The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Predicted biological activity of intravitreal VEGF Trap
Abstract
AIM: To compare the intravitreal binding activity of VEGF Trap with that of ranibizumab against vascular endothelial growth factor (VEGF) using a time-dependent and dose-dependent mathematical model. METHODS: Intravitreal half-lives and relative equimolar VEGF-binding activities of VEGF Trap and ranibizumab were incorporated into a first-order decay model. Time-dependent VEGF Trap activities (relative to ranibizumab) for different initial doses (0.5, 1.15, 2 and 4 mg) were calculated and plotted. RESULTS: Seventy-nine days after a single VEGF Trap (1.15 mg) injection, the intravitreal VEGF-binding activity would be comparable to ranibizumab at 30 days. After injection of 0.5, 2 and 4 mg VEGF Trap, the intravitreal VEGF-binding activities (comparable to ranibizumab at 30 days) would occur at 73, 83 and 87 days, respectively CONCLUSION: On the basis of this mathematical model, VEGF Trap maintains significant intravitreal VEGF-binding activity for 10-12 weeks after a single injection.
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Ranibizumab for Neovascular Age-Related Macular Degeneration
Rosenfeld, P. J., Brown, D. M., Heier, J. S., Boyer, D. S., Kaiser, P. K., Chung, C. Y., & Kim, R. Y. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054481 · Cited by 5,886
Self-citationPegaptanib for neovascular age-related macular degeneration
Gragoudas, E. S., Adamis, A. P., Cunningham, E. T., Feinsod, M., & Guyer, D. R. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa042760 · Cited by 2,337
Rosenfeld, P. J., Moshfeghi, A. A., & Puliafito, C. A. (2005) · Ophthalmic Surgery, Lasers and Imaging Retina · doi:10.3928/1542-8877-20050701-14 · Cited by 904
Self-citationPharmacokinetics of Intravitreal Bevacizumab (Avastin)
Bakri, S. J., Snyder, M. R., Reid, J. M., Pulido, J. S., & Singh, R. J. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2007.01.017 · Cited by 683
Preclinical Pharmacokinetics of Ranibizumab (rhuFabV2) after a Single Intravitreal Administration
Gaudreault, J., Fei, D., Rusit, J., Suboc, P., & Shiu, V. (2005) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.04-0601 · Cited by 501
Mordenti, J., Cuthbertson, R. A., Ferrara, N., Thomsen, K., Berleau, L., Licko, V., Allen, P. C., Valverde, C. R., Meng, Y. G., Fei, D. T. W., et al. (1999) · Toxicologic Pathology · doi:10.1177/019262339902700507 · Cited by 350
Saishin, Y., Saishin, Y., Takahashi, K., Silva, R. L. E., Hylton, D., Rudge, J. S., Wiegand, S. J., & Campochiaro, P. A. (2003) · Journal of Cellular Physiology · doi:10.1002/jcp.10246 · Cited by 239
NGUYEN, Q., SHAH, S., Hafiz, G., Quinlan, E., SUNG, J., CHU, K., Cedarbaum, J. M., & Campochiaro, P. A. (2006) · Ophthalmology · doi:10.1016/j.ophtha.2006.05.055 · Cited by 157
PREDICTED BIOLOGIC ACTIVITY OF INTRAVITREAL BEVACIZUMAB
Stewart, M. W. (2007) · Retina · doi:10.1097/iae.0b013e318158ea28 · Cited by 66
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Cited by
Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration
Heier, J. S., Brown, D. M., Chong, V., Korobelnik, J.-F., Kaiser, P. K., Nguyen, Q. D., Kirchhof, B., Ho, A., Ogura, Y., Yancopoulos, G. D., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2012.09.006 · Cited by 2,485
Brown, D. M., Heier, J. S., Clark, W. L., Boyer, D. S., Vitti, R., Berliner, A. J., Zeitz, O., Sandbrink, R., Zhu, X., & Haller, J. A. (2013) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2012.09.026 · Cited by 365
INTRAVITREAL INJECTION OF THERAPEUTIC AGENTS
PEYMAN, G. A., LAD, E. M., & MOSHFEGHI, D. M. (2009) · Retina · doi:10.1097/iae.0b013e3181a94f01 · Cited by 255
Bakall, B., Folk, J. C., Boldt, H. C., Sohn, E. H., Stone, E. M., Russell, S. R., & Mahajan, V. B. (2013) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2013.02.017 · Cited by 229
Stewart, M. W., Rosenfeld, P. J., Penha, F. M., Wang, F., Yehoshua, Z., Bueno-Lopez, E., & Lopez, P. F. (2011) · Retina · doi:10.1097/iae.0b013e31822c290f · Cited by 225
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Metadata
- Authors
- Stewart, M. W., & Rosenfeld, P. J.
- Venue
- British Journal of Ophthalmology
- Publisher
- BMJ
- Published
- 2008-03-20
- Volume
- 92
- Issue
- 5
- Pages
- 667-668
- ISSN
- 0007-1161 (ISSN-L)
- OpenAlex
- W2143874967
- Cited by
- 375
- References
- 9
- FWCI
- 9.11
- Type
- journal article
- Language
- en
- Open access
- closed
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