging · doi:10.2165/00002512-200623100-00001 · Cited by 23 · see citing works
Rheumatoid arthritis and osteoporosis.
Heidari, B., & Roushan, M. R. H. (2012) · Europe PMC (PubMed Central) · Cited by 22 · see citing works
Rheumatoid arthritis in tight disease control is no longer risk of bone mineral density loss
Yoshii, I., Chijiwa, T., & Sawada, N. (2020) · Osteoporosis and Sarcopenia · doi:10.1016/j.afos.2020.04.002 · Cited by 22 · see citing works
Locking compression plating: a new solution for fractures in rheumatoid patients
Luo, C. (2005) · Modern Rheumatology · doi:10.1007/s10165-005-0392-z · Cited by 22 · see citing works
Changes in bone mineral density over 10 years in patients with early rheumatoid arthritis
Theander, L., Willim, M., Nilsson, J. Å., Karlsson, M. K., Åkesson, K., Jacobsson, L., & Turesson, C. (2020) · RMD Open · doi:10.1136/rmdopen-2019-001142 · Cited by 20 · see citing works
Evaluation of Risk Factors for Falls in Patients with Rheumatoid Arthritis
Mikos, M., Kucharska, E., Lulek, A. M., Kłosiński, M., & Batko, B. P. (2020) · Medical Science Monitor · doi:10.12659/msm.921862 · Cited by 20 · see citing works
Poutoglidou, F., Pourzitaki, C., Μanthou, M. E., Samoladas, E., Saitis, A., Malliou, F., & Kouvelas, D. (2021) · Inflammopharmacology · doi:10.1007/s10787-021-00815-w · Cited by 18 · see citing works
Ewendt, F., Feger, M., & Föller, M. (2021) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02561-y · Cited by 18 · see citing works
Xia, J., Zhang, L., Li, J., Yuan, C., Zhu, X.-W., Qian, Y., Khederzadeh, S., Gu, J.-X., Xu, L., Gao, J.-H., et al. (2022) · BMC Medicine · doi:10.1186/s12916-022-02531-w · Cited by 17 · see citing works
Morimoto, D., Kuroda, S., Kizawa, T., Nomura, K., Higuchi, C., Yoshikawa, H., & Tomita, T. (2009) · Rheumatology · doi:10.1093/rheumatology/kep044 · Cited by 16 · see citing works
Naser, A. N., Odeh, A. K., Sharp, R. C., Qasem, A., Bég, S., & Naser, S. A. (2019) · Microorganisms · doi:10.3390/microorganisms7120646 · Cited by 16 · see citing works
Haugeberg, G., & Emery, P. (2005) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2005.07.013 · Cited by 16 · see citing works
Rogier, R., Ederveen, T. H. A., Wopereis, H., Hartog, A., Boekhorst, J., van Hijum, S. A. F. T., Knol, J., Garssen, J., Walgreen, B., Helsen, M. M. A., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219366 · Cited by 15 · see citing works
Wysham, K. D., Shofer, J. B., Lui, G., Trupin, L. S., Andrews, J. S., Black, D. M., Graf, J. D., Shoback, D., & Katz, P. (2022) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2022.151972 · Cited by 15 · see citing works
Kasher, M., Williams, F. M. K., Freidin, M. B., Cherny, S. S., Malkin, I., CHARGE Inflammation Working Group, & Livshits, G. (2022) · Pain · doi:10.1097/j.pain.0000000000002728 · Cited by 15 · see citing works
Premenopausal Osteoporosis: How to Treat?
