Acceleration of ventricular rate by amiodarone in atrial fibrillation associated with the Wolff-Parkinson-White syndrome
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Amiodarone has proved to be a valuable drug in atrial fibrillation associated with the Wolff-Parkinson-White syndrome. When it was administered to a patient with this syndrome in atrial fibrillation, who had previously suffered an inferior myocardial infarction, the ventricular rate accelerated from 170 to 230 beats/minute.This unusual case emphasises the need for full electrophysiological assessment of patients with the Wolff-Parkinson-White syndrome for whom amiodarone treatment is being considered.
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In pre-excited atrial fibrillation, amiodarone may not be as safe as previously thought.
“In case of pre-excited AF, amiodarone may not be as a safe as previously thought.316 -319”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [318]
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Effect of amiodarone in the Wolff-Parkinson-White syndrome
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Effect of drugs in the wolff-parkinson-white syndrome
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2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia
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- Authors
- Sheinman, B. D., & Evans, T.
- ORCID
- Sheinman, Bryan D
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1982-10-09
- Volume
- 285
- Issue
- 6347
- Pages
- 999-1000
- ISSN
- 0007-1447 (ISSN-L)
- 1468-5833
- OpenAlex
- W2084821088
- Cited by
- 39
- References
- 5
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2016: 2 · 2015: 6
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.bmj.com/company/legal-information/terms-conditions/legal-information/tdm-licencepolicy (tdm)
- Locations
- BMJ (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medical Research Council
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- amiodarone, atrial fibrillation, Wolff-Parkinson-White syndrome, inferior myocardial infarction, electrophysiological assessment, antiarrhythmic drugs
- MeSH terms
- Aged, Amiodarone, Atrial Fibrillation, Benzofurans, Electrocardiography, Humans, Male, Tachycardia, Wolff-Parkinson-White Syndrome
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