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IMPACT OF VITAMIN A SUPPLEMENTATION ON CHILDHOOD MORTALITY
Open accessAbstract
450 villages in northern Sumatra were randomly assigned to either participate in a vitamin A supplementation scheme (n = 229) or serve for 1 year as a control (n = 221). 25 939 preschool children were examined at baseline and again 11 to 13 months later. Capsules containing 200 000 IU vitamin A were distributed to preschool children aged over 1 year by local volunteers 1 to 3 months after baseline enumeration and again 6 months later. Among children aged 12-71 months at baseline, mortality in control villages (75/10 231, 7.3 per 1000) was 49% greater than in those where supplements were given (53/10 919, 4.9 per 1000) (p less than 0.05). The impact of vitamin A supplementation seemed to be greater in boys than in girls. These results support earlier observations linking mild vitamin A deficiency to increased mortality and suggest that supplements given to vitamin A deficient populations may decrease mortality by as much as 34%.
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Cited by
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Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C., & Song, S.-Y. (2004) · Immunity · doi:10.1016/j.immuni.2004.08.011 · Cited by 1,541
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Greenland, S. (2000) · International Journal of Epidemiology · doi:10.1093/ije/29.4.722 · Cited by 1,156
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Victora, C. G., Habicht, J.-P., & Bryce, J. (2004) · American Journal of Public Health · doi:10.2105/ajph.94.3.400 · Cited by 1,056
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Metadata
- Authors
- Sommer, A., Djunaedi, E., Loeden, A. A., Tarwotjo, I., West, K., Tilden, R., Mele, L., & The Aceh Study Group
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1986-05
- Volume
- 327
- Issue
- 8491
- Pages
- 1169-1173
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2140409429
- Cited by
- 680
- References
- 0
- FWCI
- 23.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Sommer, A., Djunaedi, E., Loeden, A. A., Tarwotjo, I., West, K., Tilden, R., Mele, L., & The Aceh Study Group. (1986). IMPACT OF VITAMIN A SUPPLEMENTATION ON CHILDHOOD MORTALITY. The Lancet. https://doi.org/10.1016/s0140-6736(86)91157-8
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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