The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports.
Open accessAbstract
OBJECTIVE--To examine the possible contribution of sedation with propofol in the deaths of children who were intubated and required intensive care. DESIGN--Case note review. SETTING--Three intensive care units. SUBJECTS--Five children with upper respiratory tract infections aged between 4 weeks and 6 years. RESULTS--Four patients had laryngotracheo-bronchitis and one had bronchiolitis. All were sedated with propofol. The clinical course in all five cases was remarkably similar: an increasing metabolic acidosis was associated with brady-arrhythmia and progressive myocardial failure, which did not respond to resuscitative measures. All children developed lipaemic serum after starting propofol. These features are not usually associated with respiratory tract infections. No evidence was found of viral myocarditis, which was considered as a possible cause of death. CONCLUSION--Although the exact cause of death in these children could not be defined, propofol may have been a contributing factor.
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Cites
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-499_7 · Cited by 1,564
PHARMACOKINETIC MODEL DRIVEN INFUSION OF PROPOFOL IN CHILDREN
MARSH, B., WHITE, M., MORTON, N., & KENNY, G. N. C. (1991) · British Journal of Anaesthesia · doi:10.1093/bja/67.1.41 · Cited by 1,168
HAEMODYNAMIC CHANGES DURING ANAESTHESIA INDUCED AND MAINTAINED WITH PROPOFOL
Claeys, M., Gepts, E., & Camu, F. (1988) · British Journal of Anaesthesia · doi:10.1093/bja/60.1.3 · Cited by 499
COMPARISON OF PROPOFOL AND MIDAZOLAM FOR SEDATION IN CRITICALLY ILL PATIENTS
Aitkenhead, A., Willatts, S., Park, G., Collins, C., Ledingham, I., Pepperman, M., David Coates, P., Bodenham, A., Smith, M., & Wallace, P. M. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90770-8 · Cited by 213
Beller, J. P., Pottecher, T., Lugnier, A. A. J., Mangin, P. J., & Otteni, J. C. (1988) · British Journal of Anaesthesia · doi:10.1093/bja/61.5.583 · Cited by 116
Harris, C. E., Grounds, R. M., MURRAY, A. M., Lumley, J., Royston, D., & Morgan, M. K. (1990) · Anaesthesia · doi:10.1111/j.1365-2044.1990.tb14777.x · Cited by 85
Fentanyl, fads, and folly: Who will adopt the therapeutic orphans?
Kauffman, R. E. (1991) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)82409-6 · Cited by 31
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Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827e83af · Cited by 9,694
Propofol infusion syndrome in children
Bray (1998) · Pediatric Anesthesia · doi:10.1046/j.1460-9592.1998.00282.x · Cited by 533
Kam, P. C. A., & Cardone, D. (2007) · Anaesthesia · doi:10.1111/j.1365-2044.2007.05055.x · Cited by 498
Propofol infusion syndrome: a structured literature review and analysis of published case reports
Hemphill, S., McMenamin, L., Bellamy, M. C., & Hopkins, P. M. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.12.025 · Cited by 331
Propofol: The Challenges of Formulation
Baker, M. T., Naguib, M., & Warltier, D. C. (2005) · Anesthesiology · doi:10.1097/00000542-200510000-00026 · Cited by 305
Metadata
- Authors
- Parke, T. J., Stevens, J. E., Rice, A. S., Greenaway, C. L., Bray, R. J., Smith, P. J., Waldmann, C. S., & Verghese, C.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1992-09-12
- Volume
- 305
- Issue
- 6854
- Pages
- 613-616
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2076829739
- Cited by
- 579
- References
- 7
- FWCI
- 21.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Parke, T. J., Stevens, J. E., Rice, A. S., Greenaway, C. L., Bray, R. J., Smith, P. J., Waldmann, C. S., & Verghese, C. (1992). Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. BMJ. https://doi.org/10.1136/bmj.305.6854.613
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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