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Cited by 285Virology and Viral DiseasesChild Nutrition and Water AccessVitamin D Research Studies

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Vitamin A supplements and mortality related to measles: A randomised clinical trial

Open access
Barclay, A J, Foster, A, Sommer, A·1987·BMJ
DOI 10.1136/bmj.294.6567.294
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Abstract

One hundred and eighty children admitted with measles were randomly allocated to receive routine treatment alone or with additional large doses of vitamin A (200,000 IU orally immediately and again the next day). Baseline characteristics of the two groups were virtually identical for age, severity of measles, and vitamin A and general nutritional states. In 91% of the children serum vitamin A concentrations were less than 0.56 mumol/l. Of the 88 subjects given vitamin A supplements, six (7%) died; of the 92 controls, 12 (13%) died (p = 0.13). This difference in mortality was most obvious for children aged under 2 years (one death out of 46 children receiving supplements versus seven deaths out of 42 controls; p less than 0.05) and for cases complicated by croup or laryngotracheobronchitis. Mortality was several times higher in marasmic than in better nourished children, regardless of study allocation (p less than 0.01).

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Citations

Cites

Research works printed but not linked: 3

  1. SommerA, KatzJ, Tarwotio I. Increased risk ofrespiratory diseaseand diarrhoea in children with pre-existing mild vitamin A deficiency. AmJ Clin Nuir 1984;40:1090-5.
  2. Kochanowski BA, Ross AC. Stimulation of humoral immunity by vitamin A during suckling and postweaning in the rat. J Nutr (in press).
  3. De Vroey C. Epidemiology of ringworm (Dermatophytosis). Seminars in Dermatology 1985;4:185200.

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Metadata

Authors
Barclay, A. J., Foster, A., & Sommer, A.
Affiliations
Johns Hopkins University (US)
ORCID
Venue
BMJ
Publisher
BMJ
Published
1987-01-31
Volume
294
Issue
6567
Pages
294-296
ISSN
  • 0007-1447 (ISSN-L)
  • 0959-8138
  • 1468-5833
DOI
10.1136/bmj.294.6567.294
OpenAlex
W2002591611
Cited by
285
References
34
Citations by year
2026: 1 · 2025: 1 · 2023: 3 · 2022: 7 · 2021: 3 · 2020: 10 · 2019: 5 · 2018: 1 · 2017: 4 · 2015: 7 · 2014: 3 · 2013: 6 · 2012: 4
FWCI
10.08
Type
journal article
Language
en
Open access
Locations
  • BMJ (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
  • Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Vitamin D Research Studies
Keywords
vitamin A supplementation, measles, measles mortality, children, vitamin A deficiency, marasmus, croup, nutritional status
MeSH terms
Child, Child, Preschool, Clinical Trials as Topic, Humans, Infant, Measles, Random Allocation, Tanzania, Vitamin A, Vitamin A Deficiency

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Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.