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Cited by 533

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Propofol infusion syndrome in children

Bray·1998·Pediatric Anesthesia

Abstract

Department of Anaesthesia, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UKThe use of propofol infusions to sedate children in intensive care units has decreased after reports of deaths from myocardial failure. More recently it has been suggested that propofol might have been prematurely condemned. Information about 18 children who had received propofol infusions and suffered serious unwanted effects was used to define their common features. Three of the deaths occurred in one intensive care unit where propofol infusions had been used between 1987 and 1993. During this period 44 children with respiratory tract infections had been admitted to this unit and sedated for at least 48 h. Nine had received long‐term (>48 h), high‐dose (>4 mg·kg·1·h‐1) propofol infusions and three had developed progressive myocardial failure and died. There was a significant association between receiving a long‐term, high‐dose propofol infusion and developing progressive myocardial failure (Fisher's Exact Test, two‐tailed hypothesis, P=0.0128) although a causative relationship could not be proved.

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Crossref · 10.1046/j.1460-9592.1998.00282.x

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Metadata

Authors
Bray
Venue
Pediatric Anesthesia
Publisher
Wiley
Published
1998-11
Volume
8
Issue
6
Pages
491-499
ISSN
  • 1155-5645 (ISSN-L)
  • 1460-9592
OpenAlex
W2154727969
Cited by
533
References
6
FWCI
8.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Propofol infusion syndrome in children. https://app.cochat.ai/papers/10.1046/j.1460-9592.1998.00282.x
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Bray. (1998). Propofol infusion syndrome in children. Pediatric Anesthesia. https://doi.org/10.1046/j.1460-9592.1998.00282.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.