Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
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Withdrawal syndromes after decrease or discontinuation of antidepressants may be associated with additional clinical manifestations, including modifications of the illness course such as switching to mania or other forms of excessive behavioral activations, loss of clinical effects, and refractoriness to treatment.
“Withdrawal syndromes after decrease or discontinuation of antidepressants may be associated with additional clinical manifestations. They include modifications of the illness course, such as switching to mania or other forms of excessive behavioral activations [24], but also loss of clinical effects and refractoriness to treatment; they have been reported with SSRI and SNRI [5, 6, 27].”
From Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications (2020) · cites this paper as [24]
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- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1980-03-29
- Volume
- 280
- Issue
- 6218
- Pages
- 910-912
- ISSN
- 0007-1447 (ISSN-L)
- 1468-5833
- OpenAlex
- W4214835118
- Cited by
- 86
- References
- 3
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 1 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 3 · 2015: 2 · 2014: 2 · 2012: 2
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.bmj.com/company/legal-information/terms-conditions/legal-information/tdm-licencepolicy (tdm)
- Locations
- BMJ (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Synthesis and pharmacology of benzodiazepine derivatives
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Keywords
- benzodiazepines, diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, flurazepam
- MeSH terms
- Benzodiazepines, Chlordiazepoxide, Clorazepate Dipotassium, Diazepam, Flurazepam, Humans, Lorazepam, Medazepam, Nitrazepam, Oxazepam, Safety, Substance Withdrawal Syndrome, Temazepam, Triazolam, Substance-Related Disorders
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