Martínez‐Morillo, M., Grados, D., & Holgado, S. (2011) · Reumatología Clínica (English Edition) · doi:10.1016/j.reumae.2011.05.005 · Cited by 15 · see citing works
Kasher, M., Williams, F. M. K., Freidin, M. B., Malkin, I., Cherny, S. S., CHARGE Inflammation Working Group, Benjamin, E. J., Chasman, D. I., Dehghan, A., Ahluwalia, T. S., et al. (2022) · Human Molecular Genetics · doi:10.1093/hmg/ddac061 · Cited by 14 · see citing works
Liu, C., Yang, Y., Sun, D., Wang, C., Wang, H., Jia, S., Liu, L., & Lin, N. (2015) · Rejuvenation Research · doi:10.1089/rej.2015.1688 · Cited by 14 · see citing works
Glucocorticoid-induced Osteoporosis
Jung, J., & Suh, C. (2017) · Korean Journal of Medicine · doi:10.3904/kjm.2017.92.2.142 · Cited by 14 · see citing works
Wafa, H., Alaya, R., Dhia, K., Boughanmi, N., Imene, Z., & Montacer, K. M. (2018) · The Egyptian Rheumatologist · doi:10.1016/j.ejr.2018.01.004 · Cited by 13 · see citing works
Shared Genetic Architecture Between Rheumatoid Arthritis and Varying Osteoporotic Phenotypes
Kasher, M., Freidin, M. B., Williams, F. M. K., Cherny, S. S., Malkin, I., & Livshits, G. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4491 · Cited by 13 · see citing works
Huang, H., Wang, Y., Xie, W., Geng, Y., Gao, D., & Zhang, Z. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.867610 · Cited by 12 · see citing works
The Use of Collagen-Induced Arthritis Animal Model on Studying Bone Metabolism
Poutoglidou, F., Pourzitaki, C., Dardalas, I., Μanthou, M. E., Samoladas, E., & Kouvelas, D. (2020) · Calcified Tissue International · doi:10.1007/s00223-020-00697-0 · Cited by 12 · see citing works
Baldini, C., Sedie, A. D., & Bombardieri, S. (2005) · PubMed · Cited by 12 · see citing works
Suh, S.-P., Kim, C.-W., Jo, Y.-H., & Kang, C.-N. (2015) · Asian Spine Journal · doi:10.4184/asj.2015.9.4.581 · Cited by 11 · see citing works
Inflammation‐Induced Bone Loss in the Rheumatic Diseases
Gravallese, E. M., & Goldring, S. R. (2018) · Wiley eBooks · doi:10.1002/9781119266594.ch58 · Cited by 11 · see citing works
Obstacle avoidance in persons with rheumatoid arthritis walking on a treadmill.
Smulders, E., Schreven, C., van Lankveld, W., Duysens, J., & Weerdesteyn, V. (2009) · PubMed · Cited by 10 · see citing works
Hsu, C., Chen, J., Su, Y., Chen, Y., Lai, H., Yu, S., He, H.-R., & Cheng, T. (2020) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622320981517 · Cited by 10 · see citing works
Tong, J., Xu, S., Wang, J., Zong, H.-X., Chu, Y.-R., Chen, K., & Teng, Y. (2021) · Archives of Osteoporosis · doi:10.1007/s11657-021-01017-1 · Cited by 10 · see citing works
- Authors
- Lodder, M. C., de Jong, Z., Kostense, P. J., Molenaar, E. T. H., Staal, K., Voskuyl, A. E., Hazes, J. M. W., Dijkmans, B. A. C., & Lems, W. F.
- Affiliations
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Erasmus MC (NL)
- Corresponding author
- Lodder, M C
- Venue
- Annals of the Rheumatic Diseases
- Publisher
- Elsevier BV
- Published
- 2004-12
- Volume
- 63
- Issue
- 12
- Pages
- 1576-1580
- ISSN
- 0003-4967 (ISSN-L)
- PMC
- PMC1754831
- OpenAlex
- W2101980834
- Cited by
- 202
- References
- 29
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 5 · 2023: 11 · 2022: 15 · 2021: 19 · 2020: 13 · 2019: 8 · 2018: 9 · 2017: 5 · 2016: 8 · 2015: 14 · 2014: 8 · 2013: 6 · 2012: 12
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of the Rheumatic Diseases (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, other-oa)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Keywords
- rheumatoid arthritis, bone mineral density, osteopenia, disease severity, Larsen score, radiographic damage, corticosteroid use, bone loss, hip bone density, body mass index, age
- MeSH terms
- Adrenal Cortex Hormones, Adult, Aged, Arthritis, Rheumatoid, Female, Femur Neck, Humans, Lumbar Vertebrae, Male, Middle Aged, Osteoporosis, Severity of Illness Index, Bone Density, Body Mass Index, Linear Models, Antirheumatic Agents
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